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Developmental changes in GABAA tonic inhibition are compromised by multiple mechanisms in preadolescent dentate gyrus granule cells
SudipPit, GyuSeungLee, JinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 15 695-702 (8 pages)
in the presence of exogenous GABA. Itonic sensitivity to L-655,708, a GABAAR α5 subunit inverse agonist, gradually decreased during the preadolescent period in the presence of NPA or exogenous GABA. Finally, Western blot analysis showed that the expression of the GABAAR α5 subunit in the dentate gyrus gradually decreased with age. Collectively, our results suggested that the Itonic regulation of altered GATs is under the final tune of GABAAR α5 subunit activation in DGGCs at different ages. -
Ahcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association
PilWhanPark, JeongYealAhn, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.4 13 433-440 (8 pages)
Inositol-1,4,5-triphosphate [IP3] receptors binding protein released with IP3 (IRBIT) was previously reported as an activator of NBCe1-B. Recent studies have characterized IRBIT homologue S-Adenosylhomocysteine hydrolase-like 2 (AHCYL2). AHCYL2 is highly homologous to IRBIT (88%) and heteromerizes with IRBIT. The two important domains in the N-terminus of AHCYL2 are a PEST domain and a coiled-coil domain which are highly comparable to those in IRBIT. Therefore, in this study, we tried to... -
Mathematics using multiple senses: Developing finger gnosis with three- and four-year-olds in an era of multi-touch technologies
Nathalie Sinclair, David Pimm 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 11 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2015, Vol.9 No.3 7 99-110 (11 pages)
In this paper, we explore a richer sense of finger gnosis (finger knowledge) with respect to three- and four-year-olds’ interactions with a novel iPad application (TouchCounts), focusing on their responses to an “inverse subitising” task. The direct and tactile nature of their engagement with TouchCounts leads to a striking shift from incrementing using the index finger to deployment of several fingers all-at-once (in a cardinal touch gesture) to achieve a given target number that is then... -
A Comparison of Three Bayesian Point Estimates for Cross-Classified Multiple Membership Growth Curve Modeling
Chung Hyewon, Jeon Hyeonjeong, Park Soyoung 한국교육학회 교육학연구 26 Pages
한국교육학회 교육학연구 2021, 59권 7호 7 167-192 (26 pages)
mode estimates of the between-school variances in the intercept and slope were substantially overestimated. In general, with the inverse Wishart prior, the Markov chain Monte Carlo (MCMC) posterior median is recommended for cross-classified multiple membership growth curve modeling, except under certain conditions. With the uniform prior, the MCMC mode is recommended for estimating cross-classified multiple membership growth curve modeling rather than the MCMC posterior mean or posterior median. -
An Analysis of Unit Assessments in Elementary-School Mathematics Textbooks
Nam Jinyoung 경인교육대학교 교육연구원 교육논총 21 Pages
경인교육대학교 교육연구원 교육논총 제 41권 특별호 8 133-153 (21 pages)
The 2015 revised elementary-school curriculum reduced the number of standardized tests in favor of course-centered assessments. As a consequence, textbook unit assessments have become more central and important. The present study analyzes unit assessments in elementary-school mathematics textbooks, developed in accordance with the 2015 revised curriculum, to determine whether they provide even coverage of mathematical content and competencies. The findings show that main lesson content is... -
뇌기반 기독교교육의 새로운 모형 연구
한국종교교육학회 종교교육학연구 2016, 제 51권 6 129-151 (23 pages)
신경과학의 급격한 발전으로 기독교교육은 물론 인접 학문까지 과거에 예상하지 못한 변화를겪고 있다. 특히 최근 학습자의 전인적 측면에 관심을 갖고 있는 기독교교육은 신경과학과의 학제적 대화를 통해서 뇌의 특성과 기능에 주목하게 되었다. 신경과학적 논의가 기독교교육에 함의하는 연구결과들을 중심으로 뇌기반 기독교교육의 모형을 구성하는 것을 목적으로 삼고 있는 이 글은 일차적으로 뇌의 특성화된 기능을 강조하는 뇌기반 기독교교육 모형들을 검토했다. 계속해서기존 모형들의 대안이 될 수 있는 신경과학의 주요 논제들... -
SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation
Rosa Gagliardi, Silvia Llambí, M. Victoria Arruga 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 4 273-280 (8 pages)
The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which animals express modified proteins or genetic sequences responsible for adverse effects associated with a drug. Among the genetic variations that have been investigated in dogs, the multidrug resistance gene (MDR) is the best studied. However, other genes such as CYP1A2 and... -
Dehydroepiandrosterone and cortisol concentrations in the cerebrospinal fluid of dogs
Paolo Mongillo , Marco Bernardini , Elisa Prana , Federica Balducci , Gianfranco Gabai , Lieta Marinelli 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2017, 제 57권 제 1호 8 47-50 (4 pages)
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삼정환의 랫드를 이용한 90일 반복 경구투여 독성시험
김민지(Min-Jee Kim), 이명종(Myeong-Jong Lee), 김호준(Hojun Kim) 한방비만학회 대한한방비만학회지 14 Pages
한방비만학회 대한한방비만학회지 2018, 제 18권 제 1호 5 36-49 (14 pages)


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