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Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
Yun-Hsia Hsiao, Charles Chen, Ton Willemse 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 14 549-553 (5 pages)
This study was conducted to evaluate the effects of cetirizine in dogs with atopic dermatitis (AD) while fulfilling Favrot’s diagnostic clinical criteria. Dogs received either 3 mg/kg cetirizine (n = 27), or a placebo (n = 23) orally once daily for 14 days in a randomized, double blind, placebo-controlled study, without concomitant medication. The effects were evaluated using a pruritus visual analog scale at the start (day 0) and at day 14. After 14 days, cetirizine clearly had no effect on... -
Common allergens of atopic dermatitis in dogs: comparative findings based on intradermal tests
Ha-Jung Kim, Min-Hee Kang, Hee-Myung Park* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 13 287-290 (4 pages)
Intradermal tests were performed on 58 dogs diagnosed with atopic dermatitis from 2004∼2008 at the Veterinary Medical Teaching Hospital of Konkuk University, Korea. To compare the allergen distribution observed in the present investigation to the results from other studies conducted in Korea and elsewhere, the allergens were grouped according to their kinds. There was no significant difference in gender distribution among the dogs. The most common breeds among the 58 dogs were Maltese (n =... -
Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice
Soon-Hee Lee, Yong Heo, Young-Chul Kim, * 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 1호 6 35-41 (7 pages)
Historically, German chamomile (GC) oil has been used for treatment of skin disorders. BALB/c mice were sensitized twice a week with 100 μL of 1% 2,4-dinitrochlorobenzene (DNCB) and challenged twice the following week with 100 μL of 0.2% DNCB for atopic dermatitis induction. Thereafter, 3% GC oil was applied daily (70 μL, 6 times week) on the dorsal skin for 4 weeks. Saline or jojoba oil was used for the control mice. Blood was collected after second DNCB challenge, and at 2 and 4 weeks after... -
Allergens Causing Atopic Diseases in Canine
Hwa-Young Youn, Hyung-Seok Kang, Dong-Ha Bhang, Min-Kue Kim, Cheol-Yong Hwang and Hong-Ryul Han 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 12 335-341 (7 pages)
Canine atopic skin disease is seasonal or sometimes non-seasonal immune-mediated skin disease which occurs commonly in Korea. The definite clinical sign is systemic pruritus, especially on periocular parts, external ear, interdigit spaces and lateral flank. For diagnosis of this dermatitis, complete history taking followed by intradermal skin test and serum in vitro IgE test needs to be performed. Allergen selection for the diagnosis and treatment of atopic dermatitis should be varied... -
Identification of Differentially Expressed Genes in Murine Hippocampus by Modulation of Nitric Oxide in Kainic Acid-induced Neurotoxic Animal Model
YoAhnSuh, OMinKwon, SoYoungYim, HeeJaeLee, Sung-SooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.4 3 149-154 (6 pages)
Kainic acid (KA) causes neurodegeneration, but no consensus has been reached concerning its mechanism. Nitric oxide may be a regulator of the mechanism. We identified differentially expressed genes in the hippocampus of mice treated with kainic acid, together with or without L-NAME, a nonselective nitric oxide synthase inhibitor, using a new differential display PCR method based on annealing control primers. Eight genes were identified, including clathrin light polypeptide, TATA element... -
척수신경손상에 대한 흥분성 아미노산 수용체 길항제의 효과에 대한연구
김종근(Jong Keun Kim) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1995, 제 31권 제 1호 1 1-10 (10 pages)
외상성 척추신경손상후에 병리조직학적 변화가 서서히 일어나며, 손상부위가 안정화되는데 걸리는 시간이 길어서 2차 손상과정이 최초의 기계적 손상을 악화시킴이 오래전부터 잘 알려져 있다. 이러한 2차 손상과정의 개입은 척추신경손상을 약리학적으로 조절하는 시도에 대한 논리적 배경을 제공하고 있다. 흥분성 아미노산은 척수의 정상기능뿐아니라 허혈성 및 외상성 손상에 의한 세포사망에 관여함이 알려져 있어 외상성 척수손상의 2차 손상과정에 이 흥분성 아미노산 수용체가 관여할 것임이 시사되고 있다. Dextrorphan은... -
Voltage-Dependent Ionic Currents and Their Regulation by GTP and Phorbol Ester in the Unfertilized Eggs of Mouse and Hamster
Kim, Ik-Hyun, Kim, Yang-Mi, Haan, Jae-Hee, Park, Choon-Ok, Hong, Seong-Geun 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 9 93-106 (14 pages)
The present study was performed to investigate the properties of ionic currents elicited by voltage pulses in the unfertilized eggs of mouse and hamster by using the whole cell voltage clamp techniques and to find out if there are any differences in properties between eggs of the two rodents. In addition, the modulatory effect of G proteins and protein kinase C (PKC) on the ionic channels were observed. The inward current in hamster eggs was shown to be due to Ca2+ current (ica)). The current... -
Analysis of Allergy Symptoms and Quality of Life among University Students with Allergic Rhinitis
Mi Ryeong Song, Joon Soo Park 한국기초간호학회 Journal of Korean Biological Nursing Science 8 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2013, Volume 15, No 4 13 264-271 (8 pages)
Purpose: The purpose of this study was to analyze the symptoms of allergic rhinitis among university students and assess their quality of life (QOL) in order to establish an effective program for university students with allergic rhinitis. Methods: The data were collected in May, 2012 in a university school health center. The collected data were analyzed in terms of frequency, percentage and mean for the symptom types and QOL among 131 university students with allergic rhinitis. An independent... -
개 피부에서 Histamine에 의한 팽진과 발적에 대한 loratadine, cetirizine과 terfenadine의 억제효과
Jeong. A-Young, Jeong. Hyo-Hoon, Heo. Woo-Phil, Eom. Ki-Dong, Jang. Kawng-Ho, Oh. Tae-Ho 한국임상수의학회 Journal of veterinary clinics 5 Pages
한국임상수의학회 Journal of veterinary clinics 2002, Vol.19 No.2 186-190 (5 pages)
아토피성 피부염은 면역계재성 피부질환으로 소양증이 주요 증상이며 이의 치료가 필수적이다. 따라서 개에서 제2세대 항히스타민제의 임상적용을 위해 피부에 히스타민에 의해 유발된 팽진과 발적에 대한 loratadine, cetirizine과 terfenadine의억제 효과를 비교하였다. 3종의 항히스타민제는 대조군에 비해 매우 유의하게 발적반응을 억제하였으며(p<0.01) cetirizine이 다른 제제에 비해 높은 억제효과를 보였다. 3종의 항히스타민제는 팽진 반응을 억제하는 효과를 보였으며 loratadine의 억제효과가 일정하며 지속적이었다.... -
지부자 피부도포가 히스타민 유발 소양감, 홍반, 팽진에 미치는 영향
김정선, 한재복, 황의완, 민병일 대한한의학회 大韓韓醫學會誌 8 Pages
대한한의학회 大韓韓醫學會誌 2003, Vol.24 No.1 133-140 (8 pages)


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