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Genome-wide Association Study Identified TIMP2 Genetic Variant with Susceptibility to Osteoarthritis
Keam. Bhum-Suk, Hwang. Joo-Yeon, Go. Min-Jin, Heo. Jee-Yeon, Park. Mi-Sun, Lee. Ji-Young, Kim. Nam-Hee, Park. Miey, Oh. Ji-Hee, Kim. Dong 한국유전체학회 Genomics & informatics 6 Pages
한국유전체학회 Genomics & informatics 2011, Vol.9 No.3 121-126 (6 pages)
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이온화 방사선에 의한 TIMP1, TIMP2 유전자 발현 측정
박건구, 진정선, 박기영, 이연희, 김상윤, 노영주, 안승도, 김종훈, 최은경, 장혜숙, Park. Kun-Koo, Jin. Jung Sun, Park. Ki Yong, Lee. Yun Hee, Kim. Sang Yoon, Noh. Young Ju, Ahn. 대한방사선종양학회 대한방사선종양학회지 10 Pages
대한방사선종양학회 대한방사선종양학회지 2001, Vol.19 No.2 171-180 (10 pages)
2 Gy인 경우 모두 $94\%$ 이상 그리고 10 Gy에서는 $73\%$ 이상의 생존 세포를 확인하였다. TIMP1, TIMP2 단백의 basal 농도는 24시간 48시간에서 점점 증가하여 세포에서 계속 합성되어 분비되고 있음을 확인하였다. 2 Gy 조사 후 24시간에서 TIMP2는 HN-1, HN-9 세포주에서 감소하였으나, 10 Gy 조사 후에는 두 세포주에서 모두 증가하여 방사선량에 따라 반응이 달랐고, 방사선조사 후 48시간에는 HN-9 세포주에서는 증가하나 HN-9 세포주에서는 감소하여 세포주에 따라 반응이 달랐다. 그러나 방사선에 의한 TIMP1 발현 변화는... -
Osteogenic Capacity of Osteogenic Matrix Cell Sheet on Poly ε-caprolactone/β-tricalcium Phosphate Scaffolds in Canine Segmental Bone Defect Model
Yong sun Kim, Min young Kuk, Seung Hoon Lee, Da eun Rhew, Ah Young Kim, Wan Hee Kim, Hui Suk Yun, Oh Kyeong Kweon 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 165 224-225 (2 pages)
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Effects of Lanosterol on Porcine Oocytes in vitro Maturation and Subsequent Embryonic Development after Parthenogenetic Activation
Sang hoon Lee, Jun Xue Jin, Crani Khoirinaya, Joon Ho Moon, Eun Jung Park, Geon A Kim, Byeong Chun Lee 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 164 224-224 (1 pages)
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Effect of subcutaneous treatment with human umbilical cord blood-derived multipotent stem cells on peripheral neuropathic pain in rats
MinJuLee, TaeGyoonYoon, MoonkyuKang, HyunJeongKim, KyungSunKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 2 153-160 (8 pages)
In this study, we aim to determine the in vivo effect of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs) on neuropathic pain, using three, principal peripheral neuropathic pain models. Four weeks after hUCBMSC transplantation, we observed significant antinociceptive effect in hUCB-MSC– transplanted rats compared to that in the vehicle-treated control. Spinal cord cells positive for c-fos, CGRP, p-ERK, p-p 38, MMP-9 and MMP 2 were significantly decreased in only CCI... -
Regulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic Mice
ChorongJang, JiHeeLim, CheolWheePark, Young-JinCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 8 299-306 (8 pages)
Calcineurin (CaN) is activated in diabetes and plays a role in glomerular hypertrophy and extracellular matrix (ECM) accumulation. Here, kidneys from diabetic model mice were investigated for the expression of the regulator of CaN 1 (RCAN1) isoform 4 (RCAN1.4) which had been shown to be transcriptionally upregulated by CaN activation. We found the increased immunoreactivity for RCAN1 in the glomerular cells of db/db mice and streptozotocin-induced diabetic mice. In concordance, the expression of...
