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전체 선택해제
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본문검색 결과만 보기
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Curcumin Attenuates Glial Cell Activation But Cannot Suppress Hippocampal CA3 Neuronal Cell Death in i.c.v. Kanic Acid Injection Model
JaeyoungCho, Pil-JaeKong, WanjooChun, Yeo-OkMoon, Yee-TaePark, So-YoungLim, Sung-SooKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 3 307-310 (4 pages)
(ROS) play a pivotal role in the pathogenesis of excitotoxic death by KA. Curcumin has been known to possess anti-oxidative and anti-inflammatory activities. In this study, the effects of curcumin on KA induced hippocampal cell death, reactive gliosis and biochemical changes in reactive glia were investigated by immunohistochemical methods. Our data demonstrated that curcumin attenuated KA-induced astroglial and microglial activation although it did not protect KA-induced hippocampal cell death. -
신경세포가 별아교세포의 아교섬유성 산단백질 표현에 미치는 영향 Effect of Glial-neuronal Cell Co-culture on GFAP Expression of Astrocytes
배형미, 박정선, 연동수, HyungmiBae, JungsunPark, DongsooYeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 7 285-296 (12 pages)
their reactive form, the hallmark of which is an increase in glial fibrillary acidic protein (GFAP), the major intermediate filament protein of their cell type. The overall glial response after brain injury is referred to as reactive gliosis. Glial-neuronal interaction is important for neuronal migration, neurite outgrowth and axonal guidance during ontogenic development. Although much attention has been given to glial regulation of neuronal development and regeneration, evidences also suggest a... -
귀비탕이 Glutamate에 의한 C6 Glial Cell의 Apoptosis에 미치는 영향
강익현, 이인, 한상혁, 문병순 대한한의학회 大韓韓醫學會誌 13 Pages
대한한의학회 大韓韓醫學會誌 2001, Vol.22 No.4 45-57 (13 pages)
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Protein Kinases as Pharmacological Targets for the Reduction of Interleukin-1 Expression in Lipopolysaccaride-Activated Primary Glial Cell
Sun. Hu-Nan, Fang. Wan, Jin. Mei-Hua, Han. Ying-Hao, Kim. Sun-Uk, Lee. Sang-Han, Kim. Nam-Soon, Kim. Cheol-Hee, Lee. Dong-Seok 대한의생명과학회 Journal of experimental & biomedical sciences 8 Pages
대한의생명과학회 Journal of experimental & biomedical sciences 2004, Vol.10 No.4 325-332 (8 pages)
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소풍탕(疎風湯)이 Glutamate에 의한 C6 Glial Cell의 Apoptosis에 미치는 영향
정승원, 최철원, 김봉상, 문병순, Jeong. Seung-Won, Choi. Chul-Won, Kim. Bong-Sang, Moon. Byung-Soon 대한동의생리학회 동의생리병리학회지 8 Pages
대한동의생리학회 동의생리병리학회지 2008, Vol.22 No.6 1423-1430 (8 pages)
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Genomic Organization and Promoter Characterization of the Murine Glial Cell-derived Neurotrophic Factor Inducible Transcription Factor (mGIF) Gene
김옥수, 김용만, 김남영, 이어진, 장민경, 이동근, 이상현, Kim. Ok-Soo, Kim. Yong-Man, Kim. Nam-Young, Lee. Eo-Jin, Jang. Min-Kyung, Lee. Dong-Geun, Lee. Sang-Hyeon 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2007, Vol.17 No.2 167-173 (7 pages)
생쥐 신경교세포 유래 신경영양인자 유도성 전사인자(mGIF)의 발현조절에 필요한 전사기작을 연구하기 위하여 mGIF cDNA를 탐침자로 이용하여 genomic clone을 분리하였다. 전체 유전자 13-kb 영역 중 전사개시점에서 4-kb 상류영역의 유전자 서열을 파악한 결과, 프로모터 영역에서 TATA box와 CAAT box는 발견할 수 없었으며 G+C content는 높은 것으로 나타났고 여러 개의 Sp1 전사인자 결합영역이 있었다. 또한 mGIF 유전자는 AP2 결합에 필요한 보존적 영역이 있었다. mGIF 유전자의 프로모터 영역의 단편들을 프로모터가 없는... -
Transcriptional Regulation of the Glial Cell-Specific JC Virus by p53
Kim. Hee-Sun, Woo. Moom-Sook 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2002, Vol.25 No.2 208-213 (6 pages)
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Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment
Dae Young Yoo, Woosuk Kim, Dae Won Kim, Sung Min Nam, Hyo Young Jung, Jong Whi Kim, Choong Hyun Lee, Jung Hoon Choi, Moo-Ho Won, 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 3 27-33 (7 pages)
a day to both groups of mice. We measured cell proliferation and neuroblast differentiation in the subgranular zone of the dentate gyrus using Ki67 and doublecortin (DCX), respectively, as markers. In addition, we monitored the effects of RSG on the levels of DCX and brain-derived neurotrophic factor (BDNF) in hippocampal homogenates. At 8 weeks after the LFD feeding, the numbers of Ki67- and DCX-positive cells as well as hippocampal levels of DCX and BDNF were significantly decreased in the... -
Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development
Joong-Sun Kim, Juhwan Kim, Yujin Kim, Miyoung Yang, Hyosun Jang, Sungwoon Kang, Jong-Choon Kim, Sung-Ho Kim, Taekyun Shin*, Chan 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 1호 1 1-6 (6 pages)
Intermediate filaments, including nestin and glial fibrillary acidic protein (GFAP), are important for the brain to accommodate neural activities and changes during development. The present study examined the temporal changes of nestin and GFAP protein levels in the postnatal development of the mouse hippocampus. Mouse hippocampi were sampled on postnatal day (PND) 1, 3, 6, 18, and 48. Western blot analysis showed that nestin expression was high at PND 1 and markedly decreased until PND 18....
