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- PREVENTIVE NUTRITION AND FOOD SCIENCE(1)
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- 임상약리학회지= THE JOURNAL OF KOREAN SOCIETY FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS(1)
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Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis
Ji-young Jung, Eui-hwa Nam, Seol-hee Park, Seung-hee Han, Cheol-yong Hwang* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 12 199-205 (7 pages)
(TEWL), skin hydration, pruritus index for canine atopic dermatitis (PICAD) scores, and canine atopic dermatitis extent and severity index (CADESI) scores of all dogs were evaluated. Skin samples from five dogs were also examined with transmission electron microscopy (TEM) using ruthenium tetroxide. TEWL, PICAD, and CADESI values decreased (p < 0.05) and skin hydration increased dramatically over time (p < 0.05). Electron micrographs showed that the skin barrier of all five dogs was partially... -
Evaluation of the effect of a 0.0584% hydrocortisone aceponate spray on clinical signs and skin barrier function in dogs with atopic dermatitis
Eui-Hwa Nam, Seol-Hee Park, Ji-Young Jung, Seung-Hee Han, Hwa-Young Youn, Jun-Seok Chae, Cheol-Yong Hwang* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 10 187-191 (5 pages)
The purpose of this study was to evaluate the effects of a topical spray containing 0.0584% hydrocortisone aceponate (HCA) on canine atopic dermatitis (CAD) and to evaluate the skin barrier function during the treatment of CAD. Twenty-one dogs that fulfilled the diagnostic criteria for CAD were included in this study. The HCA spray was applied once a day to the lesions of all dogs for 7 or 14 days. Clinical assessment was performed before (day 0) and after treatment (day 14), and clinical... -
Histologic morphology and involucrin, filaggrin, and keratin expression in normal canine skin from dogs of different breeds and coat types
Sirin Theerawatanasirikul, Gunnaporn Suriyaphol, Roongroje Thanawongnuwech, Achariya Sailasuta* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 7 163-170 (8 pages)
The purpose of this study was to measure the thickness of canine epidermis at various anatomical sites according to localization of cornified envelopes (involucrin and filaggrin), keratins (keratin 10, 5), and their mRNA expression. This was done in the skin of five breeds of dogs including seven poodles, six golden retrievers, six Shih Tzus, four pugs, and four Labrador retrievers. Epidermal thickness of the stratum corneum and nucleated epidermal layer was significantly different. The greatest... -
Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans
YoungOhShin, Jeong-BeomLee, Jeong-HoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 7 499-505 (7 pages)
The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland... -
Seasonal Acclimatization in Summer versus Winter to Changes in the Sweating Response during Passive Heating in Korean Young Adult Men
Jeong-BeomLee, Tae-WookKim, Young-KiMin, Hun-MoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 2 9-14 (6 pages)
We investigated the sweating response during passive heating (partial submersion up to the umbilical line in 42±0.5oC water, 30 min) after summer and winter seasonal acclimatization (SA). Testing was performed in July during the summer, 2011 [summer-SA; temp, 25.6±1.8oC; relative humidity (RH), 82.1±8.2%] and in January during the winter, 2012 (winter-SA; temp, −2.7±2.9oC; RH, 65.0±13.1%) in Cheonan (126o52'N, 33.38'E), Republic of Korea. All experiments were carried out in an... -
Effect of the Heat-exposure on Peripheral Sudomotor Activity Including the Density of Active Sweat Glands and Single Sweat Gland Output
Jeong-BeomLee, Tae-WookKim, Young-OhShin, Young-KiMin, Hun-MoYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 4 273-278 (6 pages)
Tropical inhabitants are able to tolerate heat through permanent residence in hot and often humid tropical climates. The goal of this study was to clarify the peripheral mechanisms involved in thermal sweating pre and post exposure (heat-acclimatization over 10 days) by studying the sweating responses to acetylcholine (ACh), a primary neurotransmitter of sudomotor activity, in healthy subjects (n=12). Ten percent ACh was administered on the inner forearm skin for iontophoresis. Quantitative... -
Heat Acclimatization in Hot Summer for Ten Weeks Suppress the Sensitivity of Sweating in Response to Iontophoretically-administered Acetylcholine
Jeong-BeomLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 10 349-356 (8 pages)
To determine the peripheral mechanisms involved in thermal sweating during the hot summers in July before acclimatization and after acclimatization in September, we evaluated the sweating response of healthy subjects (n=10) to acetylcholine (ACh), a primary neurotransmitter involved in peripheral sudomotor sensitivity. The quantitative sudomotor axon reflex test (QSART) measures sympathetic C fiber function after iontophoresed ACh evokes a measurable reliable sweat response. The QSART, at 2 mA... -
여드름 치료 효과에 따른 수분도 변화
남희수, 김경은, 김민신 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 10 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2017, 제 7권 제 6호 34 371-380 (10 pages)
본 연구는 문제성 피부 중 하나인 여드름 피부를 대상으로 메디칼 스킨케어 치료 후 수분도 변화 를 알아보았으며 그 결과는 다음과 같다. 치료효과에 따른 수분도 변화에서는 KAGS등급 2단계이상 호전된 그룹에서 수분도의 의미 있는 증가가 보였고 이는 여드름의 호전에 의해 개선된 피부장벽기 능으로 인해 피부 수분량이 증가되었기 때문으로 보인다. 다음으로 여드름 치료 횟수에 따른 수분도 변화에서는 3∼4회, 5∼6회, 7회 이상의 세 그룹으로 나누어 측정하였으나, 횟수에 따른 수분도의 변 화는 유의미한 결과가 나타나지... -
백차 열수추출물의 자외선 조사에 의한 피부염증 및 피부장벽손상 완화 효과
이경옥, 김영철, 장병수, Lee. Kyung-Ok, Kim. Young-Chul, Chang. Byung-Soo 한국현미경학회 한국현미경학회지 8 Pages
한국현미경학회 한국현미경학회지 2011, Vol.41 No.3 197-204 (8 pages)
각각 190, 207, 225% 유의하게(p<0.001) 높았다. 경표피수분 손실량(transepidermal water loss, TEWL) 측정에서, 실험 4주후 C군에 비해 PC, E1, E2군은 각각 61, 79, 85% 유의하게(p<0.001) 낮았다. 조직학적 관찰에서, C군에 비해 E1, E2군은 표피층과 진피층의 비후, 비만세포수와 탈과립 정도가 현저하게 경감되었다. 이상의 연구결과를 종합할 때, hairless 마우스를 이용한in vivo 실험에서 백차 열수추출물 경피 도포는 자외선 조사로 인해 유발된 피부장벽 손상 및 염증 반응에 상당한 개선 효과가 있음을 확인하였다. -
자초(Lithospermum erythrorhizon) 추출물이 UVB로 조사된 생쥐 피부에 미치는 영향
송선영, Song. Seon-Young 한국현미경학회 한국현미경학회지 10 Pages
한국현미경학회 한국현미경학회지 2008, Vol.38 No.3 195-204 (10 pages)
24시간, 48시간, 72시간, 120시간, 168시간의 시간대별로 관찰하였다. 경표피수분손실량을 측정한 결과, UVB+Le군이 UVB군 보다 시간이 경과함에 따라 TEWL이 감소하였다. 특히 168시간군에서 유의하게 낮게 나타났다(p<0.05). 멜라닌 양 측정 결과, UVB+Le군이 UVB군 보다 낮게 나타났으나 통계학적으로 유의성은 없게 나타났다(p>0.05). 홍반 지수 측정 결과, UVB+Le group 24시간, 48시간, 72시간군에서 UVB group 보다 유의하게 낮게 나타났다(p<0.05). 주사전자현미경적 관찰 결과, UVB group 24시간군에서는 UVB group보다...


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