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Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress
Md Jamal Uddin, Eun Seon Pak, Hunjoo Ha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 10 567-575 (9 pages)
such as TNFa, MCP1, iNOS, and ICAM1 in mProx cells were measured using real-time PCR. Data are presented as means±SE, n=4; *p<0.05 vs. control, †p<0.05 vs. LPS. ..PAGE:5 Effect of CO on ER stress-induced AKI Korean J Physiol Pharmacol 2018;22(5):567-575 www.kjpp.net 571 of ER stress. Interestingly, CORM2 significantly decreased LPS- induced p-JNK (Figs. 3A and B) and CHOP (Figs. 3C and D) pro-... of CORM2 (30 mg/kg) effectively prevented LPS-induced oxidative stress and inflammation during AKI in mice. CORM2 treatment also effectively inhibited LPS-induced ER stress in AKI mice. In order to confirm effect of CO on the pathophysiological role of tubular epithelial cells in AKI, we used mProx24 cells. Pretreatment of CORM2 attenuated LPS-induced ER stress, oxidative stress, and inflammation in mProx24 cells. These data suggest that CO therapy may prevent ER stress-mediated AKI. -
Bis is Induced by Oxidative Stress via Activation of HSF1
HyungJaeYoo, Chang-NimIm, Dong-YeYoun, HyeHyeonYun, Jeong-HwaLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 8 403-409 (7 pages)
in cells represents the net effects contributed from the interactions of individual cis-elements and the corresponding trans- acting factors, such as HSF1, Bis or other unknown factors. We, and other groups, have reported that Bis expression is increased by oxidative stress or pro-oxidants, both in vivo and in vitro [20,27,28]. The physiological significance of Bis induction upon PDTC or HNE... of stress, such as heat shock or a proteasome inhibitor via the activation of heat shock factor (HSF)1. We report herein that Bis expression is increased at the transcriptional level in HK-2 kidney tubular cells and A172 glioma cells by exposure to oxidative stress such as H2O2 treatment and oxygen-glucose deprivation, respectively. The pretreatment of HK-2 cells with N-acetyl cysteine, suppressed Bis induction. Furthermore, HSF1 silencing attenuated Bis expression that was induced by H2O2,... -
Low dietary inorganic phosphate affects the lung growth of developing mice
Cheng-Xiong Xu, Hua Jin, Youn-Sun Chung, Ji-Young Shin, Soon-Kyung Hwang, Jung-Taek Kwon, Sung-Jin Park, Eun-Sun Lee, Arash Mina 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 2호 3 105-113 (9 pages)
5 randomly chosen fields per section and determining the percentage of DAB-positive cells per 100 cells at ×400 by the method described by Zhang et al. [32]. Statistical analysis Quantification of the Western blot analysis was performed using the Multi Gauge version 2.02 program (Fujifilm, Japan). All the results are given as means ± SE. The results were analyzed by unpaired Student’s... Inorganic phosphate (Pi) plays a critical role in diverse cellular functions, and regulating the Pi balance is accomplished by sodium-dependent Pi co-transporter (NPT). Pulmonary NPT has recently been identified in mammalian lungs. However, to date, many of the studies that have involved Pi have mainly focused on its effect on bone and kidney. Therefore, current study was performed to discover the potential effects of low Pi on the lung of developing transgenic mice expressing the... -
Continuous straight archwire에 의하여 발생하는 force system의 분석
최광철(Kwang-Chul Choy), 손병화(Byung Hwa Sohn) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 3호 6 281-290 (10 pages)
bracket 에 straight wire가 장착된 경우에만 적용이 가능하다. 반면에 edgewise bracket 은 wire 가 장착된 후 한쪽에 서 deflection 되는 경우 그 stressフ1* bracket 을 통과해 서 다른 쪽으로 전달되지 않는 fixed support의 양상 을 나타내게 된다. 이러한 model 에서 발생하는 force system에 대해서는 1974 년 Burstone이 angulated 표 1. 각종 wire에 대한 relative El, yield moment, 니Itimate moment6'8) ‘ .... Edgewise bracket에 continuous straight archwire를 장착 했을 때 각 bracket에 발생하는 force system은 statically indeterminate system이기 때문에 임상적으로 측정이 어렵다. 이에 본 연구는 linear beam theory를 도입하여 full arch에 straight wire가 장착된 경우 geometry(a/b), 재질, 단면의 모양, interbracket distance에 관계없이 발생 가능한 모든 상태를 설명할 수 있는 식을 유도하고 일례의 분석을 통하여 다음과 같은 결과를 얻었다. 1. Bilateral fixed beam의 양끝에서 발생하는 force system을 알 수 있는 계산식을... -
Physiology of Man under High Pressure
Hong Suk-Ki 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1988, 제 22권 제 2호 1 153-162 (10 pages)
(Section B) the thoracic conductive volume increased during the compression phase of the Hana Kai II dive, strongly implying that the low pressure volume receptors located in the atrium are most likely stimulated and, as a result, that atrial natriuretic peptide (ANP) could be released. Under a variety of +100 0 <( f--<( 1? -100 ;;; .§ u +100 .2 >, \... -
Pathogenicity of Bacillus Strains to Cotton Seedlings and Their Effects on Some Biochemical Components of the Infected Seedlings
Aly A. Aly, Omima M. El-Mahdy, Marian M. Habeb, Abeer Elhakem, Amal A. Asran, Maryan M. Youssef, Heba I. Mohamed, Rania S. Hanafy 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 3 91-101 (11 pages)
spp. were used in the present study (Table 1). The Bacillus strains originated from roots of cotton plants and were ob- tained from the bacterial collection of the Cotton Diseases Research Section, Plant Pathology Research Institute, Ag- ricultural Research Center, Giza, Egypt. Bacterial strains were identified to the species level by standard bacterio- logical tests (Holt et al., 1994)... Pathogenicity of eight Bacillus strains to seedlings of four cotton cultivars was evaluated under greenhouse conditions. Each of the tested cultivars was individually treated with powdered inoculum of each bacterial strain. Untreated seeds were planted as control treatments in autoclaved soil. Effects of the tested strains on levels and activities of some biochemical components of the infected seedlings were also assayed. The biochemical components included total soluble sugars, total soluble... -
Histone Acetylation in Fungal Pathogens of Plants
한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2014, 30권 1호 1 1-9 (9 pages)
debatable and depend on the case. Nonetheless it is possible to expect mechanisms of epigenetic adaptation to host conditions as opposed to genetic adaptation, which will be discussed in the last section of this review. MYST family. The MYST family, which was named after the initials of the founding members, is the largest family of acetyltransferases with diverse biological functions. In t... Acetylation of histone lysine residues occurs in different organisms ranging from yeast to plants and mammals for the regulation of diverse cellular processes. With the identification of enzymes that create or reverse this modification, our understanding on histone acetylation has expanded at an amazing pace during the last two decades. In fungal pathogens of plants, however, the importance of such modification has only just begun to be appreciated in the recent years and there is a dearth of... -
The Relationship Between Addiction to Computers and Smartphones and Carpal Tunnel Syndrome in Average People
Lee Jun-Cheol 한국보건기초의학회 한국보건기초의학회지 7 Pages
한국보건기초의학회 한국보건기초의학회지 2017, Vol.10 No.2 5 60-66 (7 pages)
people to relieve stress from the modern society and expand horizons in interpersonal relations. It was analyzed that 78.0% (37,180,000 people) of the population aged 3 and above were using the internet as of July 2015, and 99.9% of people in their 10s and 20s were using the internet. In 2015, the supply rate of the in- ternet in Korea was 81.8% and that of computers was 81.9% (Korea Inter- net... The objective of this study was to investigate the relationship between computer and smartphone addiction and carpal tunnel syndrome (CTS) in average people. A total of 378 subjects, 126 males and 252 females, were tested on a computer and smartphone addiction scale, a Symptom Severity Scale (SSS), and a Function Status Scale (FSS) for CTS. 49 (12.9%) of the subjects used a computer and 329 (87.1%) were smartphone users. This study showed that among the computer users 23 (46.9%) subjects... -
호주의 보훈정책
박혜란 한국보훈학회 한국보훈학회 학술대회지 22 Pages
한국보훈학회 한국보훈학회 학술대회지 2011 춘계 6 133-154 (22 pages)
for section 143(2) and (3), 144(4), 149, 150. 153(2),156, 158 and 159 공무원보상법(Commonwealth Employee Compensation Act 1949) 대체 1991 보훈법(개정) 경과에 관한 법률 :(Veterans' Entitlements (Rewrite) Transition Act 1991) 1992 참전용사 귀환 담당기관 (이전)에 관한 법(Repatriation Institutions (Transfer)Act 1992) 1994 군인보상법 제정(Military Compensation Act 1994) 188) 전투복무자를 제외한... -
건강 관련 정보원으로서의 미주 한인 온라인 커뮤니티에 대한 미주 한인들의 인식 및 이용에 대한 연구
김정남, 허지수 한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 49 Pages
한국헬스커뮤니케이션학회 헬스커뮤니케이션연구 2012, Vol.6 No.1 2 43-91 (49 pages)
the parenting section of the website. A few minutes later, they find many replies with some helpful information from the online community participants, including home treatments, names of safe and effective fever-reducing drugs for infants, easy-to-follow instructions for using the drugs, and even information on where the drugs could be purchased. This anecdote well describes rather common... 본 연구는 건강 관련 정보를 필요로 하는 미주 한인들에게 정보원으로서 미주 한인 온라인 커 뮤니티가 어떤 역할을 하고 있는지 알아보고자 하였다. 연구의 이론적 기반으로는 미디어 이용과 의존 모델을 채택하였고, 당뇨병 관련되는 정보추구에 조사의 포커스를 두었다. 당뇨 관련 정보 원으로서, 전통적인 건강/의료 관련 정보원들(e.g., 의사)과 온라인 커뮤니티가 어떻게 이용되고 평가되는지 알아보고자 다른 문화적 동화(acculturation) 수준을 가진 미주 한인들을 대상으로 온라인서베이를 실시하였다. 연구결과, 미주...


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