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Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model
Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 15 245-251 (7 pages)
on periodontitis. ALH-L1005 was obtained from horse chestnut leaf and its MMP inhibitory activities estimated. Periodontitis was induced in beagles assigned to 4 groups and medicated for 6 weeks: low dose test (LT; ALH-L1005, 100 mg/kg/day), high dose test (HT; ALH-L1005, 200 mg/kg/day), positive control (PC; doxycycline, 10 mg/kg/day), or negative control (NC; placebo). Before and after administration, clinical indices of the teeth and MMP quantity in gingival tissues using zymography were... -
A modified method for inducing periodontitis in dogs using a silk-wire twisted ligature
Se Eun Kim, Eui Ri Lee, Yesran Lee, Manbok Jeong, Young Woo Park, Jae Sang Ahn, Jeong Taek Ahn, Kangmoon Seo* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 11 193-197 (5 pages)
modified silk ligature twisted with wire for inducing advanced periodontitis. Periodontitis was induced in five premolars and one molar of 20 healthy dogs over a 60-day period. The dogs were divided into four groups according to the ligature- inducing materials used: soft moistened food only, wire ligature (WL), silk ligature (SL) and twisted ligature with silk and wire (SWL). Periodontal indices were recorded, and dental radiographs were taken before and after 60 days of ligation. The ligatures... -
Association Study Between Genetic Polymorph isms in Interleukin-1 Gene Family and Adult Periodontitis in Korean
Kang. ByungYong, Kang. Chin Yang, Lee. Kang Oh 한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 7 Pages
한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 2004, Vol.20 No.4 299-305 (7 pages)
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Sensitization of Periodontitis Disease Causing Bacteria by Low Power He-Ne Laser Radiation
Satsangi. Akash Tripathi, Mathur. Manish, Saxena. Parul, Prasad. Guru, Shrivastava. Jitendra Nath, Shrivastava. Jenendra Nath, Roy. Su 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 5 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 2004, Vol.11 No.2 55-59 (5 pages)
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Interrelationship of Matrix Metalloproteinase and $TNF-{alpha}$ in Human Gingiva with Chronic Periodontitis associated to Type 2 Diabetes Mellitus
김도훈, 박의균, 신홍인, 조제열, 서조영, 이재목, Kim. Doe-Heun, Park. Eei-Kyun, Shin. Hong-In, Cho. Je-Yeol, Suh. Jo-Young, Lee. Jae-Mok 대한치주과학회 대한치주과학회지 17 Pages
대한치주과학회 대한치주과학회지 2006, Vol.36 No.2 409-425 (17 pages)
치주질환의 병원균은 세포벽의 항원에 의하여 조직내 존재하는 mononuclear phagocytes가 활성화되어 cytokine들이 생성됨 으로써 치주 결체조직의 파괴를 진행시킨다. 이런 관련된 cytokine들은 순차적으로 상주하는 치은세포 및 대식세포가 Matrix metalloproteinase 합성을 하도록 유도하여 조직파괴를 시작한다. 이들 Matrix metalloproteinase중 MMP-2, MMP-9 (Gelatinase A,B)는 type IV collagen 및 변성된 interstitial collagen을 파괴하며 치주환자의 치은 열구액, 치은조직, 타액 네에서 높게 보고 되어왔다. 당뇨병은...


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