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Religious Conflicts, Pluralism, and Emptiness: A Madhyamika Buddhist View
Yongpyo Kim 한국종교교육학회 종교교육학연구 13 Pages
한국종교교육학회 종교교육학연구 2011, 제 35권 4 67-79 (13 pages)
The present study is concerned with the issues of Buddhist attitude toward religious pluralism from the M?dhyamika Buddhist perspective. This study focused on the following issues; (a) the relationship between religious conflict and exclusivism, (b) the general standpoint of Buddhism toward religious pluralism, (c) and the significance of the M?dhyamika view of emptiness(??nyat?)’ as harmonizing thought in an age of dialogue. Buddhism has consistently kept tolerant standpoint based on teaching... -
Hyperlipidemia as a predictor of physical functioning for stroke
Jae-hong Sim, Su-jin Hwang, Chiang-soon Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 8 88-93 (6 pages)
Objective: Elevated cholesterol levels contribute to changes of the arterial endothelial permeability. Hyperlipidemia promotes atherosclerosis and is associated with an increased risk of stroke incidence. The purpose of this study was to investigate the effects of having a history of hyperlipidemia prior to a stroke incidence on postural balance, anticipatory dynamic postural control, gait endurance and gait performance in individuals with hemiparetic stroke. Design: Cross-sectional study.... -
Reliability and validity of the patellofemoral disability index as a measure of functional performance and subjective pain in subjects with patellofemoral pain syndrome
Mastour Saeed Alshaharani, Everett Bernell Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Noha S. Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 3 61-66 (6 pages)
Objective: Patellofemoral pain syndrome (PFPS) is a condition that is characterized by patellar discomfort or pain that is aggravated during certain activities such as ascending/descending stairs. The Patellofemoral Disability Index (PDI) was developed to assess the effect of pain on functional activities in individuals with PFPS. The objectives of the current study were to determine the internal consistency, test-retest reliability, and validity of this index. Design: Cross-sectional study.... -
The effects of increased unilateral and bilateral calcaneal eversion on pelvic and trunk alignment in standing position
Jae-hoon Yi 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 5 84-88 (5 pages)
Objective: Generally, it is known that there is a correlation between excessive calcaneus eversion and a patient with low back pain and it also affects pelvic alignment. However, there are not enough studies that show calcaneal eversion having an effect on the alignment of the trunk. Design: Cross-sectional study. Methods: A 3-dimensional motion analysis system was used to assess the lower limbs, pelvic alignment, and trunk alignment with increased unilateral and bilateral calcaneal eversion in... -
Changes in pain, swelling, and range of motion according to physical therapy intervention after total knee arthroplasty in elderly patients
Eun-Kyung Noh, Chang-Sik An 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 4 79-86 (8 pages)
Objective: This study was carried out to compare changes in pain, swelling and range of motion (ROM) between the two groups according to physical therapy intervention. Design: Randomized controlled trial. Methods: There were a total of 20 elderly subjects ages 65-75 years old who have been admitted to the hospital for a total knee arthroplasty. After surgery, the experimental group (n=10) carried out quadriceps femoris muscle strengthening exercise, hamstring stretching exercises and... -
The effects of motor imagery training on brain waves in persons post-stroke
Hyang-Woon Yoon, Seong-Sik Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 10 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 1 1-10 (10 pages)
Objective: The purpose of this study was to investigate whether motor imagery training (MIT) combined with physical training could have a positive influence on brain waves in stroke patients. Design: Randomized controlled trial. Methods: Twenty-four survivors of a first-time stroke participated in the study. All patients were randomly assigned to one of two groups: (1) MIT group (n=12) and (2) control group (n=12). The MIT group participated in a total of 30 minutes of motor imagery (MI) on each... -
A Study on Assessment Design for In-class Debates - With a Focus on Case Analyses of Judging at World Debating Championships
Lee Sun Young, Park Joshua 경인교육대학교 교육연구원 The Journal of Education 20 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.2 7 85-104 (20 pages)
While debate has received broad acceptance as an important and effective tool for education, far less research attention has been paid to developing assessment designs for in-class debates. Existing studies on debate assessment has centered on examinations assessment elements and paradigms applied at domestic and US tournaments. This study goes beyond domestic or national settings to examine assessment at the highest levels of international competition, namely the World Schools Debating... -
The Management Strategy Private Schools in Vientiane Capital, Lao People’s Democratic Republic
Thongkham Thinnakone, Sroinam Somkid 경인교육대학교 교육연구원 The Journal of Education 11 Pages
경인교육대학교 교육연구원 The Journal of Education 2018, Vol.1 No.2 1 1-11 (11 pages)
The purpose of this research was to investigate the effective management strategies for private schools of basic education in Vientiane Capital, the Lao PDR. The qualitative method was used for this research such as document analysis, interviews and analysis techniques for the education of private schools. The results revealed four main and thirty-six auxiliary effective management strategies from those schools in Vientiane Capital were based on. Firstly, the result showed the relationships... -
Development of an immunochromatographic strip for detection of antibodies against porcine reproductive and respiratory syndrome virus
Huawei Li, Jifei Yang, Dengke Bao, Jie Hou, Yubao Zhi, Yanyan Yang, Pengchao Ji, Enmin Zhou, Songlin Qiao, Gaiping Zhang 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 7 307-316 (10 pages)
A simple and rapid immunochromatographic test strip incorporating a colloidal gold-labeled recombinant Nsp7 antigen probe was successfully developed for the detection of anti-porcine reproductive and respiratory syndrome virus (PRRSV) antibodies in swine. Recombinant Nsp7 protein of PRRSV labeled with colloidal gold was dispensed on a conjugate pad for use as the detector. Staphylococcal protein A and purified porcine anti-Nsp7 antibodies were blotted on a nitrocellulose membrane to form test... -
Immunologic properties of differentiated and undifferentiated mesenchymal stem cells derived from umbilical cord blood
Hyo-Jong Lee, Kyung-Sun Kang, Sun-Young Kang, Hyung-Sik Kim, Se-Jin Park, Seung-Yong Lee, Kwang-Dong Kim, Hee-Chun Lee, Ji-Kwon 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 4 289-297 (9 pages)
The expression of immunogenic markers after differentiation of umbilical cord blood (UCB)-derived mesenchymal stem cells (MSC) has been poorly investigated and requires extensive in vitro and in vivo testing for clinical application. The expression of human leukocyte antigen (HLA) classes on UCB-derived MSC was tested by Fluorescence-activated cell sorting analysis and immunocytochemical staining. The undifferentiated MSC were moderately positive for HLA-ABC, but almost completely negative for... -
Improved development of somatic cell cloned bovine embryos by a mammary gland epithelia cells in vitro model
Xiao-ying He, Li-bing Ma, Xiao-ning He, Wan-tong Si, Yue-Mao Zheng 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 3 145-152 (8 pages)
Previous studies have established a bovine mammary gland epithelia cells in vitro model by the adenovirus-mediated telomerase (hTERT-bMGEs). The present study was conducted to confirm whether hTERT-bMGEs were effective target cells to improve the efficiency of transgenic expression and somatic cell nuclear transfer (SCNT). To accomplish this, a mammary-specific vector encoding human lysozyme and green fluorescent protein was used to verify the transgenic efficiency of hTERT-bMGEs, and untreated... -
Chitosan hemostatic dressing for control of hemorrhage from femoral arterial puncture site in dogs
Viktor Szatm?ri 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 16 517-523 (7 pages)
Removal of an introducer-sheath from a femoral artery after completing transarterial embolization of a patent ductus arteriosus can cause life-threatening hemorrhage in dogs. In the present study, the effectiveness of chitosan acetate dressing in 10 experimental dogs was tested. Under general anesthesia, an introducer-sheath was placed into the femoral artery with percutaneous puncture using Seldinger’s technique. The outer diameter of the introducer-sheaths varied from 3.0 to 4.0 mm with an... -
Anaplasma sp. and hemoplasma infection in leopard cats (Prionailurus bengalensis euptilurus) from Korea
Jusun Hwang, Dae-Hyun Oh, Hang Lee, Myung-Sun Chun 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 18 385-388 (4 pages)
This study examined the occurrence of Anaplasma spp. and hemoplasma infection in leopard cats, Prionailurus bengalensis euptilurus, in Korea. Twenty-nine biological samples were tested by molecular analysis. Two (6.9%) and eight (27.6%) tested specimens were positive for Anaplasma bovis and hemoplasma infection, respectively. Based on our results, Anaplasma/Ehrlichia spp. and hemoplasma are regularly infecting leopard cat populations of Korea. Considering their endangered status, regular... -
Sporozoite proteome analysis of Cryptosporidium parvum by one-dimensional SDS-PAGE and liquid chromatography tandem mass spectrometry
AMAM Zonaed Siddiki* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 1 107-114 (8 pages)
Despite the development of new technologies, new challenges still remain for large scale proteomic profiling when dealing with complex biological mixtures. Fractionation prior to liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis is usually the preferred method to reduce the complexity of any biological sample. In this study, a gel LC-MS/MS approach was used to explore the stage specific proteome of Cryptosporidium (C.) parvum. To accomplish this, the sporozoite protein of C.... -
The effect of seasonal variation on anthrax epidemiology in the upper Zambezi floodplain of western Zambia
Hetron Mweemba Munang'andu*, Fredrick Banda, Victor Mukulule Siamudaala, Musso Munyeme, Christopher Jacob Kasanga, Byman Hamudud 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 11 293-298 (6 pages)
Anthrax has become endemic throughout the upper Zambezi floodplain located in the Western Province of Zambia over the recent years. To date, no comprehensive study has been carried out to determine whether recurrence of anthrax outbreaks may be linked to differences in precipitation and human activities. Retrospective data for the period 1999 to 2007 showed that a total of 1,216 bovine cases of anthrax were reported. During the same period, 1,790 human anthrax cases and a corresponding case... -
Comparison of four diagnostic methods for detecting rabies viruses circulating in Korea
Dong-Kun Yang*, Eun-Kyung Shin, Yoon-I Oh, Kyung-Woo Lee, Chung-San Lee, Seo-Young Kim, Jeong-A Lee, Jae-Young Song 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 1호 7 43-48 (6 pages)
It is essential to rapidly and precisely diagnose rabies. In this study, we evaluated four diagnostic methods, indirect fluorescent antibody test (FAT), virus isolation (VI), reverse transcriptase polymerase chain reaction (RT-PCR), and rapid immunodiagnostic assay (RIDA), to detect rabies in animal brain homogenates. Out of the 110 animal brain samples tested, 20 (18.2%) were positive for rabies according to the FAT. Compared to the FAT, the sensitivities of VI, RT-PCR, and RIDA were 100, 100,... -
Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors
Jung Min Ryu, Dong Hyun Kim, Min Young Lee, Sang Hun Lee, Jae Hong Park, Seung Pil Yun, Min Woo Jang, Seong Hwan Kim, Gyu Jin Rh 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 2호 1 93-98 (6 pages)
The shortage of organ donors has stimulated interest in the possibility of using animal organs for transplantation into humans. In addition, pigs are now considered to be the most likely source animals for human xenotransplantation because of their advantages over non-human primates. However, the appropriate standard values for estimations of the liver of micropigs have not been established. The determination of standard values for the micropig liver using multi-detector row computed tomography... -
Three-dimensional CT angiography of the canine hepatic vasculature
Yucheol Jeong, Changyun Lim, Sunkyoung Oh, Joohyun Jung, Jinhwa Chang, Junghee Yoon, Mincheol Choi* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 11 407-414 (8 pages)
Eight Beagle dogs were anesthetized and were imaged using a single channel helical CT scanner. The contrast medium used in this study was iohexol (300 mg I/ml) and doses were 0.5 ml/kg for a cine scan, 3 ml/kg for an enhanced scan. The flow rate for contrast material administration was 2 ml/sec for all scans. This study was divided into three steps, with unenhanced, cine and enhanced scans. The enhanced scan was subdivided into the arterial phase and the venous phase. All of the enhanced scans... -
Microbial pathogens in ticks, rodents and a shrew in northern Gyeonggi-do near the DMZ, Korea
Joon-Seok Chae, Do-Hyeon Yu, Smriti Shringi, Terry A. Klein, Heung-Chul Kim, Sung-Tae Chong, In-Yong Lee, Janet Foley 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 9 285-294 (10 pages)
A total of 1,618 ticks [420 individual (adults) and pooled (larvae and nymphs) samples], 369 rodents (Apodemus agrarius, Rattus norvegicus, Tscherskia triton, Mus musculus, and Myodes regulus), and 34 shrews (Crocidura lasiura) that were collected in northern Gyeonggi-do near the Demilitarized Zone (DMZ) of Korea during 2004-2005, were assayed by PCR for selected zoonotic pathogens. From a total of 420 individual and pooled tick DNA samples, Anaplasma (A.)phagocytophilum (16), A. platys (16),... -
The Safety and efficacy of a new self-expandable intratracheal nitinol stent for the tracheal collapse in dogs
Joon-young Kim, Hyun-jung Han, Hun-young Yun, Bora Lee, Ha-young Jang, Ki-dong Eom, Hee-myung Park, Soon-wuk Jeong* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 12 91-93 (3 pages)
To evaluate the potential utility of a self-expandable intratracheal nitinol stent with flared ends for the treatment of tracheal collapse in dogs, endotracheal stenting therapy was performed under fluoroscopic guidance in four dogs with severe tracheal collapse. During the 4 to 7 month followup, after stent implantation, clinical signs, including dyspnea and respiratory distress, dramatically improved in all dogs. The radiographs showed that the implanted stents improved the tracheal collapse,... -
An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korea
Jun Gu Choi, Youn Jeong Lee, *, Yong Joo Kim, Eun Kyoung Lee, Ok Mi Jeong, Haan Woo Sung, Jae Hong Kim, Jun Hun Kwon1 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 9 67-74 (8 pages)
The H9N2 subtype low pathogenic avian influenza is one of the most prevalent avian diseases worldwide, and was first documented in 1996 in Korea. This disease caused serious economic loss in Korea's poultry industry. In order to develop an oil-based inactivated vaccine, a virus that had been isolated in 2001 (A/chicken/Korea/01310/ 2001) was selected based on its pathogenic, antigenic, and genetic properties. However, in animal experiments, the efficacy of the vaccine was found to be very low... -
Application of a temporary palatal prosthesis in a puppy suffering from cleft palate
Jae-il Lee, Young-suk Kim, Myung-Jin Kim, Jieun Lee, Jong-hyup Choi, Dong-bok Yeom, Jung-mi Park, Sung-Hyeok Hong 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 19 93-95 (3 pages)
A 3-month-old Schnauzer was presented with congenital defects of the secondary palate.On the clinical examination, coughing, sneezing, drainage of nasal discharge from the external nares and poor growth were found.Vital signs and results of blood examination were within normal ranges.Thoracic radiography revealed mild pneumonia in the right lung lobes.In a puppy suffering from cleft palates, a palatal prosthesis was applied to the hard palate in order to protect the surgical wound, because a... -
Expression of placenta growth factor mRNA in the rat placenta during mid-late pregnancy
Wan Sung Choi, Gyeong Jae Cho, Chung Kil Won, Phil Ok Koh 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 1 179-183 (5 pages)
The placenta is an essential organ that synthesizes several growth and angiogenic factors for its own growth as well as fetal development. It is known that the placenta growth factor (PlGF)is a member of the vascular endothelial growth factor family and is critical for placental growth and fetal development. However, there is little information regarding the expression pattern and cellular localization of PlGF mRNA in rat placenta during pregnancy. The aim of this study was to define the... -
Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta
Phil-Ok Koh, Chung-Kil Won, Hae-Sook Noh, Gyeong-Jae Cho, Wan-Sung Choi 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 1호 1 1-5 (5 pages)
Pituitary adenylate cyclase activating polypeptide (PACAP) was first isolated from ovine hypothalamus and was known to stimulate the release of growth factor in various cells. Recently, we reported the cellular localization of PACAP and its type I (PAC1 ) receptor in rat placenta during pregnancy. Placenta is a critical organ that synthesizes several growth factors and angiogenic factors for the fetal development and its own growth. However, there is little information regarding the cellular... -
Estimation of Paratuberculosis Prevalence in Dairy Cattle in a Province of Korea using an Enzyme-linked Immunosorbent Assay: Application of Bayesian Approach
Son-il Pak, Doo Kim, Mo Salman 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 1호 8 51-56 (6 pages)
To draw inferences about the sensitivity and specificity of the newly developed ELISA test for bovine paratuberculosis (PTB) diagnosis and posterior distribution on the prevalence of PTB in a province of Korea, we applied Bayesian approach with Gibbs sampler to the data extracted from the prevalence study in 1999. The data were from a single test results without a designated gold test. The prevalence estimates for PTB in study population ranged 3.2-5.3% for conservative and 6.7-7.1% for liberal,... -
Characterization and comparison of the pathogenicity of viscerotropic velogenic Newcastle disease virus isolates in Korea
Jae Hong Kim , Haan Woo Sung , Il Hwan Kim , Eun Kyoung Lee , Kang Seuk Choi , Daniel Jack King 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 4호 2 231-239 (9 pages)
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한국의 후기 구석기시대 자연환경
한창균(Changgyun Han) 한국고고학회 한국고고학보 44 Pages
한국고고학회 한국고고학보 2008, 제 66집 1 4-47 (44 pages)
이 논문에서 논의된 유적의 시기는 약 50~10 ka BP에 해당하며,그 범위 안에 속하는 것으로 검토된 유적은 약 20군데에 이른다. 이와 같은 유적에서 보고된 꽃가루 분석과 동물화석에 대한 연구성과는 한국의 후기 구석기시대 자연환경을 이해하는 데 도움을 준다. 대체로 약 40 ka BP보다 오래된 유적의 퇴적물은 서늘한 온대기후의 환경조건에서 형성되었을 가능성이 크다고 생각된다. 약 40 ka BP 무렵에는 풍기동 II화분대(약 43~38.5 ka BP)와 구낭굴 IIIb화분대(40.6~38.9 ka BP)의 경우에서 나타나듯이,그 이전 시기에 비하여... -
Arts Education and Instrumental Outcomes: An Introduction to Research, Methods and Indicators
Larry O Farrell, Margaret Meban 한국음악교육공학회 음악교육공학 59 Pages
한국음악교육공학회 음악교육공학 2004, 제 4호 1 1-59 (59 pages)
이 논문은 2004년 1월에 홍콩에서 개최된 예술교육의 Unesco 전문가들이 3일 동안 연구한 연구보고서이다. 이것은 학교 교과과정에 예술을 소개하는 방법에 초점이 맞춰져 있는 6곳의 지역적인 컨퍼런스 시리즈 중 마지막으로서 계획되었다. 앞선 연구모임은 2001년부터 2003년까지 남아프리카의 Grahamstown, 브라질의 Uberaba, 요르단의 Amman, 피지의 Nadi, 핀란드의 Helsinki에서 개최되었다. 예술교육의 성장을 격려하기 위한 위원회로서 Unesco는 1999년에 시작된 각 지역적 모임을 통합하기 위해 구성되었다. 2001년의 모임의... -
타악기를 활용한 놀이 음악수업 지도 방안
한국음악교육학회 음악교육연구 2022, 제 51권 제 1호 4 71-97 (27 pages)
본 연구는 초등학교 고학년 학생들을 대상으로 놀이 방식을 적용한 타악기 음악수업 방 안을 제시하는 것이 목적이다. 연구를 위해 일반 수업에 쓰이는 타악기를 비롯하여, 생활 도구, 신체 악기를 활용하였다. 사용된 타악기들은 각기 번호카드 놀이, 퀴즈, 스테이지 오버, 찾기, 맞추기, 조종 놀이에 사용된다. 놀이 방식을 적용한 타악기 음악수업은 리듬, 음정, 빠르기와 같 은 음악 개념학습을 재미 있는 방식으로 개념화할 수 있다. 또한 모둠 활동이 가능하기 때문에 협동 학습이 가능하다. 이러한 구성은 음악수업을 흥미로운... -
Analysis of Illustrations of Music Textbooks for 5th-6th Grade Elementary School Students
Moonjung Yoon 한국음악교육학회 음악교육연구 16 Pages
한국음악교육학회 음악교육연구 2021, 제 50권 제 2호 6 117-132 (16 pages)
The purpose of this study was to draw attention to the research of illustrations in music textbooks to encourage further studies, and to provide basic data and suggestions for future illustration studies. For this, 1390 illustrations in 16 music textbooks for 5th-6th graders in elementary school used since 2018. To conduct this study, analysis criterion was established based on prior research, which are the content areas of music education, type, function, and purpose of illustrations. According... -
The efficacy of combination treatment of gabapentin and electro-acupuncture on paclitaxel-induced neuropathic pain
MinJoonKim, JiHwanLee, JoUngJang, FuShiQuan, SunKwangKim, WoojinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 11 657-666 (10 pages)
Paclitaxel, a chemotherapeutic drug, induces severe peripheral neuropathy. Gabapentin (GBT) is a first line agent used to treat neuropathic pain, and its effect is mediated by spinal noradrenergic and muscarinic cholinergic receptors. Electro-acupuncture (EA) is used for treating various types of pain via its action through spinal opioidergic and noradrenergic receptors. Here, we investigated whether combined treatment of these two agents could exert a synergistic effect on paclitaxel-induced... -
Lamotrigine, an antiepileptic drug, inhibits 5-HT3 receptor currents in NCB-20 neuroblastoma cells
KiJungKim, SeungHyunJeun, Ki-WugSung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 4 169-177 (9 pages)
Lamotrigine is an antiepileptic drug widely used to treat epileptic seizures. Using whole-cell voltage clamp recordings in combination with a fast drug application approach, we investigated the effects of lamotrigine on 5-hydroxytryptamine (5-HT)3 receptors in NCB-20 neuroblastoma cells. Coapplication of lamotrigine (1~300 μM) resulted in a concentration-dependent reduction in peak amplitude of currents induced by 3 μM of 5-HT for an IC50 value of 28.2±3.6 μM with a Hill coefficient of... -
Toll-like Receptor 2 is Dispensable for an Immediate-early Microglial Reaction to Two-photon Laser-induced Cortical Injury In vivo
HeeraYoon, YongHoJang, SangJeongKim, SungJoongLee, SunKwangKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 9 461-466 (6 pages)
Microglia, the resident macrophages in the central nervous system, can rapidly respond to patho-logical insults. Toll-like receptor 2 (TLR2) is a pattern recognition receptor that plays a fundamental role in pathogen recognition and activation of innate immunity. Although many previous studies have suggested that TLR2 contributes to microglial activation and subsequent pathogenesis following brain tissue injury, it is still unclear whether TLR2 has a role in microglia dynamics in the resting...


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