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Effect of Tectorigenin Obtained from Pueraria thunbergiana Flowers on Phase I and -II Enzyme Activities in the Streptozotocin-induced Diabetic Rat
Choi. Jong-Won, Shin. Myung-Hee, Park. Kun-Young, Lee. Kyung-Tae, Jung. Hyun-Ju, Park. Hee-Juhn 한국생약학회 Natural product sciences 6 Pages
한국생약학회 Natural product sciences 2003, Vol.9 No.4 235-240 (6 pages)
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Enhancement of Phase II and Antioxidant Enzymes in Mice by Soybeans Fermentation with Basidiomycetes
Shon. Yun-Hee, Kim. So-Yeun, Lee. Jae-Sung, Nam. Kyung-Soo 한국미생물생명공학회 Journal of microbiology and biotechnology 7 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2000, Vol.10 No.6 851-857 (7 pages)
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감궁탕 처방 중 천궁의 생체에서 Phase II 효소 유도 효과
한상훈, 손윤희, 김혁, 이희순, 박인경, 남경수, 김철호, 임종국, Han. Sang-Hun, Shon. Yun-Hee, Kim. Hyuck, Lee. Hee-Soon, Park. In-Kyung, Nam. Kyung-Soo, Kim. Cheorl-Ho 경락경혈학회 대한경락경혈학회지 6 Pages
경락경혈학회 대한경락경혈학회지 2003, Vol.20 No.1 65-70 (6 pages)
천궁약침액을 7일간 중완혈, 간수혈 및 임의혈에 투여한 후 마우스의 간에서 유도되는 phase II enzyme 유도 효과를 살펴본 결과 마우스의 간 조직에서 Phase II 효소의 활성이 증가된 것으로 보아 천궁약침액은 외부물질이나 대사산물에 의해 일어날 수 있는 암발생 억제 효과가 있는 것으로 사료된다. -
애엽(艾葉) 약침액(藥鍼液)에 의한 Phase II 효소 활성 유도
윤성묵, 조경희, 손윤희, 남경수, 임종국, Yoon. Sung-Mook, Cho. Kyoung-Hee, Shon. Yun-Hee, Nam. Kyung-Soo, Lim. Jong-Kook 경락경혈학회 대한경락경혈학회지 9 Pages
경락경혈학회 대한경락경혈학회지 2001, Vol.18 No.1 1-9 (9 pages)
tumor cell을 이식하여 복수암이 유발된 생쥐의 EATC 성장을 살펴 본 결과 약침액을 투여한 생쥐의 EATC의 성장이 크게 억제되었으며, 복수암이 유발된 생쥐의 비장 무게가 대조군에 비해 증가하였다. 또한 장기간의 관찰에 의해서도 복수암 세포의 성장 저해에 의해 생쥐의 체중변화율은 대조군에 비해 크게 억제되었으며 수명 연장 효과가 나타났다. 이와같은 생체에서의 암예방 효과를 in vitro 상에서 그 기전을 살펴본 결과 애엽 약침액은 phase II detoxification 효소인 QR의 생성을 유도하고 GSH 함량을 증가시켜서 암예방 효과를... -
Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay
Hyuk-Mi Lee, Sung-Ok Song, Sang-Ho Cha, Sung-Bok Wee, Karyn Bischoff, Sung-Won Park, Seong-Wan Son, Hwan-Goo Kang*, Myung-Haing 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 5 143-150 (8 pages)
Monoclonal antibody (mAb, NVRQS-DON) against deoxynivalenol (DON) was prepared. DON-Ag coated enzyme linked immunosorbent assay (ELISA) and DON-Ab coated ELISA were prepared by coating the DON-BSA and DON mAb. Quantitative DON calculation ranged from 50 to 4,000 ng/mL for DON-Ab coated ELISA and from 25 to 500 ng/mL for DON-Ag coated ELISA. 50% of inhibitory concentration values of DON, HT-2, 15-acetyl-DON, and nivalenol were 23.44, 22,545, 5,518 and 5,976 ng/mL based on the DON-Ab coated ELISA.... -
Molecular differentiation of Korean Newcastle disease virus (NDV) by restriction enzyme analysis and pathotype-specific RT-PCR
HyukJoonKwon, SunHeeCho, SunJoongKim 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2006, 제 46권 제 4호 10 371-379 (9 pages)
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Role of Angiotensin II and Nitric Oxide in the Rat Paraventricular Nucleus
Eun-KyoungYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 6 41-46 (6 pages)
To investigate the mutual relationship between angiotensin II (Ang II) and nitric oxide (NO) in paraventricular nucleus (PVN), Ang II receptor type Ia (AT1A), type Ib (AT1B), endothelial constitutive nitric oxide synthase (ecNOS), and neuronal constitutive nitric oxide synthase (ncNOS) mRNA levels of rat PVN were measured after unilateral carotid artery ligation. AT1A and AT1B mRNA levels were markedly elevated 6 hrs after unilateral carotid artery ligation. Losartan injection (10μg/0.3μl)... -
Tissue-Specific Regulation of Angiotensinogen and Angiotensin II Receptor Gene Expression in Deoxycorticosterone Acetate-Salt Hypertensive Rats
JongUnLeeMiRaAn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 9 315-320 (6 pages)
of renin, angiotensinogen and angiotensin II receptor genes in the kidney and liver was determined by Northern blot analysis in rats which were made DOCA-salt hypertensive over the period of 2 or 4 weeks. Along with the hypertension, renin mRNA was decreased in the remnant kidney. The expression of angiotensinogen gene was not significantly altered in the kidney, but was significantly decreased in the liver. The expression of angiotensin II receptor gene was increased in the kidney, while it... -
Simultaneous HPLC Analysis of Arachidonic Acid Metabolites in Biological Samples with Simple Solid Phase Extraction
Hyung-GunKim, Young-NaHuh, Kun-SukPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 15 779-786 (8 pages)
A reversed-phase high-performance liquid chromatogrphy (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram level. This procedure makes it possible to extract complex mixtures of eicosanoids efficiently with a single step and to analyze them simultaneously by RP-HPLC from biological samples using octadesylsilyl silica extraction column and PGB2 as an internal... -
Synthesis and physicochemical characterization of NixZnx- FeO₂O₄/MWCNT nanostructures as enzyme mimetics with peroxidase-like catalytic activity
Navvabeh Salarizadeh, Minoo Sadri, Hassan Hosseini, Reza. H. Sajedi 한국탄소학회 Carbon Letters 8 Pages
한국탄소학회 Carbon Letters 2017, Vol.24 14 103-110 (8 pages)
physicochemical properties, but the Ni0.5Zn0.5Fe2O4/MWCNT nanocatalyst was more appropriate than the Ni0.25Zn0.25Fe2O4/MWCNT nanocatalyst in terms of the magnetic properties and catalytic activity. The optimum peroxidase-like activity of the nanocatalysts was obtained at pH 3.0. The Ni0.5Zn0.5Fe2O4/MWCNT nanocatalyst exhibited a good peroxidase-like activity. These magnetic nanocatalysts can be suitable candidates for future enzyme-based applications such as the detection of glucose and H2O2.


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