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Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats
HwanSooJang, JiYoungKim, SangHeonKim, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 2 147-151 (5 pages)
by a 3-day withdrawal period and then apomorphine (2.5 mg/kg, i.p.) challenge after pretreatment with saline, SCH-23390, or haloperidol on the day of the experiment. EEGs from the frontal and parietal cortices were recorded. On the frontal cortex, apomorphine decreased the power of all the frequency bands in the single treatment group, and increased the theta (4.5∼8 Hz) and alpha (8∼13 Hz) powers in the repeated treatment group. Changes in both groups were reversed to the control values by... -
遠志가 Apomorphine으로 유발된 생쥐의 상동적 행동에 미치는 효과
정인원, 오원근, 김시경, 안종석, 이현선, 신철진, 박주배, 김용식 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 1998, 제 37권 제 6호 29 1317-1324 (8 pages)
遠志의 일차추출물을 대상으로 도파민 효현제인 apomorphine(0.01mg/g)에 의하여 유발된 생쥐의 상동적 행동을 억제하는 정도를 육안관찰법에 의하여 측정하였다. 투여약물은 용량별(0.5mg/g과 5mg/g)로 나누어 억 제효과를 측정하고 이를 haloperidol군 및 대조군과 비교하였으며 각 집단의 표본수는 10마리로 하였다. 결 과: 아포모르린에 의하여 유발된 상동적 행동의 억제 정도는 haloperidol, 遠志 고용량군, 저용량군, 대조군의 순으로 나타났다. 遠志의 일차추출물은 고용량군과 저용량군 모두 대조군에 비하여 의미있게 상동적... -
일즉 폭질체 파괴 백서에서 Apomorphine의 회전운동에 미치는 교감신경계의 역할
박근영, 유상은, 은홍배 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1993, 제 32권 제 5호 17 767-775 (9 pages)
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Lithium 및 Carbamazepine 이 Apomorphine으로 유도된 일측 흑질체 파괴 백서의 회전운동에 미치는 영향
손희섭, 유상은, 은홍배 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1995, 제 34권 제 2호 22 564-572 (9 pages)
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Time Courses of pCREB Expression after Dopaminergic Stimulation by Apomorphine in Mouse Brain
Jang. Choon-Gon, Lee. Seok-Yong, Lee. Han-Kyu, Suh. Hong-Won, Song. Dong-Keun 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2002, Vol.25 No.3 370-374 (5 pages)
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NMDA-type Glutamatergic Modulation in Dopaminergic Activation Measured by Apomorphine-Induced Cage Climbing Behaviors
Jang. Choon-Gon, Lee. Seok-Yong 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2001, Vol.24 No.6 613-617 (5 pages)
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Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration
ZhenzhenHu, Eun-HyeOh, YeonBokChung, JinTaeHong, Ki-WanOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 2 89-97 (9 pages)
The aim of this study was to investigate the involvement of dopaminergic receptors (DR) in behavioral sensitization, as measured by locomotor activity, and the over-expression of cocaine- and amphetamine-regulated transcript (CART) peptides after repeated administration of cocaine in mice. Repeated administrations of cocaine induced behavioral sensitization and CART over-expression in mice. The levels of striatal CART mRNA were significantly increased on the 3rd day. CART peptides were... -
Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat Model
Myoung-AeChoe, Byung-SooKoo, GyeongJuAn, SongheeJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 3 305-312 (8 pages)
This study was to determine the effect of exercise on the recovery of dopaminergic neuron loss and muscle atrophy in 6-OHDA-induced hemi Parkinson's disease model. Exercise was loaded twice per day for 30 minutes each time, at 5 days after 6-OHDA lesioning and continued for 16 days using a treadmill. Exercise significantly increased the number of tyrosine hydroxylase positive neuron in the lesioned substantia nigra and the expression level of tyrosine hydroxylase in the striatum compared with... -
Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats
Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)
The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated...


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