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전체 선택해제
총 954건 검색
본문검색 결과만 보기
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Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)
Tomohiro Kondo, Suguru Yoshida, Hiroaki Nagai, Ai Takeshita, Masaki Mino, Hiroshi Morioka, Takayuki Nakajima, Ken Takeshi Kusakabe, Tosh 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 5 505-511 (7 pages)
In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet d’Ammon 1 (CA1) region of the hippocampus. Neuronal cell death in the hippocampus and changes in behavior were examined after BCCAO was performed for 5 min in the gerbils. One day after BCCAO, the pyramidal neurons of the CA1 region of the hippocampus showed degenerative changes (clumped... -
Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways
YanjiCui, Jee-YunPark, JinjiWu, JiHyungLee, Yoon-SilYang, Moon-SeokKang, Sung-CherlJung, JooMinPark, Eun-SookYoo, Seong-HoKim, SangmeeAhnJ 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 5 219-228 (10 pages)
of NADPH oxidase complex responsible for microglial reactive oxygen species (ROS) generation. Finally, DEK significantly attenuated neuronal cell death that is induced by treatment of microglial conditioned media containing neurotoxic secretary molecules. These neuroprotective effects of DEK were also confirmed in a neuron-microglia co-culture system using enhanced green fluorescent protein (EGFP)-transfected B35 neuroblastoma cell line. Taken together, these results suggest that DEK suppresses... -
GS28 Protects Neuronal Cell Death Induced by Hydrogen Peroxide under Glutathione-Depleted Condition
HwaOkLee, YuJeongByun, Kyung-OkCho, SeongYunKim, Seong-BeomLee, Ho-ShikKim, Oh-JooKwon, Seong-WhanJeong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 5 149-156 (8 pages)
reticulum (ER) and Golgi. Additional role(s) of GS28 within cells have not been well characterized. We observed decreased expression of GS28 in rat ischemic hippocampus. In this study, we examined the role of GS28 and its molecular mechanisms in neuronal (SK-N-SH) cell death induced by hydrogen peroxide (H2O2). GS28 siRNA-transfected cells treated with H2O2 showed a significant increase in cytotoxicity under glutathione (GSH)-depleted conditions after pretreatment with buthionine sulfoximine,... -
Bark Constituents from Mushroom-detoxified Rhus verniciflua Suppress Kainic Acid-induced Neuronal Cell Death in Mouse Hippocampus
Jong-SeonByun, YoonHeeHan, Sung-JunHong, Sung-MiHwang, Yong-SooKwon, HeeJaeLee, Sung-SooKim, Myong-JoKim, WanjooChun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 5 279-283 (5 pages)
a mouse model of kainic acid (KA)-induced excitotoxicity. KA resulted in significant apoptotic neuronal cell death in the CA3 region of mouse hippocampus. However, seven daily administrations of RVH-1 or RVH-2 prior to KA injection significantly attenuated KA-induced pyramidal neuronal cell death in the CA3 region. Furthermore, pretreatment with RVH-1 and RVH-2 also suppressed KA-induced microglial activation in the mouse hippocampus. The present study demonstrates that RVH-1 and RVH-2 isolated... -
Neuroprotective Effect of Visnagin on Kainic Acid-induced Neuronal Cell Death in the Mice Hippocampus
Min-SooKwon, Jin-KooLee, Soo-HyunPark, Yun-BeomSim, Jun-SubJung, Moo-HoWon, Seon-MiKim, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 2 257-263 (7 pages)
contraction by inhibition of calcium influx into blood cells. However, the neuroprotective effect of visnagin was not clearly known until now. Thus, we investigated whether visnagin has a neuroprotective effect against kainic acid (KA)-induced neuronal cell death. In the cresyl violet staining, pre-treatment or post-treatment visnagin (100 mg/kg, p.o. or i.p.) showed a neuroprotective effect on KA (0.1Ռg) toxicity. KA-induced gliosis and proinflammatory marker (IL-1Ղ, TNF-Ձ,... -
Curcumin Attenuates Glial Cell Activation But Cannot Suppress Hippocampal CA3 Neuronal Cell Death in i.c.v. Kanic Acid Injection Model
JaeyoungCho, Pil-JaeKong, WanjooChun, Yeo-OkMoon, Yee-TaePark, So-YoungLim, Sung-SooKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 3 307-310 (4 pages)
in neuronal death of cornu ammonia 1 (CA1), reactive gliosis and biochemical changes in the hippocampus and other limbic structures. Several lines of evidence suggest that reactive oxygen species (ROS) play a pivotal role in the pathogenesis of excitotoxic death by KA. Curcumin has been known to possess anti-oxidative and anti-inflammatory activities. In this study, the effects of curcumin on KA induced hippocampal cell death, reactive gliosis and biochemical changes in reactive glia were... -
Association of the Neuronal Cell Adhesion Molecule (NrCAM) Gene Variants with Personality Traits and Addictive Symptoms in Methamphetamine Use Disorder
ByungKuk Yoo, JooCheol Shim, ByungDae Lee, Choongrak Kim, YoungIn Chung, JeMin Park, SungGon Kim, JiHoon Kim, YoungMin Lee, EunSoo Moon, D 대한신경정신의학회 Psychiatry Investigation 8 Pages
대한신경정신의학회 Psychiatry Investigation 2012, 제 9권 제 4호 14 400-407 (8 pages)
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Differential Protein Quantitation in Mouse Neuronal Cell Lines using Amine-Reactive Isobaric Tagging Reagents with Tandem Mass Spectrometry
Cho. Kun, Park. Gun-Wook, Kim. Jin-Young, Lee. Sang-Kwang, Oh. Han-Bin, Yoo. Jong-Shin 한국질량분석학회 Mass spectrometry letters 4 Pages
한국질량분석학회 Mass spectrometry letters 2010, Vol.1 No.1 25-28 (4 pages)
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Involvement of Intracellular Ca2+-and PI3K-Dependent ERK Activation in TCDD-Induced Inhibition of Cell Proliferation in SK-N-SH Human Neuronal Cells
Yang. Seun-Ah, Lee. Yong-Soo, Jin. Da-Qing, Jung. Jae-Wook, Park. Byung-Chul, Lee. Yoon-Seok, Paek. Seung-Hwan, Jeong. Tae-Cheon, Choi. 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 6 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2005, Vol.13 No.2 78-83 (6 pages)
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Protective Effect of Sanguisorba officinalis L. Root on Amyloid ${eta}$ Protein (25-35)-induced Neuronal Cell Damage in Cultured Rat Cortical Neuron
Ban. Ju-Yeon, Cho. Soon-Ock, Jeon. So-Young, Song. Kyung-Sik, Bae. Ki-Hwan, Seong. Yeon-Hee 한국약용작물학회 韓國藥用作物學會誌 8 Pages
한국약용작물학회 韓國藥用作物學會誌 2005, Vol.13 No.5 219-226 (8 pages)
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Protection of Amyloid ${eta}$ Protein (25-35)-induced Neuronal Cell Damage by Methanol Extract of New Stem of Phyllostachys nigra Munro var. henonis Stapf in Cultured Rat Cortical Neuron
Ban. Ju-Yeon, Cho. Soon-Ock, Kwon. Soon-Ho, Kim. Jin-Bae, Song. Nak-Sul, Bae. Ki-Whan, Song. Kyung-Sik, Seng. Yeon-Hee 한국약용작물학회 韓國藥用作物學會誌 8 Pages
한국약용작물학회 韓國藥用作物學會誌 2005, Vol.13 No.2 95-102 (8 pages)
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Antioxidant and Neuronal Cell Protective Effects of Columbia Arabica Coffee with Different Roasting Conditions
Jeong. Ji Hee, Jeong. Hee Rok, Jo. Yu Na, Kim. Hyun Ju, Lee. Uk, Heo. Ho Jin 한국식품영양과학회 Preventive nutrition and food science 8 Pages
한국식품영양과학회 Preventive nutrition and food science 2013, Vol.18 No.1 30-37 (8 pages)
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Effects of Fucoidan on Neuronal Cell Proliferation: Association with NO Production through the iNOS Pathway
Lee. Hye-Rim, Do. Hang, Lee. Sung-Ryul, Sohn. Eun-Soo, Pyo. Suhk-Neung, Son. Eun-Wha 한국식품영양과학회 Journal of food science and nutrition 5 Pages
한국식품영양과학회 Journal of food science and nutrition 2007, Vol.12 No.2 74-78 (5 pages)
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Nitric oxide에 의해 산화적 스트레스를 받은 Neuronal cell에 항산화 효과를 가지는 수종 생약추출물의 검색
구억, 이학주, 이동호, 이현정, 함아롬, 조은영, 마응천, Koo. Uk, Lee. Hak-Ju, Lee. Dong-Ho, Lee. Hyun-Jung, Ham. Ah-Rom, Cho. Eun-Young, Mar. Woong-Chon 한국생약학회 생약학회지 5 Pages
한국생약학회 생약학회지 2008, Vol.39 No.4 290-294 (5 pages)
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Effects of Curcumin, the Active Ingredient of Turmeric(Curcuma longa), on Regulation of Glutamate-induced Toxicity and Activation of the Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) in HT22 Neuronal Cell
Lee. Sang-Hyun, Yun. Young-Gab 한국생약학회 Natural product sciences 5 Pages
한국생약학회 Natural product sciences 2009, Vol.15 No.1 32-36 (5 pages)
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Protection of NMDA-Induced Neuronal Cell Damage by Methanol Extract of Myristica Fragrans Seeds in Cultured Rat Cerebellar Granule Cells
Ban. Ju-Yeon, Cho. Soon-Ock, Kim. Ji-Ye, Bang. Kyong-Hwan, Seong. Nak-Sul, Song. Kyung-Sik, Bae. Ki-Whan, Seong. Yeon-Hee 한국생약학회 Natural product sciences 7 Pages
한국생약학회 Natural product sciences 2004, Vol.10 No.6 289-295 (7 pages)
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LP-M, a Novel Butanol-Extracts Isolated from Liriope platyphylla, could Induce the Neuronal Cell Survival and Neuritic Outgrowth in Hippocampus of Mice through Akt/ERK Activation on NGF Signal Pathway
남소희, 최선일, 구준서, 김지은, 이연경, 황인식, 이혜련, 이영주, 이홍구, 최영환, 황대연, Nam. So-He, Choi. Sun-Il, Goo. Jun-Seo, Kim. Ji-Eun, Lee. Yoen-Kyung, Hwang. In-Sik, Lee. 한국생명과학회 생명과학회지 10 Pages
한국생명과학회 생명과학회지 2011, Vol.21 No.9 1234-1243 (10 pages)
맥문동(Liriope platyphylla)은 동양의학에서 오래 동안 항염증제, 당뇨 혹은 비만 치료제, 그리고 신경세포활성화 약제로 사용되어 왔다. 본 연구에서는 맥문동으로부터 NGF의 발현을 촉진하는 새로운 물질을 개발하고 이들의 작용기전을 밝히기 위하여 맥문동으로부터 13가지의 새로운 추출물을 확보하고 이들의 기능을 세포주와 마우스 실험을 통해 분석하였다. 그 결과, 상대적으로 세포독성이 낮고 NGF의 분비량이 많은 LP-E, LP-M, LP-M50, LP2E17PJ 등 4가지 추출물을 확보하였다. 또한 이들 중에서 LP2E17PJ를 제외한 3가지... -
Neuronal Cell Protection Activity of Macrolactin A Produced by Actinomadura sp.
Kim. Hyeon-Ho, Kim. Won-Gon, Ryoo. In-Ja, Kim. Chang-Jin, Suk. Jae-Eun, Han. Kyou-Hoon, Hwang. Se-Young, Yoo. Ick-Dong 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1997, Vol.7 No.6 429-434 (6 pages)
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Neuronal Cell Death of Abdominal Ganglia ($A_3$) and Characterization of Neuron - Killing Factor in Ventral Nerve Cord from Sweet Potato Hornworm, Agrius convolvuli
Kim. Mi-Kyung, Lee. Myoung-Hwan, Seo. Dong-Hwan, Choi. Chi-Won, Yun. Chi-Young 한국곤충학회 Korean journal of entomology 8 Pages
한국곤충학회 Korean journal of entomology 2002, Vol.32 No.4 261-268 (8 pages)
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Brief comparison of the mechanism of modern medicine and traditional medicine in neuronal cell death
Kim. Young-Sick, Jeong. Hyun-Ja, Kim. Hyung-Min, Cho. Seung-Hun 탕정한의학회 TANG : International journal of genuine traditional medicine 2 Pages
탕정한의학회 TANG : International journal of genuine traditional medicine 2011, Vol.1 No.1 1-2 (2 pages)
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Regulatory roles of ganglioside GQ1b in neuronal cell differentiation of mouse embryonic stem cells
Kwak. Dong-Hoon, Jin. Jung-Woo, Ryu. Jae-Sung, Ko. Kinram, Lee. So-Dam, Lee. Jeong-Woong, Kim. Ji-Su, Jung. Kyu-Yong, Ko. Ki-Sung, Ma. Ji 생화학분자생물학회 BMB reports 6 Pages
생화학분자생물학회 BMB reports 2011, Vol.44 No.12 799-804 (6 pages)
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Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway
Infectious Disease Prevention and Control. National Institute for Viral Disease Control and Prevention. Chinese Center for Disea 생화학분자생물학회 BMB reports 6 Pages
생화학분자생물학회 BMB reports 2009, Vol.42 No.7 444-449 (6 pages)
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Transduced HSP27 protein protects neuronal cell death by enhancing FALS-associated SOD1 mutant activity
An. Jae-Jin, Lee. Yeom-Pyo, Kim. Dae-Won, Sohn. Eun-Joung, Jeong. Hoon-Jae, Kang. Hye-Won, Shin. Min-Jae, Kim. Mi-Jin, Ahn. Eun-Hee, Jang 생화학분자생물학회 BMB reports 6 Pages
생화학분자생물학회 BMB reports 2009, Vol.42 No.3 136-141 (6 pages)
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Effects of Bombusae concretio Salicea on $Amyloid-{eta}$-induced Neuronal Cell Toxicity and Lipid Peroxidation in Cultured Rat Astrocytes
이우헌, 정지천, Lee. Woo-Heon, Jeong. Ji-Cheon 대한한방내과학회 대한한방내과학회지 11 Pages
대한한방내과학회 대한한방내과학회지 1998, Vol.19 No.2 381-391 (11 pages)
천축황(天竺黃)은 한의학에서 청풍열(淸風熱)과 치담(治痰)하는 효능으로 중풍과 불어증(不語症)을 치료하는데 널리 사용되고 있다. 본 연구에서는 천축황(天竺黃)이 실험적인 치매(Alzheimer Disease; AD)를 유발시키는 물질로 알려진 $amyloid-{eta};(A{eta};peptide)$를 흰쥐의 신경세포의 일종인 astrocyte에 처리하여 그 세포독성과 보호효과 및 세포막 지질의 과산화에 미치는 영향을 검토하였다. 천축황(天竺黃)은 $A{eta}$에 의한 신경세포에 대한 손상을 억제하여 세포증식을 촉진하여 예방 및 보호효과를 나타내었다. 또한,... -
Sauchinone Reduces Oxygen-glucose Deprivation-evoked Neuronal Cell Death via Suppression of Intracellular Radical Production
Choi. In-Young, Yan. Hua, Park. Yong-Ki, Kim. Won-Ki 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 8 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2009, Vol.32 No.11 1599-1606 (8 pages)
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Valproic Acid Increases Expression of Neuronal Stem/Progenitor Cell in Spinal Cord Injury
Bang. Woo-Seok, Kim. Kyoung-Tae, Cho. Dae-Chul, Kim. Hye-Jeong, Sung. Joo-Kyung 대한신경외과학회 Journal of Korean neurosurgical society 6 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2013, Vol.54 No.1 8-13 (6 pages)
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모단피의 PC12 cell 산화억제 효과 및 neuronal 유전자 발현 profile 분석에 대한 연구
김현희, 노삼웅, 나영인, 배현수, 신민규, 김정숙, 홍무창, Kim. Hyun Hee, Rho. Sam Woong, Na. Youn Gin, Bae. Hyun Su, Shin. Min Kyu, Kim. Chung Suk, Hong. Moo Chang 대한동의생리학회 동의생리병리학회지 13 Pages
대한동의생리학회 동의생리병리학회지 2003, Vol.17 No.2 529-541 (13 pages)
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Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by silica nanomaterials in human neuronal cell line
Kim. Youn-Jung, Yu. Mi-Ri, Park. Hee-Ok, Yang. Sung-Ik 대한독성유전단백체학회 Molecular & cellular toxicology 8 Pages
대한독성유전단백체학회 Molecular & cellular toxicology 2010, Vol.6 No.4 337-344 (8 pages)
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신경세포가 별아교세포의 아교섬유성 산단백질 표현에 미치는 영향 Effect of Glial-neuronal Cell Co-culture on GFAP Expression of Astrocytes
배형미, 박정선, 연동수, HyungmiBae, JungsunPark, DongsooYeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.3 7 285-296 (12 pages)
a neuronal influence on glial cell differentiation, maturation and function. The aim of the present study was to analyze the effects of glial-hippocampal neuronal co-culture on GFAP expression in the co-cultured astrocytes. The following antibodies were used for double immunostaining chemistry; mouse monoclonal antibodies for confirm neuronal cells, rabbit anti GFAP antibodies for confirm astrocytes. Primary cultured astrocytes showed the typical flat polygonal morphology in culture and... -
Notch, Snail, and Polycomb Repressive Complex 2 SupportHuman Mesenchymal Stem Cell Migration by High Glucose
Ji Young Oh, Jung Min Ryu, Sei Jung Lee, Hyun Jik Lee, Eun Ju Song, Ki Hoon Lee, Dah Ihm Kim, Jeong Yeon Kim, Gee Euhn Choi, So Hee Ko, Ho 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 271 483-483 (1 pages)
