자료유형
발행기관
- 대한생리학회-대한약리학회(12)
- 대한신경정신의학회(7)
- 대한약학회(4)
- 대한통증학회(3)
- 한국약제학회(3)
- 대한수의학회(2)
- 대한안면통증구강내과학회(2)
- 대한구강생물학회(1)
- 대한신경외과학회(1)
- 대한족부족관절학회(1)
- 대한치과마취과학회(1)
- 대한치과이식임플란트학회(1)
- 영남의대학술지편집위원회(1)
- 한국광과학회(1)
- 한국보건기초의학회(1)
- 한국응용약물학회(1)
- 한국임상약학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(12)
- 신경정신의학(7)
- 대한통증학회지(3)
- 약제학회지(3)
- ARCHIVES OF PHARMACAL RESEARCH : A PUBLICATION OF THE PHARMACEUTICAL SOCIETY OF KOREA(2)
- JOURNAL OF VETERINARY SCIENCE(2)
- 약학회지(2)
- BIOMOLECULES & THERAPEUTICS(1)
- INTERNATIONAL JOURNAL OF ORAL BIOLOGY : OFFICIAL JOURNAL OF THE KOREAN ACADEMY OF ORAL BIOLOGY AND T(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- JOURNAL OF KOREAN NEUROSURGICAL SOCIETY(1)
- JOURNAL OF ORAL MEDICINE AND PAIN(1)
- JOURNAL OF PHOTOSCIENCE: AN INTERNATIONAL JOURNAL OFFICAIL ORGAN OF THE KOREAN SOCIETY OF PHOTOSCIEN(1)
- 대한구강내과학회지(1)
- 대한족부족관절학회지(1)
- 대한치과마취과학회지(1)
- 영남의대 학술지(1)
- 한국보건기초의학회지(1)
- 한국임상약학회지(1)
전체 선택해제
총 43건 검색
본문검색 결과만 보기
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The efficacy of combination treatment of gabapentin and electro-acupuncture on paclitaxel-induced neuropathic pain
MinJoonKim, JiHwanLee, JoUngJang, FuShiQuan, SunKwangKim, WoojinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 11 657-666 (10 pages)
a chemotherapeutic drug, induces severe peripheral neuropathy. Gabapentin (GBT) is a first line agent used to treat neuropathic pain, and its effect is mediated by spinal noradrenergic and muscarinic cholinergic receptors. Electro-acupuncture (EA) is used for treating various types of pain via its action through spinal opioidergic and noradrenergic receptors. Here, we investigated whether combined treatment of these two agents could exert a synergistic effect on paclitaxel-induced cold and... -
Identification of Differentially Expressed Genes by Gabapentin in Cultured Dorsal Root Ganglion in a Rat Neuropathic Pain Model
Heo. Ji Hye, Lee. Seung Ha, Chang. Kyung Ha, Han. Eun Hye, Lee. Seung Gwan, Choi. Dal Woong, Kim. Suhng Wook 한국응용약물학회 Biomolecules & therapeutics 6 Pages
한국응용약물학회 Biomolecules & therapeutics 2013, Vol.21 No.2 126-131 (6 pages)
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Investigation on the Interaction of Gabapentin with Bovine Serum Albumin by Spectroscopic Techniques
Ashoka. S., Seetharamappa. J., Kandagal. P.B., Shaikh. S.M.T. 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 5 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 2005, Vol.12 No.3 113-117 (5 pages)
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외상성 신경병증성 통증의 각 임상증상에 대한 Gabapentin의 효과
김영기, 조윤우, Kim. Yeung-Ki, Cho. Yun-Woo 영남의대학술지편집위원회 영남의대 학술지 9 Pages
영남의대학술지편집위원회 영남의대 학술지 2004, Vol.21 No.1 82-90 (9 pages)
외상성 신경손상으로 인한 신경병증성 통증을 호소하는 환자에게 gabapentin을 투여하였을 때 신경병증성 통증의 각 증상 모두 유의하게 감소하였다. 신경병증성 통증의 각 증상 중 발작성 자발통이 열성 유발통보다 더욱 유의하게 감소하였다. -
신경병증성 통증환자에서 Gabapentin 단일 요법의 효과 -증례 보고-
김우선, 한영진, 최훈, Kim. Woo-Sun, Han. Young-Jin, Choe. Huhn 대한통증학회 大韓痛症學會誌 4 Pages
대한통증학회 大韓痛症學會誌 2000, Vol.13 No.1 101-104 (4 pages)
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신경병증성 통증 환자에서 Gabapentin 사용의 임상경험 -증례 보고-
임경준, 정용훈, 조남수, Lim. Kyung-Joon, Chung. Yong-Hun, Cho. Nam-Su 대한통증학회 大韓痛症學會誌 4 Pages
대한통증학회 大韓痛症學會誌 1999, Vol.12 No.2 242-245 (4 pages)
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대상포진후 신경통에서 Gabapentin의 효과
이두익, 김동옥, 김건식, 권무일, 신광일, 강화자, Lee. Doo-Ik, Kim. Dong-Ok, Kim. Keon-Sik, Kwon. Moo-Il, Shin. Kwang-Il, Kang. Wha-Ja 대한통증학회 大韓痛症學會誌 3 Pages
대한통증학회 大韓痛症學會誌 1999, Vol.12 No.2 188-190 (3 pages)
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백서에서 Gabapentin 전신투여가 Facial Formalin Test에 미치는 영향
김철홍, 백승완, 김해규, 권재영, 김경훈, 최성환, Kim. Chul-Hong, Baik. Seong-Wan, Kim. Hae-Kyu, Kwon. Jae-Young, Kim. Kyoung-Hun, Choi. Sung-Hwan 대한치과마취과학회 대한치과마취과학회지 6 Pages
대한치과마취과학회 대한치과마취과학회지 2003, Vol.3 No.2 92-97 (6 pages)
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In Vitro/in Vivo Relationship of Gabapentin from a Sustained-Release Tablet Formulation: A Pharmacokinetic Study in The Beagle Dog
Rhee. Yun-Seok, Park. Seok, Lee. Tae-Won, Park. Chun-Woong, Nam. Tae-Young, Oh. Tack-Oon, Jeon. Ji-Woong, Han. Sang-Beom, Lee. Dong-Soo, 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 7 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2008, Vol.31 No.7 911-917 (7 pages)
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The Effect of MDR1 G2677T/A Polymorphism on Pharmacokinetics of Gabapentin in Healthy Korean Subjects
Kang. Hyun-Ah, Cho. Hea-Young, Lee. Yong-Bok 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.1 96-101 (6 pages)
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The Effects of Gabapentin in Treatment of Burning Mouth Syndrome: Retrospective Pilot Study
Heo. Jun-Young, Ok. Soo-Min, Jeong. Sung-Hee, Kim. Kyung-Hee, Ahn. Yong-Woo 대한안면통증구강내과학회 Journal of Oral Medicine and Pain 4 Pages
대한안면통증구강내과학회 Journal of Oral Medicine and Pain 2014, Vol.39 No.3 96-99 (4 pages)
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Glia Dose not Participate in Antinociceptive Effects of Gabapentin in Rats with Trigeminal Neuropathic Pain
Yang. Kui-Y., Kim. Hak-K., Jin. Myoung-U., Ju. Jin-S., Ahn. Dong-K. 대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 9 Pages
대한구강생물학회 International journal of oral biology : official journal of the Korean Academy of Oral Biology and t 2012, Vol.37 No.3 121-129 (9 pages)
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Inoculation of Lewis lung carcinoma cells enhances formalin-induced pain behavior and spinal Fos expression in mice
Jae-Gyun Choi, Jae-Min Kim, Dong-Wook Kang, Jung-Wan Choi, Jin Bong Park, Seong-Hun Ahn, Yeonhee Ryu, Hyun-Woo Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 2 267-272 (6 pages)
The incidence of lung cancer has rapidly increased and cancer patients at a later cancer stage frequently suffer from unbearable cancer-associated pain. However, the pathophysiology of lung cancer pain has not been fully described due to a lack of appropriate animal models. This study was designed to determine the effect of Lewis lung carcinoma (LLC) cell inoculation on formalin-induced pain behavior and spinal Fos expression in C57BL/6 mice. LLC cells (1.5 × 10, 2.5 × 10, 3.0 × 10 or 5.0 ×... -
Syringomyelia in three small breed dogs secondary to Chiari-like malformation: clinical and diagnostic findings
Chul Park, Byeong-Teck Kang, Jong-Hyun Yoo, Hee-Myung Park* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 16 365-367 (3 pages)
Three small breed dogs were referred for the evaluation of neurologic deficits. Upon physical and neurologic examination, all dogs displayed hyperesthesia, pain, and neck stiffness. Magnetic resonance imaging was performed on the brain and spinal cord, and all three dogs presented Chiari- like malformations and syringomyelia. These dogs were treated with prednisolone and furosemide, and showed rapid improvement of clinical signs. Chiari malformations and syringomyelia were not improved because... -
Effects of tianeptine on symptoms of fibromyalgia via BDNF signaling in a fibromyalgia animal model
HwayoungLee, JiyunIm, HansolWon, WooyoungNam, YoungOckKim, SangWonLee, SanghyunLee, Ik-HyunCho, Hyung-KiKim, Jun-TackKwon, Hak-JaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 1 361-370 (10 pages)
Previous reports have suggested that physical and psychological stresses may trigger fibromyalgia (FM). Stress is an important risk factor in the development of depression and memory impairments. Antidepressants have been used to prevent stress-induced abnormal pain sensation. Among various antidepressants, tianeptine has been reported to be able to prevent neurodegeneration due to chronic stress and reverse decreases in hippocampal volume. To assess the possible effect of tianeptine on FM... -
Association study between OCTN1 functional haplotypes and Crohn’s disease in a Korean population
EunSukJung, HyoJinPark, KyoungAeKong, JiHaChoi, JaeHeeCheon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 2 11-17 (7 pages)
Crohn’s disease (CD) is a chronic inflammatory bowel disease with multifactorial causes including environmental and genetic factors. Several studies have demonstrated that the organic cation/carnitine transporter 1 (OCTN1) nonsynonymous variant L503F is associated with susceptibility to CD. However, it was reported that L503F is absent in Asian populations. Previously, we identified and functionally characterized genetic variants of the OCTN1 promoter region in Koreans.In that study, four... -
Involvement of spinal muscarinic and serotonergic receptors in the anti-allodynic effect of electroacupuncture in rats with oxaliplatin-induced neuropathic pain
JiHwanLee, DonghyunGo, WoojinKim, GiseogLee, HyojeongBae, FuShiQuan, SunKwangKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.4 10 407-414 (8 pages)
This study was performed to investigate whether the spinal cho-linergic and serotonergic analgesic systems mediate the relieving effect of elec-troacupuncture (EA) on oxaliplatin-induced neuropathic cold allodynia in rats. The cold allodynia induced by an oxaliplatin injection (6 mg/kg, i.p.) was evaluated by immersing the rat’s tail into cold water (4oC) and measuring the withdrawal latency. EA stimulation (2 Hz, 0.3-ms pulse duration, 0.2~0.3 mA) at the acupoint ST36, GV3, or LI11 all showed... -
Identification and Functional Characterization of Novel Genetic Variations in the OCTN1 Promoter
HyoJinPark, JiHaChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 12 169-175 (7 pages)
Human organic cation/carnitine transporter 1 (OCTN1) plays an important role in the transport of drugs and endogenous substances. It is known that a missense variant of OCTN1 is significantly associated with Crohn’s disease susceptibility. This study was performed to identify genetic variants of the OCTN1 promoter in Korean individuals and to determine their functional effects. First, the promoter region of OCTN1 was directly sequenced using genomic DNA samples from 48 healthy Koreans. OCTN1... -
Modern Methods for Analysis of Antiepileptic Drugs in the Biological Fluids for Pharmacokinetics, Bioequivalence and Therapeutic Drug Monitoring
JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 1 67-82 (16 pages)
Epilepsy is a chronic disease occurring in approximately 1.0% of the world's population. About 30% of the epileptic patients treated with availably antiepileptic drugs (AEDs) continue to have seizures and are considered therapy-resistant or refractory patients. The ultimate goal for the use of AEDs is complete cessation of seizures without side effects. Because of a narrow therapeutic index of AEDs, a complete understanding of its clinical pharmacokinetics is essential for understanding of the... -
Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats
JiSeonSon, YoungBaeKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 2 359-364 (6 pages)
the manifestation of allodynia. The BD 1047 (10, 30, 100 mg/kg) administered on postoperative days 0∼5 dose-dependently suppressed both the induction of allodynia and the elevation of the spinal pERK expression in a manner comparable with that of gabapentin (100 mg/kg). At 7 days post-CCD surgery, BD1047 (10, 30, 100 mg/kg) administration also produced anti-nociceptive effects on the mechanical and cold allodynia similar with those of gabapentin (100 mg/kg). Therefore, this data suggested that... -
The Effects of Tramadol on Electroencephalographic Spectral Parameters and Analgesia in Rats
Hwan-SooJang, Il-SungJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 12 191-198 (8 pages)
The effects of different doses of tramadol on analgesia and electroencephalographic (EEG) spectral parameters were compared in rats. Saline or tramadol 5, 10, 20 or 40 mg/kg was administered. The degree of analgesia was evaluated by tail-flick latency, and the degree of seizure was measured using numerical seizure score (NSS). Additionally, band powers, median power frequency and spectral edge frequency 95 were measured to quantify the EEG response. All doses of tramadol produced spike-wave... -
Loss of hsp70.1 Decreases Functional Motor Recovery after Spinal Cord Injury in Mice
HyunJeongKim, Ji-InJung, YoungkyungKim, Jae-SeonLee, YoungWookYoon, JunesunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 7 157-161 (5 pages)
Heat shock proteins (HSPs) are specifically induced by various forms of stress. Hsp70.1, a member of the hsp70 family is known to play an important role in cytoprotection from stressful insults. However, the functional role of Hsp70 in motor function after spinal cord injury (SCI) is still unclear. To study the role of hsp70.1 in motor recovery following SCI, we assessed locomotor function in hsp70.1 knockout (KO) mice and their wild-type (WT) mice via the Basso, Beattie and Bresnahan (BBB)... -
Are Spinal GABAergic Elements Related to the Manifestation of Neuropathic Pain in Rat?
JaeheeLee, SeungKeunBack, EunJeongLim, GyuChongCho, MyungAhKim, HeeJinKim, MinHeeLee, HeungSikNa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 1 59-69 (11 pages)
Impairment in spinal inhibition caused by quantitative alteration of GABAergic elements following peripheral nerve injury has been postulated to mediate neuropathic pain. In the present study, we tested whether neuropathic pain could be induced or reversed by pharmacologically modulating spinal GABAergic activity, and whether quantitative alteration of spinal GABAergic elements after peripheral nerve injury was related to the impairment of GABAergic inhibition or neuropathic pain. To these aims,... -
Mechanical Hyperalgesia Induced by Blocking Calcium-activated Potassium Channels on Capsaicin-sensitive Afferent Fiber
KyungHeeLee, HongKeeShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.5 8 215-219 (5 pages)
Small and large conductance Ca2+-activated K+ (SKCa and BKCa) channels are implicated in the modulation of neuronal excitability. We investigated how changes in peripheral KCa channel activity affect mechanical sensitivity as well as the afferent fiber type responsible for KCa channel-induced mechanical sensitivity. Blockade of SKCa and BKCa channels induced a sustained decrease of mechanical threshold which was significantly attenuated by topical application of capsaicin onto afferent fiber and... -
Physiological, Pharmacological and Toxicological Implications of Heterodimeric Amino Acid Transporters
YoshikatsuKanaiHitoshiEndou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.3 1 117-128 (12 pages)
The heterodimeric amino acid transporter family is a subfamily of SLC7 solute transporter family which includes 14-transmembrane cationic amino acid transporters and 12-transmembrane heterodimeric amino acid transporters. The members of heterodimeric amino acid transporter family are linked via a disulfide bond to single membrane spanning glycoproteins such as 4F2hc (4F2 heavy chain) and rBAT (related to b0, -amino acid transporter). Six members are associated with 4F2hc and one is linked... -
양극성 장애 급성기 치료에 대한 Lamotrigine과 Lithium의 비교
권영준, 정희연, 박인준 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 5호 13 885-892 (8 pages)
연구목적： 새로운 항경련제인 lamotrigine의 급성기 양극성장애 조증과 우울증에 대한 치료효과를 lithium과 비교 평 가하기 위해 본 연구를 시행하였다. 방 법： 양극성 장애 조증 환자 47명(남자 26명, 여자 21명)과 양극성 장애 우울증 환자 43명(남자 21명, 여자 22명)에게 각각 무작위로 lamotrigine과 lithium, 그리고 위약을 6주간 투여하였고, 조증 환자는 Young s Rating Scale for Mania를, 우울증 환자는 Hamilton Rating Scale for Depression을 사용하여 매주 그 치료 효과를 평가하였다. 결 과： 조증 환자들에 대한... -
암 환자와 가족에 대한 정신의학적·심리사회적 개입
대한신경정신의학회 신경정신의학 2007, 제 46권 제 5호 3 430-446 (17 pages)
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다양한 신체증상을 주소로 내원한 부종양성 근강직증후군 1예
명우재, 강은호, 유범희 대한신경정신의학회 신경정신의학 4 Pages
대한신경정신의학회 신경정신의학 2009, 제 48권 제 5호 13 394-397 (4 pages)
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한국형 범불안장애 약물치료 알고리듬 2009 (III) : 공존질환의 치료
이상혁, 양종철, 서호석, 이준엽, 김민숙, 김찬형, 유범희, 한국형 범불안장애 약물치료 알고리듬 2009 연구단 대한신경정신의학회 신경정신의학 6 Pages
대한신경정신의학회 신경정신의학 2010, 제 49권 제 6호 7 564-569 (6 pages)
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한국형 범불안장애 약물치료 알고리듬 2009 ( II ) : 약물치료 알고리듬 및 장기 약물치료 전략
이준엽, 김민숙, 이상혁, 양종철, 김찬형, 유범희, 서호석, 한국형 범불안장애 약물치료 알고리듬 2009 연구단 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 2010, 제 49권 제 6호 6 553-563 (11 pages)
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임플란트 수술 전후의 통증조절을 위한 합리적인 경구 진통제 선택법
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임플란트 시술은 치과영역에서 흔하게 시행되는 수술 중의 하나 이며 술 후 통증은 환자들의 주요한 불만사항 중의 하나이다. 대부분 의 환자들은 수술 전에 통증에 관련된 질문을 하며, 외과적 시술에 대한 불안과 공포를 보인다. 수술 후 적절하지 못한 통증 조절은 임 플란트 수술 후 출혈 및 부종, 수면장애, 음식물 섭취의 저하 등을 야기할 수 있다1). 건강한 일반인의 경우 정상적인 과정의 임플란트 시술 후 경도에서 중등도의 통증과 염증반응을 겪게 되며, 이 경우 금기사항이 없는 한 비스테로이드성 소염 진통제(NSAIDs)를... -
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