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전체 선택해제
총 415건 검색
본문검색 결과만 보기
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Determination of Reorganization Energy from the Temperature Dependence of Electron Transfer Rate Constant for Hydroquinone-tethered Self-assembled Monolayers (SAMs)
Park. Won-choul, Hong. Hun-Gi 대한화학회 Bulletin of the Korean Chemical Society 5 Pages
대한화학회 Bulletin of the Korean Chemical Society 2006, Vol.27 No.3 381-385 (5 pages)
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Temperature Dependence of the Rate Constants of the VV Energy Exchange for N$_2$(v=1)+O$_2$(v=0)$ ightarrow$N$_2$(v=0)+O$_2$(v=1)
Ree. Jong-Baik, Chung. Keun-Ho, Kim. Hae-Jin 대한화학회 Bulletin of the Korean Chemical Society 5 Pages
대한화학회 Bulletin of the Korean Chemical Society 1986, Vol.7 No.3 241-245 (5 pages)
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Etch Rate Dependence of Differently Doped Poly-Si Films on the Plasma Parameters
박성호, 김윤태, 김진섭, 김보우, 마동성, Park. Sung-Ho, Kim. Youn-Tae, Kim. Jin-Sup, Kim. Bo-Woo, Ma. Dong-Sung 대한전자공학회 전자공학회논문지 8 Pages
대한전자공학회 전자공학회논문지 1988, Vol.25 No.11 1342-1349 (8 pages)
플리즈마 변수로서 가스조성과 압력 및 RF 전력이 인 및 붕소가 각각 다른 양으로 주입된 다결정 실리콘의 식각율 변화에 미치는 영향을 고찰하였다. $POCl_3$에 의해 인이 주입된 경우, 염소조성보다 불소조성이 많은 영역, 즉 $Cl_2$와 $SF_4$의 비가 17대 33일 때, 가장 큰 비등방성과 가장 작은 선폭손실을 달성하였다. 플라즈마 조건에 관계없이 주입된 불순물 농도의 증가에 다라, 인이 주입된 경우는 식각율이 증가하였고, 붕소가 주입된 경우는 식각율이 반대로 감소하였다. 또한, 급속 열처리에 의한 활성화 시간의 함수로서... -
Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats
BombiLee, BongjunSur, MijungYeom, InsopShim, HyejungLee, Dae-HyunHahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 2 379-386 (8 pages)
The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic morphine withdrawal in rats. Male rats were exposed to chronic, intermittent, escalating morphine (10∼50 mg/kg) for 10 days. After the last morphine injection, depression- and anxiety-like beahvior associated with morphine discontinuation persisted for... -
Temperature dependence of yield stress of Al-Li alloy
H.S.Shin, C.S.Oh 한국열환경공학회 한국열환경공학회 학술대회지 3 Pages
한국열환경공학회 한국열환경공학회 학술대회지 2014년 춘계 40 231-233 (3 pages)
Al-Li 2원계 합금의 석출과정은 Silcock 등이 X선을 이용하여 최초로 보고하였다. 과 포화고용체를 δ‘(Al3Li)에서 δ(AlLi)의 과정을 거치면서 δ’상의 석출에 의해 경 화된다. Al-Li합금계의 강화상인 δ‘상과 같은 L12형 규칙구조를 갖는 금속간 화합물 은 온도가 상승함에 따라 강도가 상승한다. 또한 Ni3Al을 기본으로 하는 화합물의 상 은 Ni기 초내열합금 조직의 기본적인 구상으로 되어 있으며 δ’상에도 동일한 효과가 기대된다. 본 연구에서는 Al-Li 합금의 기본적인 변형특성을 파악하기 위해 여러 Aging상태의 Al-L 2원계... -
Tension-Compression Asymmetry in the Off-Axis Nonlinear Rate-Dependent Behavior of a Unidirectional Carbon/Epoxy Laminate at High Temperature and Incorporation into Viscoplasticity Modeling
Kawai. M., Zhang. J.Q., Saito. S., Xiao. Y., Hatta. H. 한국복합재료학회 Advanced composite materials : the official journal of the Japan Society of Composite Materials and 21 Pages
한국복합재료학회 Advanced composite materials : the official journal of the Japan Society of Composite Materials and 2009, Vol.18 No.3 265-285 (21 pages)
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Comparison of rhythmic and non-rhythmic aerobic exercises on depression and balance in the elderly
Il-Ho Kwon, Jun-Young Song, Do-Ye Kim, Je-Yeong Son, Yu-Jin Shim, Won-Seob Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 3호 7 146-151 (6 pages)
Objective: The purpose of this study was to investigate the effects rhythmic and non-rhythmic aerobic exercises on depression and balance of healthy elderly people. Design: Randomized controled trial. Methods: Nineteen older subjects were randomly divided into 2 groups for rhythmic and non-rhythmic aerobic exercises. Both aerobic exercises consisted of functional movements such as turning in opposite directions, and running in place, the exercise consisted of movements that could activate... -
Effects of corrective exercises on selective functional movement assessment and health risk appraisal in middle-aged women
Jae Eun Kim, Cheong Kim, Sin-seop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 4 185-192 (8 pages)
Objective: The purpose of this study was to find the limited patterns of middle-aged women in selective functional movement evaluation and analyze the effects of pattern improvement exercises and general control groups on the Health Risk Appraisal (HRA). Design: Randomized controlled trial. Methods: The 31 subjects were physically healthy middle-aged women aged 40-59 living in Seoul, The subjects were randomly divided into an experimental group and a control group. Forty-three physically healthy... -
The effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients
Jin Shin, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 9 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 6 94-102 (9 pages)
Objective: The purpose of this study is to investigate the effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients. Design: Randomized controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited in Gyeongin Rehabilitation Center Hospital, located in Incheon. Patients who were enrolled in this study were randomized to experimental group (n=15) or control group (n=15). Treadmill with... -
Effect of low intensity pulsed ultrasound in activating the mitogen-activated protein kinase signaling pathway and inhibition inflammation cytokine synthesis in chondrocytes
Eun-Jung Kim, Gye-Yeop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 6 33-37 (5 pages)
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The effects of therapeutic ultrasound stimulation on the inflammation cytokine in rat articular chondrocytes
Eun-Jung Kim, Su-jin Hwang, Gye-Yeop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 4 21-26 (6 pages)
Objective: The aim of this study was to investigate the effect of therapeutic ultrasound (US) of cell viability and inflammatory cytokine in rat articular chondrocyte cultures stimulated with lipopolysaccharide (LPS). Design: One group pretest-posttest design. Methods: Cultured chondrocytes were treated with US and/or LPS and assessed for viability, Tumor necrosis factor (TNF)-α and Interleukin (IL)-1 production. Results: Oxidative stress was induced in rat chondrocytes with LPS. The cell... -
The effect of a water exercise on gait characteristics in the elderly post stroke patients
Hee-Sung Lim, Suk-Min Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2012, 제 1권 제 1호 4 17-21 (5 pages)
Objective: To investigate the effect of long-term water exercise on gait parameters in the elderly post stroke patients. Design: One group pretest-posttest design. Methods: Twenty elderly post stroke patients (age: 56.5±10.1 years, height: 168.6±5.8 cm, body mass: 69.3±6.9 kg, handicapped level: 2.5±0.8) participated in this study. Participants took part in gait training of 1 hour per day, three days per week, for three months. Participants’ gaits were analyzed to find the effect of 3... -
Challenges of Effective Teaching of Chemistry in Secondary Schools of Nepal
Indra Raj Upadhyaya 경인교육대학교 교육연구원 The Journal of Education 15 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.2 5 55-69 (15 pages)
This study aims to find out the challenges of effective teaching of chemistry. It tries to explore the areas of challenges that chemistry teachers face for delivering the chemistry content effectively and to find out the student’s difficulties in catching the chemical understanding. The study performed among the purposively selected ten secondary level chemistry teachers of Kathmandu valley, Nepal. Information generated with the help of interview questionnaire and the responses of the teacher... -
Prevention and Intervention of Adolescents’ Maladaptive Internet use
Oh Yeon Ju 경인교육대학교 교육연구원 The Journal of Education 15 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.2 1 1-15 (15 pages)
This article presents the characteristics of addiction, cognitive behavior, and social cognitive perspectives, which are the mainstream views of maladaptive Internet use. As the academic branch dealing with mental health, such as psychology and psychiatry, first raised the issue of maladaptive Internet use and continued research, views in the context of mental health, such as addiction and cognitive behavior perspectives, have become mainstream. The mental health perspective, however, shows... -
Assessment of the replication efficiency of porcine reproductive and respiratory syndrome viruses (PRRSVs) in porcine alveolar macrophages (PAMs) at different age of host-pigs
Amina Khatun, Salik Nazki, A Rum Kang, Chang Gi Jeong, Jhung hyun Juhng, Byoung Joo Seo, Won Il Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 208 305-306 (2 pages)
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Integrated analysis of microRNA and mRNA expressions in peripheral blood leukocytes of Warmblood horses before and after exercise
Hang-Ah Kim, Myung-Chul Kim, Na-Yon Kim, Doug-Young Ryu, Hong-Seok Lee, Yongbaek Kim 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 13 99-106 (8 pages)
Exercise capacity is a valuable trait in horses, and it has been used as a horse selection criterion. Although exercise affects molecular homeostasis and adaptation in horses, the mechanisms underlying these effects are not fully described. This study was carried out to identify changes in the blood profiles of microRNAs (miRNAs) and mRNAs induced by exercise in horse leukocytes. Total RNAs isolated from the peripheral blood leukocytes of four Warmblood horses before and after exercise were... -
Serum IGFBP4 concentration decreased in dairy heifers towards day 18 of pregnancy
Marie M Meyerholz, Kirsten Mense, Michael Lietzau, Ana Kassens, Matthias Linden, Hendrike Knaack, Elisa Wirthgen, Andreas Hoefli 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 4 413-421 (9 pages)
This study was conducted to determine if the main components of the somatotropic axis change during the early phase of pregnancy in the maternal blood system and whether differences exist on day 18 after pregnancy recognition by the maternal organism. Blood samples of pregnant heifers (Holstein Friesian; n = 10 after embryo transfer) were obtained on the day of ovulation (day 0), as well as on days 7, 14, 16 and 18 and during pregnant, non-pregnant and negative control cycles. The concentrations... -
Pulsed tissue Doppler imaging of the left ventricular septal mitral annulus in healthy dogs
Jihye Choi, Hyunwook Kim, Junghee Yoon* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 12 85-90 (6 pages)
This study evaluated pulsed TDI variables including the isovolumic time interval and duration of the major wave in a population of large healthy dogs. Longitudinal myocardial motion at the septal mitral annulus was evaluated with pulsed TDI in 45 healthy adult dogs. Maximal myocardial velocities, isovolumic time intervals, and duration of the myocardial waves were measured. The correlation between time intervals and velocity variables was also investigated. The mean maximal systolic velocity was... -
Implantation of canine umbilical cord blood-derived mesenchymal stem cells mixed with beta-tricalcium phosphate enhances osteogenesis in bone defect model dogs
Byung-Jun Jang, Ye-Eun Byeon, Ji-Hey Lim, Hak-Hyun Ryu, Wan Hee Kim, Yoshihisa Koyama, Masanori Kikuchi, Kyung-Sun Kang*, Oh-Kye 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 8 387-394 (8 pages)
This study was performed to evaluate the osteogenic effect of allogenic canine umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) mixed with beta-tricalcium phosphate (b-TCP) in orthotopic implantation. Seven hundred milligrams of b-TCP mixed with 1 × 10 UCB-MSCs diluted with 0.5 ml of saline (group CM) and mixed with the same volume of saline as control (group C) were implanted into a 1.5 cm diaphyseal defect and wrapped with PLGC membrane in the radius of Beagle dogs.... -
Protective effect of the isoflavone equol against DNA damage induced by ultraviolet radiation to hairless mouse skin
Sitarina Widyarini 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 2 217-223 (7 pages)
of CPDs immediately after SSUV irradiation or at 1 hour afterwards, but there were significant reductions of 23% and 42% at 24 and 48 h after SSUV exposure, respectively. Despite apparently reducing the number of CPDs post-SSUV, topically applied equol did not appear to increase the rate of dimer removal. To conclude, equol applied topically prior to SSUV irradiation offers protection against CPD formation in hairless mice, possibly by acting as a suncreen and thus inhibiting DNA photodamage. -
Isolation and characterization of Streptococcus sp.from diseased flounder (Paralichthys olivaceus )in Jeju Island
Gun Wook Baeck, Ji Hyung Kim, Dennis Kaw Gomez, Se Chang Park 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 9 53-58 (6 pages)
Streptococcus sp.is gram-positive coccus that causes streptococcal infections in fish due to intensification of aquaculture and caused significant economic losses in fish farm industry.A streptococcal infection occurred from cultured diseased olive flounder (Paralichthys olivaceus )in May, 2005 at a fish farm in Jeju Island, Korea.The diseased flounder exhibited bilateral exophthalmic eyes and rotten gills;water temperature was 16~18oC when samples were collected.Of the 22 fish samples... -
Effects of Protein Source and Energy Substrates on the In Vitro Development of Bovine Embryos in a Two-step Culture System
Kwang-taek Lim, Byeong-chun Lee, Sung-keun Kang, Woo-suk Hwang 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 1호 11 73-78 (6 pages)
In this study, we examined the effects of a two-step culture system, which involves the use of different culture media for early cleavage and later stage embryos, on the in vitro development of bovine embryos. We also investigated the effect of glucose, phosphate and citrate on the in vitro early developmental period of bovine embryos in a two-step culture system. Moreover, the supplementation of different protein sources (BSA-V, BSA-FAF and FBS) during IVC did not affect the frequency of... -
Biological Rhythm in Livestock
Piccione Giuseppe and Caola Giovanni 대한수의학회 Journal of Veterinary Science 13 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 1 145-157 (13 pages)
The animal time structure is a basic fact of life, no matter if one wants to study it or not. The time-dependent, mostly rhythmic, and thus to a certain degree predictable, variations of biochemical and physiological functions and of sensitivity and resistance to many environmental agents are often quite large and offer not only new insight into animal physiology and pathology but also diagnostic possibilities and therapeutic advantages. Chronobiology, chronophysiology and its subspecialities,... -
Isolation and characterization of Brucella abortus isolates from wildlife species in South Korea
Quang Lam Truong , Kiju Kim , Jong-taek Kim , Moon Her , Suk-chan Jung , Tae-wook Hahn 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 3호 3 147-153 (7 pages)
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Original Article : Comparison of antibiotic resistance profiles for Escherichia coli isolated from wild boar and domestic pig fecal samples
Sung J. Yoo , Sun Young Sunwoo , Sang Won Seo , Young S. Lyoo , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 1호 6 41-46 (6 pages)
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풍납토성 축조연대의 고고과학적 연구
이성준(Sungjoon Lee), 김명진(Myungjin Kim), 나혜림(Hyerim Na) 한국고고학회 한국고고학보 30 Pages
한국고고학회 한국고고학보 2013, 제 88집 2 42-71 (30 pages)
고고층서학적 정보는 유적의 형성 및 후퇴적과정을 이해하기 위한 고고자료의 시계열을 제공하고, 자연과학적 절대연대의 정밀도를 향상시키는 데 기여할 수 있다. 특히 고고학적 계기성을 사전확률모형으로 채택하는 베이지안 통계학은 고고자료의 시간적 순서(상대연대)를 자연과학적으로 뒤바꾸거나 타당성을 검토하는 것이 아니라, 고고자료와 공반된 연대자료를 토대로 물질문화의 변화폭보다 짧은 기간에 이루어진 인간행위의 시점을 검토하는 데 활용될 수 있다. 2011년 풍납토성 동성벽의 발굴조사에서는 해리스 매트릭스를... -
불소가 산부식된 법랑질의 재석회화에 미치는 영향에 관한 연구
김진한(Jin-Han Kim), 이기수(Ki-Soo Lee) 대한치과교정학회 The Korean Journal of Orthodontics 11 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 4호 6 389-399 (11 pages)
치과교정장치의 장착을 위하여 치아법랑질표면을 산부식하는 것은 일반화된 술식이며, 산부식된 법랑질표면은 재석회화되어 자연적으로 정상 상태를 회복하는 연구 보고 되어 왔다. 이 연구의 목적은 산부식된 법랑질 표면의 재석회화에 불소가 미치는 영향을 실험적으로 관찰하여 재석회화의 일면을 구명하는데 있다. 교정치료목적으로 발거한 사람 제1소구치 치관을, 불소함유 석회화용액과 불소무함유 석회화용액에 12시간, 1일, 3일, 7일, 14일, 28일, 42일간 담구어 보관한 후, 법랑질표면의 미세경도측정과 주사전자현미경 관찰을... -
Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
Yong Soo Park, Seok Ho Myeong, In-Beom Kim, Ki-Wug Sung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 12 585-595 (11 pages)
we simulated the 5-HT3 receptor currents using Berkeley Madonna？？ software and calculated the rate constants of the agonist binding and receptor transition steps. The 5-HT3 receptor currents were inhibited by amitriptyline in a concentration-dependent, voltage-independent manner, and a competitive mode. Amitriptyline accelerated the desensitization of the 5-HT3 receptor. When amitriptyline was applied before 5-HT treatment, the currents rose slowly until the end of 5-HT treatment. When... -
Antipruritic effect of curcumin on histamine-induced itching in mice
Han Kyu Lee, Seok Bum Park, Su-youne Chang, Sung Jun Jung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 8 547-554 (8 pages)
Itching is a common clinical symptom of skin disease that significantly affects a patient’s quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced... -
Conditioning-induced cardioprotection
Puneet Kaur Randhawa, Anjana Bali, Jasleen Kaur Virdi, Amteshwar Singh Jaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 1 467-479 (13 pages)
The aging process induces a plethora of changes in the body including alterations in hormonal regulation and metabolism in various organs including the heart. Aging is associated with marked increase in the vulnerability of the heart to ischemia-reperfusion injury. Furthermore, it significantly hampers the development of adaptive response to various forms of conditioning stimuli (pre/post/remote conditioning). Aging significantly impairs the activation of signaling pathways that mediate... -
Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel
HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 8 71-80 (10 pages)
the decay of Kv3.1 current. The paroxetine-induced inhibition of Kv3.1 channels was voltage-dependent even when the channels were fully open. The binding (k+1) and unbinding (k–1) rate constants for the paroxetine effect were 4.5 µM–1s–1 and 35.8 s–1, respectively, yielding a calculated KD value of 7.9 µM. The analyses of Kv3.1 tail current indicated that paroxetine did not affect ion selectivity and slowed its deactivation time course, resulting in a tail... -
Chronic Ca2+ influx through voltage-dependent Ca2+ channels enhance delayed rectifier K+ currents via activating Src family tyrosine kinase in rat hippocampal neurons
Yoon-SilYang, Sang-ChanJeon, Dong-KwanKim, Su-YongEun, Sung-CherlJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 14 259-265 (7 pages)
Excessive influx and the subsequent rapid cytosolic elevation of Ca2+ in neurons is the major cause to induce hyperexcitability and irreversible cell damage although it is an essential ion for cellular signalings. Therefore, most neurons exhibit several cellular mechanisms to homeostatically regulate cytosolic Ca2+ level in normal as well as pathological conditions. Delayed rectifier K+ channels (IDR channels) play a role to suppress membrane excitability by inducing K+ outflow in various... -
Calcium permeability of transient receptor potential canonical (TRPC) 4 channels measured by TRPC4-GCaMP6s
JuyeonKo, JongyunMyeong, DongkiYang, InsukSo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 16 133-140 (8 pages)
Conflicting evidence has been obtained regarding whether transient receptor potential cation channels (TRPC) are store-operated channels (SOCs) or receptor-operated channels (ROCs). Moreover, the Ca/Na permeability ratio differs depending on whether the current-voltage (I-V) curve has a doubly rectifying shape or inward rectifying shape. To investigate the calcium permeability of TRPC4 channels, we attached GCaMP6s to TRPC4 and simultaneously measured the current and calcium signals. A TRPC4... -
Voluntary stand-up physical activity enhances endurance exercise capacity in rats
DaeYunSeo, SungRyulLee, Hyo-BumKwak, KyoWonSeo, RobinAMcGregor, JiYoungYeo, TaeHeeKo, SaranhuuBolorerdene, NariKim, KyungSooKo, ByoungDooR 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 8 287-295 (9 pages)
Involuntary physical activity induced by the avoidance of electrical shock leads to improved endurance exercise capacity in animals. However, it remains unknown whether voluntary stand-up physical activity (SPA) without forced simulating factors improves endurance exercise capacity in animals. We examined the eff ects of SPA on body weight, cardiac function, and endurance exercise capacity for 12 weeks. Twelve male Sprague-Dawley rats (aged 8 weeks, n=6 per group) were randomly assigned to a... -
Blockade of Kv1.5 channels by the antidepressant drug sertraline
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 8 193-200 (8 pages)
Hill coefficient of 0.71 μM and 1.29, respectively. Sertraline accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between –20 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to +10 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance δ of 0.16. Sertraline slowed the deactivation time course, resulting...
