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Normal clinical electroretinography parameters for poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew
Metita Sussadee, Janjira Phavaphutanon, Kornchai Kornkaewrat, Aree Thayananuphat 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 9 67-74 (8 pages)
ridgeback, and Thai Bangkaew. Standard ERG findings were bilaterally recorded using a handheld multi-species ERG unit with an ERG-jet lens electrode for 28 dogs under preanesthesia with diazepam, anesthesia with propofol, and anesthesia maintenance with isoflurane. There were significant differences in the mean values of ERG amplitudes and implicit times among the four dog breeds (p＜ 0.05) except for the b-wave implicit time of the photopic 30 Hz flicker response with... -
Electroretinography recordings using a light emitting diode active corneal electrode in healthy beagle dogs
Yoshiki Itoh, Seiya Maehara, Norihiko Itoh*, Kazuto Yamashita, Yasuharu Izumisawa 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 11 77-84 (8 pages)
Electroretinography (ERG) is a well-established diagnostic procedure for objectively evaluating retinal function. In this study, ERG in beagle dogs, which are a popular experimental animal, was performed to determine the normal range of ERG variables and assess differences between the left and right eyes. ERG findings including rod, combined rod-cone, single-flash cone, and 30-Hz flicker responses were recorded with an LED-electrode in 43 sedated beagle dogs. The subjects were divided into young... -
The normal electroretinogram in adult healthy Shih Tzu dogs using the HMsERG
June-sub Lee, Kyung-hee Kim, Ha-young Jang, Bora Lee, Joon Young Kim, Soon-wuk Jeong* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 9 233-238 (6 pages)
Electroretinography (ERG) is a reliable diagnostic tool for the diagnosis of retinal disease. It measures electric potentials occurring in the retina in response to light stimulation. In this study, we examined the normal electroretinogram using the Handheld Multispecies ERG (HMsERG) in Shih Tzu dogs. ERG recordings were performed in twelve eyes of six healthy Shih Tzu dogs. Dogs were anesthetized with a combination of medetomidine and ketamine. Proparacaine eye drops were also applied as a... -
The determination of dark adaptation time using electroretinography in conscious Miniature Schnauzer dogs
Hyung-Ah Yu, Man-Bok Jeong, Shin-Ae Park, Won-Tae Kim, Se-Eun Kim, Je-Min Chae, Na-Young Yi, Kang-Moon Seo* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 14 409-414 (6 pages)
a contact lens electrode and a built-in light source (LED-electrode). The ERG recordings were performed on nine healthy Miniature Schnauzer dogs. The bilateral ERG's at seven different dark adaptation times at an intensity of 2.5 cdㆍs/m² was performed. Signal averaging (4 flashes of light stimuli) was adopted to reduce electrophysiologic noise. As the dark adaptation time increased, a significant increase in the mean a-wave amplitudes was observed in comparison to base-line levels up to 10... -
Music-Centered Integrated Lesson Plan Based on IB PYP
Sung-Ji Kim, Euna Choi 한국음악교육학회 음악교육연구 20 Pages
한국음악교육학회 음악교육연구 2022, 제 51권 제 2호 1 1-20 (20 pages)
The purpose of this study is to design music-centered integrated lessons based on the International Baccalaureate Primary Years Programme (IB PYP). For this purpose, first, the characteristics of IB PYP were examined, and the scope and sequence, and learning contents on music subject of IB PYP were compared with those of Korea National Curriculum. Second, based on this analysis, the music-centered integrated lessons based on transdisciplinary themes were designed in a spiral curriculum. The... -
MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation
SeongmiLee, SeungTackOh, HaJinJeong, SokCheonPak, Hi-JoonPark, JongpilKim, Hyun-seokCho, SongheeJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 7 625-632 (8 pages)
Familial Parkinson’s disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this study, we developed a new PD model in the transgenic mice expressing mutant hemizygous (hemi) or homozygous (homo) A53T α-synuclein (α-syn Tg) and their wildtype (WT) littermates by treatment with sub-toxic (10 mg/kg, i.p., daily for 5 days) or toxic (30 mg/kg, i.p., daily for 5... -
Advanced Glycation End Products and Diabetic Complications
VarunParkashSingh, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 1 1-14 (14 pages)
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy, neuropathy, cardiomyopathy along with some other diseases such as rheumatoid arthritis, osteoporosis and aging. Glycation of proteins interferes with... -
Electrophysiological and Histologic Evaluation of the Time Course of Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa
SeolAJae, KunNoAhn, JiYoungKim, JeHoonSeo, HyongKyuKim, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 8 229-235 (7 pages)
Among several animal models of retinitis pigmentosa (RP), the more recently developed rd10 mouse with later onset and slower rate of retinal degeneration than rd1 mouse is a more suitable model for testing therapeutic modalities. We therefore investigated the time course of retinal degeneration in rd10 mice before adopting this model in our interventional studies. Electroretinogram (ERG) recordings were carried out in postnatal weeks (PW) 3∼5 rd10 (n=23) and wild-type (wt) mice (n=26). We... -
Microarray Analysis of Differentially Expressed Genes in the Brains of Tubby Mice
JeongHoLee, ChulHoonKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 4 91-98 (8 pages)
The tubby mouse is characterized by progressive retinal and cochlear degeneration and late-onset obesity. These phenotypes are caused by a loss-of-function mutation in the tub gene and are shared with several human syndromes, suggesting the importance of tubby protein in central nervous system (CNS) functioning. Although evidence suggests that tubby may act as a transcription factor mediating G-protein coupled receptor (GPCR) signaling, any downstream gene regulated by tubby has yet to be...
