자료유형
발행기관
- 대한신경정신의학회(31)
- 대한수의학회(15)
- 한국식물병리학회(13)
- 물리치료재활과학회(12)
- 한국습지학회(12)
- 대한생리학회-대한약리학회(11)
- 한국기초간호학회(10)
- 한국노인간호학회(6)
- 대한생리학회(4)
- 환태평양유아교육연구학회(4)
- 대한약리학회(3)
- 인문사회과학기술융합학회(3)
- 대한신경계작업치료학회(2)
- 한국보건기초의학회(2)
- 한국음악교육학회(2)
- 한국탄소학회(2)
- 대한치과교정학회(1)
- 이화여자대학교 교과교육연구소(1)
- 한국가족치료학회(1)
- 한국간호과학회(1)
- 한국기업교육학회(1)
- 한국복지행정학회(1)
- 한국수자원학회(1)
- 한국음악치료학회(1)
- 한국의학교육학회(1)
- 한국특수교육교과교육학회(1)
간행물
- 신경정신의학(31)
- JOURNAL OF VETERINARY SCIENCE(13)
- THE PLANT PATHOLOGY JOURNAL (13)
- PHYSICAL THERAPY REHABILITATION SCIENCE(12)
- 한국습지학회지(12)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(11)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(10)
- 노인간호학회지(6)
- ASIA-PACIFIC JOURNAL OF RESEARCH IN EARLY CHILDHOOD EDUCATION(4)
- 대한생리학회지(4)
- 대한약리학잡지(3)
- 예술인문사회융합멀티미디어논문지(3)
- CARBON LETTERS(2)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(2)
- 음악교육연구(2)
- 재활치료과학(2)
- 한국보건기초의학회지(2)
- KOREAN JOURNAL OF MEDICAL EDUCATION(1)
- THE KOREAN JOURNAL OF ORTHODONTICS(1)
- 가족과 가족치료(1)
- 교과교육학연구(1)
- 기업교육과 인재연구(1)
- 대한간호학회지= JOURNAL OF KOREAN ACADEMY OF NURSING(1)
- 복지행정논총(1)
- 특수교육교과교육연구(1)
- 한국수자원학회논문집(1)
- 한국음악치료학회지(1)
-
Reliability and validity of the patellofemoral disability index as a measure of functional performance and subjective pain in subjects with patellofemoral pain syndrome
Mastour Saeed Alshaharani, Everett Bernell Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Noha S. Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 3 61-66 (6 pages)
(ODI) at baseline after two weeks, and after four weeks. Pearson correlation coefficient was used to assess the criterion validity. Cronbach’s α was used to examine the internal consistency. Intraclass correlation coefficients with 95% confidence interval were computed to examine test-retest reliability. Results: Subjects’ responses within both the PDI and the ODI yielded Pearson correlation coefficient values that were positive and highly significant (range, 0.73-0.97; p<0.001). There was a... -
Predictive analyses for balance and gait based on trunk performance using clinical scales in persons with stroke
Young-keun Woo 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 1호 6 29-34 (6 pages)
of >45 for regression equation for predicting BBS score using TIS score, the coefficient of determination (R2) was 0.234, and the R2 was 0.500 in the group with a BBS score of ≤45. In the group with an FGA score >15 for regression equation for predicting FGA score using TIS score, the R2 was 0.193, and regression equation for predicting FGA score using TIS score, the R2 was 0.181 in the group of FGA score ≤15. In the group of FGA score >15 for regression equation for predicting FGA score using... -
The effect of single trial transcutaneous electrical nerve stimulation on balance and gait function in elderly people with dementia
Ju Yeon Jung, Jin-Hwa Jung, Suk-Chan Hahm, Kyoung-sim Jung, Sung-Jin Kim, Hye Rim Suh, Hwi-young Cho 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 2 59-64 (6 pages)
Objective: Elderly people with dementia experience not only cognitive dysfunction but also motor function deficits, such as balance and gait impairments. Recently, transcutaneous electrical nerve stimulation (TENS) has been used to reduce pain as well as to control muscle spasm, spasticity and motor performance in various types of subjects. The purpose of this study determined the effect of a single trial TENS on balance and gait function in elderly people with dementia. Design: A randomized... -
Immediate effect of self-myofascial release on hamstring flexibility
Ji-hye Jung, Won-jae Choi, Yong-hyuk Lee, Ji-woo Kim, Hyun-ju Kim, Kyoung-ho Lee, Jae-woo Lee, Seung-won Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 8 45-51 (7 pages)
Objective: This study aimed to identify the area with greatest effect using self-myofascial release technique (self-MFR) in the hamstring, suboccipital, and plantar regions. Design: Cross-sectional study. Methods: Twenty-two adult subjects were evaluated for flexibility and hamstring pain threshold after self-MFR. Based on the superficial back line, the self-MFR application areas were the suboccipital region, hamstring, and plantar regions. Self-MFR was applied to each area using a wooden pole... -
Relationship between the quality of life of the caregiver and motor function of children with cerebral palsy
Chang-Kyo Yun 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 5 26-32 (7 pages)
Objective: The purpose of this study was to evaluate the relationship between quality of life (QoL) of the caregiver and disease severity with motor function in children with cerebral palsy (CP). Design: Cross-sectional study. Methods: Research data were collected in the Rehabilitation Clinic of Daegu University. The Gross Motor Function Measure (GMFM-88) and the functional independence measure (FIM) were used for assessment by three occupational therapists, and the 36-item short form health... -
The effect of hip joint exercise using an elastic band on dynamic balance, agility and flexibility in healthy subjects
Dong Hyun Kang, Woo Hyung Lee, Song Lim, Yu Yeong Kim, Soung Wook An, Chang Gyeong Kwon, Gyeong Hee Lee, Nu Ri Choi, Na Yeong Lee, Bo Min 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 6 198-204 (7 pages)
Objective: The purpose of this study was to examine the effects of hip joint exercise using an elastic band on dynamic balance, agility, and flexibility in healthy subjects. Design: Randomized controlled trial. Methods: Thirty-five subjects (between 19 and 23 years) were randomly allocated to two groups: hip flexion exercise (HFE)group (n=17) and the hip abduction exercise (HAE) group (n=18). The HFE group participated in flexion exercise of the hip joint using an elastic band for 50 minutes a... -
Effects of sit-to-stand imagery group training on balance performance in individuals with chronic hemiparetic stroke
Jeong-won Lee, Su-jin Hwang, Sin-ae Ahn 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 2 63-69 (7 pages)
Objective: To evaluate the effects of sit-to-stand (STS) imagery group training (IGT) on STS movement and balance performance for chronic hemiparetic stroke. Design: Randomized controlled trial. Methods: A total of 30 people with chronic hemiparetic stroke (15 for STS-IGT group and 15 for control) were recruited in this study. The STS-IGT group participated in a videotape-based STS-IGT for 30 minutes a day, five days a week for six weeks, while the control group watched a documentary on... -
The comparison of muscle activity according to various conditions during smartphone use in healthy adults
You Lim Kim, Jae-hyun Yoo, Sin-woo Kang, Tae-rim Kim, Nam-yeol Kim, So-jeong Hong, Won-jeong Hwang, Suk Min Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 1호 3 15-21 (7 pages)
Objective: The purpose of this study was to see the changes in muscle activity of the upper limb in persons using a smartphone. Design: Cross-sectional study. Methods: An experiment was conducted to target 15 right-handed university students. Experiments were carried out for students using cell phones for more than a year. In this study, experiments were carried out with one-handed and both handed operation of smartphone use in a sitting position, the same parameters with smartphone use in a... -
Predictive validity of the gait scale in the Performance Oriented Mobility Assessment for stroke survivors
Seung-heon An, Young-ju Jee, Dong-geon Lee, Sun-hae Song, Gyu-chang Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 1호 1 1-8 (8 pages)
Objective: The present study was to investigate the discrimination capacity of the Performance Oriented Mobility Assessment-Gait Scale (POMA-GS), for predicting falls in stroke survivors. Design: Retrospective cohort study. Methods: Data including the characteristics and number of falls of 52 chronic stroke patients from a rehabilitation center were collected. The number of falls each subject had experienced in the previous year were investigated through interviews. The subjects were divided... -
The immediate effects of patellar taping on balance and gait ability in individuals with chronic stroke
Jin Shin, Mee-Hyang Mun, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 9 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 8 125-133 (9 pages)
Objective: The aim of this study is to investigate the effect of patellar taping on balance and gait abilities in chronic stroke patients. Design: Randomized placebo-controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited from R hospital. These study subjects were randomized to the experimental group (n=15) or placebo group (n=15). In the experimental group, patellar taping was applied while for the placebo group, placebo... -
Wheelchair martial arts practitioners have similar bone strength, sitting balance and self-esteem to healthy individuals
Shirley S. M. Fong, Shamay S. M. Ng, Anthony O. T. Li, X. Guo 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 5 27-32 (6 pages)
Objective: The aim of this study was to compare the radial bone strength, sitting balance ability and global self-esteem of wheelchair martial arts practitioners and healthy control participants. Design: Cross-sectional study. Methods: Nine wheelchair martial art practitioners with physical disabilities and 28 able-bodied healthy individuals participated in the study. The bone strength of the distal radius was assessed using the Sunlight Mini-Omni Ultrasound Bone Sonometer; sitting balance was... -
Relationship of neck disability index, shoulder pain and disability index, and visual analogue scale in individuals with chronic neck pain
Su-jin Hwang, Mee-Hyang Mun 물리치료재활과학회 Physical Therapy Rehabilitation Science 4 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 9 111-114 (4 pages)
Objective: Several muscles surrounding neck are vital not only for neck motion, but for upper extremities motions as well. Neck pain would affect neck and shoulder disability. The Neck Disability Index (NDI), Shoulder Pain and Disability Index (SPADI), and Visual Analogue Scale (VAS) are increasingly used to evaluate treatment effectiveness after chronic neck pain. The purpose of this study was to analyze the correlation of neck pain, shoulder pain, and quality of life in patients with chronic... -
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Yiming Shen, Seong Kyu Han, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 2 483-491 (9 pages)
< 0.05). The PVNRVLM neurons showed smaller resting membrane potential, slower rise and decay times, and greater duration of spontaneous action potentials (p < 0.05). The PVNRVLM neurons received greater inhibitory synaptic inputs (frequency, p < 0.05) with a shorter rise time (p < 0.05). Taken together, the results indicate that the two pre-sympathetic neurons differ in their intrinsic and extrinsic electrophysiological properties, which may explain the lower firing activity of the PVNRVLM... -
Alginate encapsulation preserves the quality and fertilizing ability of Mediterranean Italian water buffalo (Bubalus bubalis) and Holstein Friesian (Bos taurus) spermatozoa after cryopreservation
Sara Perteghella, Alessandro Gaviraghi, Silvia Cenadelli, Valeria Bornaghi, Andrea Galli, Barbara Crivelli, Barbara Vigani, Dani 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 11 81-88 (8 pages)
semen, low resistance of sperm cells in the female tract, difficulties in estrus detection, and variable estrus duration. Although AI procedures are commonly used in bovine, use of AI has been limited in buffalo. In the zootechnical field, different studies have been conducted to develop techniques for improvement of fertilizing ability of buffalo spermatozoa after AI. In this study, for the first time, the use of alginate encapsulation and cryopreservation of buffalo spermatozoa is described,... -
Quantitative CT assessment of bone mineral density in dogs with hyperadrenocorticism
Donghoon Lee, Youngjae Lee, Wooshin Choi, Jinhwa Chang, Ji-Houn Kang, Ki-Jeong Na, Dong-Woo Chang 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 18 531-542 (12 pages)
Canine hyperadrenocorticism (HAC) is one of the most common causes of general osteopenia. In this study, quantitative computed tomography (QCT) was used to compare the bone mineral densities (BMD) between 39 normal dogs and 8 dogs with HAC (6 pituitary-dependent hyperadrenocorticism [PDH]; pituitary dependent hyperadrenocorticism, 2 adrenal hyperadrenocorticism [ADH]; adrenal dependent hyperadrenocorticism) diagnosed through hormonal assay. A computed tomogaraphy scan of the 12th thoracic to 7th... -
Tissue Doppler and strain imaging of left ventricle in Beagle dogs with iatrogenic hypercortisolism
Heejin Oui, Sunghoon Jeon, Gahyun Lee, Seungjo Park, Kyoung-Oh Cho, Jihye Choi 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 14 357-365 (9 pages)
Changes in radial and longitudinal left ventricular (LV) function were investigated in beagles with iatrogenic hypercortisolism. A total of 11 normal dogs were used, and 2 mg/kg prednisone was administered per oral q12 h for 28 days to 7 out of 11 dogs to induce iatrogenic hypercortisolism. Body weight, blood pressure, conventional echocardiography and tissue Doppler imaging (TDI) of normal and iatrogenic hypercortisolism groups were conducted. The myocardial wall velocity of the LV was measured... -
Association of the time that elapsed from last vaccination with protective effectiveness against foot-and-mouth disease in small ruminants
Ehud Elnekave, Boris Even-Tov, Boris Gelman, Beni Sharir, Eyal Klement 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 11 87-92 (6 pages)
the average time that elapsed since last vaccination and the disease incidence (n = 5; Spearman correlation coefficient: rs = 1.0, p< 0.01). In addition, non-vaccinated lambs fed colostrum from dams vaccinated more than 2 months before parturition had a mortality rate of 33%. Administration of emergency vaccination 2 days after the occurrence of the index case was the probable reason for the rapid blocking of the FMD spread within 6 days from its onset in the pen. -
Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry
Joon-Hyeok Jeon, Hae-Won Jung, Hyo-Mi Jang, Jong-Hyun Moon, Ki-Tae Park, Hee-Chun Lee, Ha-Young Lim, Jung-Hyang Sur, By 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 10 75-85 (11 pages)
(IL)-6 with clinical prognosis was assessed. Ischemic stroke was induced by permanent middle cerebral artery occlusion (MCAO) in nine healthy experimental dogs. The dogs were divided into three groups according to survival time and duration of the experimental period: group A (survived only 1 day), group B (1-week experimental period), and group C (2-week experimental period). Neurologic status was evaluated daily. Magnetic resonance imaging (MRI) was performe... -
Assessing PCV2 antibodies in field pigs vaccinated with different porcine circovirus 2 vaccines using two commercial ELISA systems
Min-Kyoung Shin, Seung Hyun Yoon, Myung Hwui Kim, Young Soo Lyoo, Seung Won Suh, Han Sang Yoo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 4 25-29 (5 pages)
and 42 negative samples, indicating 78.7% agreement. In addition, the Pearson coefficient (0.636) indicated a moderate correlation between data from the two ELISAs. Results from the farms with pigs vaccinated with the three different PCV2 vaccines demonstrated that most of the vaccinated animals underwent seroconversion. However, the increase and duration of antibody titers varied depending on the vaccine, the presence of maternal antibodies, and the vaccination... -
C-reactive protein as an indicator of inflammatory responses to experimentally induced cystitis in dogs
Kyoung-won Seo, Jong-bok Lee, Jin-Ok Ahn, Hee-woo Lee, Cheol-yong Hwang, Hwa-young Youn*, Chang-woo Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 9 179-185 (7 pages)
The aim of this study was to demonstrate and assess C-reactive protein (CRP) changes in dogs with induced bacterial cystitis with or without antibiotics. We also evaluated availability of CRP levels to serve as an indicator for monitoring or diagnosing bacterial cystitis. Serial CRP concentrations in dogs with induced bacterial cystitis were higher than those of controls (p < 0.001). CRP concentrations peaked on day 7 and gradually decreased thereafter. In the treatment group, CRP... -
Autoantibodies against thyroid hormones and their influence on thyroxine determination with chemiluminescence immunoassay in dogs
Marion Piechotta*, Michael Arndt, Hans-Otto Hoppen 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 3 191-196 (6 pages)
= 110). The incidence of T4AA and T3AA, determined using radiometric assay, was low (0.5% and 3.8%) and higher in hypothyroid dogs compared to dogs suspicious for hypothyroidism (Group 2-4) (p<0.05). T4AA was not detected in dogs with normal T4 and elevated TSH. T4 concentrations of T4AA positive samples determined using HPLC were comparable to results obtained by chemiluminescence immunoassay. These findings indicate that the probability of interference of T4AA leading to falsely elevated T4... -
Disposition kinetics and dosage regimen of levofloxacin on concomitant administration with paracetamol in crossbred calves
Vinod K. Dumka* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 7 357-360 (4 pages)
declined to 6.39±0.16 ■g/ml at 10 min. The drug level above the MIC90 in plasma, was detected for up to 10 h. Levofloxacin was rapidly distributed from blood to the tissue compartment as evidenced by the high values of the distribution coefficient, ■ (17.3 ± 1.65 /h) and the ratio of K12/K21 (1.83 ± 0.12). The values of AUC and Vdarea were 12.7±0.12 ■g.h/ml and 0.63 ± 0.01 l/kg. The high ratio of the AUC/ MIC (126.9±1.18) obtained in this study indicated the... -
Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves
Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 4 21-25 (5 pages)
the high distribution coefficient values (8.67 ± 0.46/h), and by the drug’s rate of transfer constant from the central to the peripheral compartment, K12 (4.94 ± 0.31/h). The elimination halflife and the volume of distribution were 2.14 ± 0.02 h and 0.42 ± 0.005 l/kg, respectively. Once the distribution equilibrium was reached between the tissues and plasma, the total body clearance (ClB) and the ratio of the drug present in the peripheral to the central compartment (T/P ratio) were 0.14 ±... -
Surgical treatment of spinal cord compression in client owned dogs with different grades of neurological dysfunction
Maria Kuricova , Valent Ledecky , Tomas Liptak 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 2호 9 113-116 (4 pages)
-
Comparative pharmacokinetics of norfloxacin-glycine acetate after single oral administration and medication with drinking water in broilers
JongHwanLim, ByoungYongLim, ByungKwonPark, MyongSeokKim, BeomSuJang, SeungChunPark, HyoInYun 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2004, 제 44권 제 2호 7 201-206 (6 pages)
-
두부방사선 분석에 의한 상악전치부 후방이동시 연조직 변화 예측에 대한 연구
최진희(Jin-Hee Choi), 이진우(Jin-Woo Lee), 차경석(Kyung-Suk Cha) 대한치과교정학회 The Korean Journal of Orthodontics 14 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 1호 6 65-78 (14 pages)
본 연구는 성장에 의한 효과를 배제한 교정치료시의 연조직 변화와 치아 및 악골의 수평적, 수직적 움직임과의 상관관계를 알아보고 예측 가능성을 검토하기 위해 Angle씨 2급 1류 부정교합 환자 41명을 대상으로 치아 및 악골, 연조직의 수평, 수직이동의 평균 변화량을 측정하고 연조직에 대한 계단식 다중 회귀분석을 시행하였으며 다음과 같은 결론을 얻었다 1. 경조직 계측항목 중 상악 중절치의 수평이동 및 기울기, 하악 중절치의 수평 및 수직이동, 수평피개량, 수직피개량, interincisal angle, 하악골 위치 변화, A, B 경조직... -
Korean Music Performance Anxiety Scale: Validation and Reliability
Su-Young Bae 한국음악교육학회 음악교육연구 21 Pages
한국음악교육학회 음악교육연구 2020, 제 49권 제 3호 2 29-49 (21 pages)
The purpose of the present study was to develop a Korean Music Performance Anxiety Scale (K-MPAS) to measure music performance anxiety of college music major students in Korea. Items were developed based on previous scales: the Music Performance Anxiety Inventory for Adolescents (MPAI-A) by Osborne & Kenny (2005) and the Personal Report of Confidence as a Speaker (PRCS) by Paul (1966). The preliminary K-MPAS comprising 26 items was conducted to 230 college music major students to verify the... -
Comparison of electrophysiological effects of calcium channel blockers on cardiac repolarization
Hyang-AeLee, Sung-AeHyun, Sung-GurlPark, Ki-SukKim, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 15 119-127 (9 pages)
of action potential duration (APD) due to the reduction of Ca2+ channel current (ICa) might increase the risk of arrhythmia. In this study we investigated the electrophysiologicaleffects of nicardipine (NIC), isradipine (ISR), and amlodipine (AML) on the cardiac APD in rabbit Purkinje fibers, voltage-gated K+ channel currents (IKr, IKs) and voltage-gated Na+ channel current (INa). The concentration-dependent inhibition of Ca2+ channel currents (ICa) was examined in rat cardiomyocytes; these CCBs... -
Blockade of Kv1.5 by paroxetine, an antidepressant drug
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 10 75-82 (8 pages)
and a Hill coefficient of 4.11 µM and 0.98, respectively. Paroxetine accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between –30 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to 0 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance d of 0.32. The binding (k+1) and unbinding (k–1) rate...


전체 선택해제

총


