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Neural Substrates of Motor Imagery: Event-related Functional MRI Study
Seung-Schik Yoo, Byung Gil Choi, Kyu-In Chung, Chang-Uk Lee 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 25 1247-1256 (10 pages)
연구목적: 본 연구의 목적은 가상운동 과정시 대뇌 어느 부위가 활성화되는지를 알아보기 위하여 사건-관련 기능적 자기 공명영상을 통해 평가하였다. 방 법: 9명의 오른손잡이 정상인들에게 뇌 전 영역을 포괄한 일련의 T2강조 자기공명 영상을 얻기 위해 1.5 Tesla 자 기공명 영상장치를 사용하였다. 음성 자극 신호에 따라 오른손을 쥐는 상상을 하게 한 후, 그 결과 발생하는 가상 운동과 연관된 혈중 산화 수준-의존성 신호 변화들을 측정하였다. 결 과: 측정된 자료를 group 분석한 결과 내측 상부 전두회, 설상엽, 도, 중 /... -
Analysis of Altered Baseline Brain Activity in Drug-Naive Adult Patients with Social Anxiety Disorder Using Resting-State Functional MRI
Changjian Qiu, Yuan Feng, Yajing Meng, Wei Liao, Xiaoqi Huang, Su Lui, Chunyan Zhu, Huafu Chen, Qiyong Gong, Wei Zhang 대한신경정신의학회 Psychiatry Investigation 9 Pages
대한신경정신의학회 Psychiatry Investigation 2015, 제 12권 제 3호 14 372-380 (9 pages)
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Evidence of Cortical Reorganization in a Monoparetic Patient with Cerebral Palsy Detected by Combined Functional MRI and TMS
장성호, Kwon. Yong-Hyun, Jang. Sung-Ho, Lee. Mi-Young, Byun. Woo-Mok, Cho. Yoon-Woo, Ahn. Sang-Ho 영남의대학술지편집위원회 영남의대 학술지 8 Pages
영남의대학술지편집위원회 영남의대 학술지 2005, Vol.22 No.1 96-103 (8 pages)
뇌성마비로 인해 오른 손에서 단부전마비를 호소하는 환자를 대상으로 기능적 자기공명영상 장치와 경두개 자기 자극기를 사용하여 운동신경의 회복기전을 연구하였다. 대상자는 21세 된 남자 환자로 오른손에 경미한 운동 기능의 손상을 보였고, 자기공명영상의 소견에서 좌반구의 precentral knob에서 병변을 보였다. 기능적 자기공명영상 촬영은 한 명의 대상자와 여덟 명의 정상인을 대상으로 표준화된 헤드코일을 사용하여 1.5 T의 장치에서 BOLD 기술을 적용하여 실시하였다. 대상자들의 운동 수행은 1 Hz 주기로 손가락의 굴곡과... -
Reliability of Stereotactic Coordinates of 1.5-Tesla and 3-Tesla MRI in Radiosurgery and Functional Neurosurgery
Kim. Hae Yu, Lee. Sun-Il, Jin. Seong Jin, Jin. Sung-Chul, Kim. Jung Soo, Jeon. Kyoung Dong 대한신경외과학회 Journal of Korean neurosurgical society 6 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2014, Vol.55 No.3 136-141 (6 pages)
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Outcome Evaluation with Signal Activation of Functional MRI in Spinal Cord Injury
Jung. Jong-Kwon, Oh. Chang-Hyun, Yoon. Seung-Hwan, Ha. Yoon, Park. So-Ra, Choi. Byung-Hyune 대한신경외과학회 Journal of Korean neurosurgical society 7 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2011, Vol.50 No.3 209-215 (7 pages)
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The effects of EMG-triggered functional electrical stimulation on upper extremity function in stroke patients
Young Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 1 1-6 (6 pages)
systematic literature search was performed to identify clinical trials evaluating the effects of EMG-triggered functional electrical stimulation (EMG-FES) and task-oriented EMG-triggered FES on the hand functions in stroke patients. Literature review was conducted with the following key words: hand function, functional electrical stimulation, task-oriented, stroke. Results: Ten clinical trials were included; 8 of them were randomized controlled trial, 1 was block-randomized, and 1 was a pre-post... -
Functional recovery and neural differentiation after transplantation of allogenic adipose-derived stem cells in a canine model of acute spinal cord injury
Hak-Hyun Ryu, Ji-Hey Lim, Ye-Eun Byeon, Jeong-Ran Park, Min-Soo Seo, Young-Won Lee, Wan Hee Kim, Kyung-Sun Kang*, Oh-Kyeong Kweo 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 1 273-284 (12 pages)
In this study, we evaluated if the implantation of allogenic adipose-derived stem cells (ASCs) improved neurological function in a canine spinal cord injury model. Eleven adult dogs were assigned to three groups according to treatment after spinal cord injury by epidural balloon compression: C group (no ASCs treatment as control), V group (vehicle treatment with PBS), and ASC group (ASCs treatment). ASCs or vehicle were injected directly into the injured site 1 week after spinal cord injury.... -
Human Cerebellar Activation during Painful Cold Stimulation:a Functional Magnetic Resonance Imaging Study
Seung-Schik Yoo, Byung Gil Choi, Chang Uk Lee, Bum Soo Kim, , Su Jung Yoon, Soo Jung Lee, Tae Kim, Jung Jin Kim, Chul Lee, In Ho Paik 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 16 727-733 (7 pages)
연구목적: 본 연구에서는 기능적 자기공명영상법(fMRI)을 이용하여 동통 한랭 자극 동안의 소뇌 활동정도를 알아보 았다. 방 법: 6명의 건강한 자원자들을 선발하여 1.5 Tesla MR scanner 안에 누워 있는 동안 그들의 좌측 손에 0~3℃의 얼음주머니를 올려놓아 동통 한랭 자극을 주었다. 자극과 연관된 BOLD(blood oxygenation level dependent) 반응을 평가하기 위해 일련의 susceptibility-weighted MR image를 측정하였고 대뇌활동 영 역을 시각화하고 정량화하는 statistical parametric map을 작성하였다. 결 과: 한랭 자극으로... -
Event-related 기능적 MRI 영상을 통한 얼굴인식과정에서 수반되는 무의식적인 인종구별
김정석, 김범수, 전신수, 정소령, 최보영, Kim. Jeong-Seok, Kim. Bum-Soo, Jeun. Sin-Soo, Jung. So-Lyung, Choe. Bo-Young 대한자기공명의과학회 대한자기공명의과학회지 7 Pages
대한자기공명의과학회 대한자기공명의과학회지 2005, Vol.9 No.1 43-49 (7 pages)
기능적 자기공명영상기법(functional MRI: fMRI)을 통해서 인간의 뇌에 대한 연구가 지난 수년 동안 활발하게 진행되어 왔다. 이러한 기능적 자기공명영상기법의 파라다임에는 Block-diagram 방법과 최근에 개발되어 이용되는 Event-related 방법이 있다. Block-diagram 방법은 여러 블록으로 구성하여 피험자들에게 자극을 인가하여 뇌의 반응신호들을 통해 뇌의 기능을 설명해 주는 데, 이러한 뇌의 기능이 얼굴인식과 관련하여 여러 조건을 포함한 자극인 경우 뇌의 인지 시스템을 설명을 해 주는 데 한계가 있다. 따라서... -
MRI(Magnetic Resonance Imaging)의 원리와 응용
한국자기학회 韓國磁氣學會誌 1996, Vol.6 No.4 272-276 (5 pages)
현상을 이용한 영상촬영법(Magnetic Resonance Imaging, MRI)은 1970년대초 Lauterber와 Damadian 교수가 처음 영상을 얻을 수 있다는 가능성을 제시한 이후 급속한 발전을 하여 1980년대 초에는 Moore와 Holland에 의해 의학분야에 응용 가능할 정도의 영상이 얻어졌다. 1980년대 중반부터 상용화 되었으며 최근 그 기법도 NMR현상과 연관된 파라미터인 $T_{1}$, $T_{2}$는 물론 혈류의 속도, 자화율, 확산(Diffusion), Perfusion의 영상기법을 비롯해 혈관조영술(MR Angiography), 뇌기능영상(Functional Imaging)등 과거에는 상상도 할... -
원가족의 역기능적 의사소통 방식으로 인해 대인기피증이 있는 딸에 대한 가족치료 사례연구:MRI의 의사소통모델과 Bowen의 가족체계이론 중심으로
유진희, 박태영 한국가족치료학회 가족과 가족치료 22 Pages
한국가족치료학회 가족과 가족치료 2015, 제 23권 제 1호 9 217-238 (22 pages)
본 연구는 대인기피증이 있는 딸의 문제로 어머니가 상담을 의뢰하여 개입한 가족치료 사례연구이 다. 본 연구에 참여한 가족은 부모, 남매로 구성된 4명이며, 상담은 총 10회기 실시하였다. 본 연구는 10회기의 상담축어록과 상담 시 기록한 메모를 근거로 형성된 범주들을 Miles와 Huberman(1994)이 제 안한 매트릭스와 네트워크 방법을 사용하여 분석하였다. 가족 내에서 대화상대가 없었던 딸은 마음 속의 이야기를 단 한 번도 솔직하게 내놓지 못했으며, 가족구성원들의 역기능적인 의사소통방식은 딸 의 문제를 더욱 악화시켰다.... -
삼차원 시각 자극을 이용한 f-MRI 연구
김치영, 박호종, 오승준, 안창범, Kim. C.Y., Park. H.J., Oh. S.J., Ahn. C.B. 대한자기공명의과학회 대한자기공명의과학회지 6 Pages
대한자기공명의과학회 대한자기공명의과학회지 2005, Vol.9 No.1 24-29 (6 pages)
Tesla MRI 시스템에서 얻었다. 결과 : 삼차원 시각 자극에 의하여 활성화된 뇌의 영역은 이차원 시각 자극과 동일하게 후두엽으로 나타났으며, 삼차원 시각 자극에 의한 활성영역이 이차원 시각 자극에 의한 영역 보다 약 $18\%$ 더 넓게 나타났다. 결론 : 사람은 양 눈을 사용하여 삼차원 물체를 인식한다. 삼차원 물체 인식은 스테레오스코픽 비젼에 기인하는데, anaglyph 를 이용하여 삼차원 시각 자극에 대한 뇌기능 영상을 3.0 Tesla MRI 시스템에서 수행하였다. 삼차원 시각 자극에 의하여 활성화된 뇌의 영역은 이차원 시각 자극과... -
Functional Abnormalities of HERG Mutations in Long QT Syndrome 2 (LQT2)
MasayasuHIRAOKA 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.5 1 367-371 (5 pages)
with wild type HERG to form the functional channel as the tetramer. Most of missense mutants with few exceptions could interact with wild type HERG to form functional tetramer and caused dominant negative suppression with co-injection with wild type HERG showing variable effects on current amplitude, voltage dependence, and kinetics of activation and inactivation. Two missense mutants at pore regions of HERG found in Japanese LQT2 (A614V and V630L) showed accentuated inward rectification due to... -
Receiver operating characteristic curve analysis of the timed up and go test as a predictive tool for fall risk in persons with stroke
Seung-yeop Lim, Byung-jun Lee, Wan-hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 2 54-60 (7 pages)
Objective: Persons with chronic stroke fall more often than healthy elderly individuals. The Timed Up and Go test (TUG) is used as a fall prediction tool, but only provides a result for the total measurement time. This study aimed to determine the optimal cut-off values for each of the 6 components of the TUG. Design: Retrospective study. Methods: Thirty persons with chronic stroke participated in the study. TUG evaluation was performed using a wearable miniaturized inertial sensor. Sensitivity,... -
Reliability and validity of a personal computer based muscle viewer for measuring upper trapezius and transverses abdominis muscle thickness
Ju-Ri Jeong, Ju Hee Han, Ji-Eun Cho, Wan-hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 8 155-161 (7 pages)
Objective: This study aimed to investigate the reliability and validity of a personal computer-based muscle viewer (PC-BMW) compared with that of a portable ultrasound (P-US) for measuring upper trapezius (UT) and transversus abdominis (TrA) muscle thickness at rest and during contraction. Design: Observational inter-rater reliability study. Methods: Fifty-five healthy participants (25 men, 30 women) participated in this study. PC-BMW and P-US were randomly measured at the UT and TrA muscles.... -
The effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients
Jin Shin, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 9 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 6 94-102 (9 pages)
Objective: The purpose of this study is to investigate the effect of treadmill gait training with patellar taping on gait abilities in chronic stroke patients. Design: Randomized controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited in Gyeongin Rehabilitation Center Hospital, located in Incheon. Patients who were enrolled in this study were randomized to experimental group (n=15) or control group (n=15). Treadmill with... -
Kinematic characteristics of grip force in patients with cervical spondylosis
Bum-suk Lee, Naoto Noguchi, Daiki Kakiage, Tsuneo Yamazaki 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 1 61-65 (5 pages)
Objective: The aim of this study was to objectively evaluate sensory disturbance in cervical spondylosis using grip force and investigate the relationship between the grip force and upper extremity function. Design: Cross-sectional study. Methods: Eleven cervical spondylosis patients with paresthesia conducted grip and lift tasks using a precision grip with the tips of the thumb and index finger on either side. The sum of the grip force used during the first four seconds was calculated and... -
The immediate effects of patellar taping on balance and gait ability in individuals with chronic stroke
Jin Shin, Mee-Hyang Mun, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 9 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 8 125-133 (9 pages)
Objective: The aim of this study is to investigate the effect of patellar taping on balance and gait abilities in chronic stroke patients. Design: Randomized placebo-controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited from R hospital. These study subjects were randomized to the experimental group (n=15) or placebo group (n=15). In the experimental group, patellar taping was applied while for the placebo group, placebo... -
Variations in lateral abdominal muscle thickness during abdominal drawing-in maneuver in three positions in a young healthy population
Young Jun Ko, Hyun Geun Ha, Ju ri Jeong, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 4 101-106 (6 pages)
Objective: To investigate the appropriate position for abdominal drawing-in maneuver (ADIM) exercise by rehabilitative ultrasound image. Design: Cross-sectional study. Methods: Twenty-eight young adults with no history of low back pain participated in the study. Three positions compared were crook lying position with hip 60o flexion, standing position with the feet hip width apart and knees straight, and saddle standing positionunsupported with the knees 20° flexed. Once in the appropriate... -
The effect of co-contraction exercises of abdominal bracing combined with ankle dorsiflexion on abdominal muscle thickness and strength in patients with chronic low back pain
Wenlan Chai, So Hee Lee, Yu Hyung Park 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 3 93-100 (8 pages)
Objective: The purpose of this study was to determine the effect of the abdominal bracing (AB) and abdominal bracing combined with ankle dorsiflexion (ABDF) on abdominal muscle thickness and strength in patients with chronic low back pain (LBP). Design: Two group pretest posttest design. Methods: Sixteen subjects were divided randomly into two group: ABDF group (n=8), and alone AB group (n=8). The ABDF group practiced AB exercise with additional ankle dorsiflexion. AB group practiced only AB... -
Effects of 3-dimensional balance trainer in combination with a video-game system on balance and gait ability in subacute stroke patients
Hyun Geun Ha, Young Jun Ko, Hwang Jae Lee, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 2 7-12 (6 pages)
Objective: The purpose of this study was to investigate the effects of a three dimensional balance trainer in combination with a video-game system and visual feedback on balance recovery and gait function in subacute stroke patients. Design: Randomized controlled trial. Methods: Twenty-three subacute stroke patients were assigned to either an experimental (n=12) or a control group (n=11) using a random permuted block design and sealed envelopes. The experimental group received additional... -
Evidence-based use of cold for plantar fasciitis
Michael S. Laymon, Jerrold S. Petrofsky, Faris Alshammari, Stacy Fisher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 3 75-80 (6 pages)
Objective: The purpose of this study was to examine the effect of cold applied the night before or in the morning on pain and symptoms of plantar fasciitis. Design: Experimental study. Methods: Thirty subjects with plantar fasciitis were recruited for this study. Subjects with plantar fasciitis either had no intervention, cold applied (20 minutes) at night before bed, or 20 minutes in the morning upon wakening. Plantar fascia tenderness and pain were evaluated. There were ten subjects in each... -
The changes of rectus abdominis muscle thickness according to the angle during active straight leg raise
Hwang Jae Lee, Kil Ho Shin, Sung Mi Byun, Hyeon Seo Jeong, Ji Su Hong, Su Ji Jeong, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 8 44-48 (5 pages)
Objective: The purpose of this study was to investigate changes of abdominal muscles thickness according to the angle during the active straight leg raise (ASLR) in young healthy subjects. Design: Cross sectional study. Methods: Twenty-three healthy university students (13 men and 10 women) voluntary participated to the study in S University. The ASLR was performed with the subject lying supine with lower extremities straight on a standard plinth, hands resting on the chest, and elbows on the... -
Injury and inflammation detection by the application of microcurrent through the skin
Timothy Hui-Jerrold Petrofsky 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 6 31-38 (8 pages)
Objective: To determine the efficacy and reliability of measuring direct current microcurrent applied through the skin to determine injury in the underlying tissues. Design: Case control study. Methods: First, microcurrent was measured as decreased blood flow induced hypoxia in healthy subjects. Next, reliability was assessed by measuring over ten days with set variations in pressure and distance between the electrodes. Finally, measurements over sprained ankle were compared to measurements over... -
Relationship of trunk muscle atrophy and provocation position in patients with chronic low back pain
Doo Chul Shin, Chang Ho Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2012, 제 1권 제 1호 6 28-32 (5 pages)
Objective: The purpose of this study is to compare chronic low back pain patients pain provocation position so as to identify the relevance with lumbar stabilizing muscles atrophy and pain provocation position. Design: Cross-sectional study. Methods: Fifty five chronic low back pain patients were participated in this study. Subjects were eligible for study participation if they were 35-55 years old and had experienced low back pain for more than 3 months. Subjects were questioned about pain and... -
Microglial involvement in the development of olfactory dysfunction
Yoojin Seo, Hyung-Sik Kim, Kyung-Sun Kang 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 1 319-330 (12 pages)
Olfactory impairment is the most common clinical manifestation among the elderly, and its prevalence increases sharply with age. Notably, growing evidence has shown that olfactory dysfunction is the first sign of neurodegeneration, indicating the importance of olfactory assessment an early marker in the diagnosis of neurological disorders. In this review, we describe the nature of olfactory dysfunction and the advantage of using animal models in olfaction study, and we include a brief... -
Novel vertebral computed tomography indices in normal and spinal disorder dogs
Jongsu Lim, Youngmin Yoon, Taesung Hwang, Hee Chun Lee 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 16 296-300 (5 pages)
This study was carried out to derive and evaluate reference computed tomography (CT)-based indices for normal canine spine. CT and magnetic resonance images were acquired from 12 clinically normal Beagle dogs (normal group) and 50 dogs with 56 spinal disorders (patient group). Image acquisition regions were cervical spine (C2-T1), thoracic spine (T1-T13), and lumbar spine (L1-L7). Measured indices were: the ratios of width to height of the spinal cord including the dura matter (CR) and of the... -
Magnetic resonance imaging characteristics of ischemic brain infarction over time in a canine stroke model
Sooyoung Choi, Daji Noh, Youngwhan Kim, Inseong Jeong, Hojung Choi, Youngwon Lee, Kija Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 17 137-143 (7 pages)
(MRI) results and changes in lateral ventricular size over time in a canine ischemic stroke model. T1- and T2-weighted (T1W, T2W) imaging and fluid-attenuated inversion recovery (FLAIR) sequence MRI were performed at 3 h and 3, 8, and 35 days after brain infarct induction. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) mapping were performed at 8 and 35 days. A total of 29 brain lesions were induced successfully in 12 of 14 beagle dogs. At 3 h, T2W and FLAIR detected... -
Evaluation of the ureteral jet in dogs by using color Doppler ultrasonography
Hyunjung Oh, Seongsoo Kim, Suyeon Kim, Jeosoon Lee, Sookyung Yun, Junghee Yoon, Joohyun Jung, Mincheol Choi 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 17 399-406 (8 pages)
Ureteral jets are the result of a forceful ejection of urine from the vesicoureteral junction into the urinary bladder. By using color Doppler ultrasonography (US), we aimed to identify distinct ureteral jets in dogs, provide insight into ureteral obstruction, and facilitate study of urodynamics and vesicoureteric sphincter function via pulsed Doppler US. Color Doppler US was applied to detect urinary flow from the right ureteral orifices in eight healthy beagles. Under anesthesia, 0.9% saline... -
Retrospective study of the clinical effects of acupuncture on cervical neurological diseases in dogs
Ching Ming Liu, Fang Chia Chang, Chung Tien Lin 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 10 337-345 (9 pages)
This study was conducted to evaluate new acupuncture protocols for the clinical treatment of cervical spinal cord diseases in 19 dogs. Three treatment options containing Jing-jiaji (cervical jiaji) were developed to treat neck pain, hemiparesis, and tetraparesis depending on the severity. The interval between the neurological disease onset and treatment (duration of signs), time to improvement after treatment, and recovery time were compared in dogs by body weight,... -
Induction of antibody and interferon-γ production in mice immunized with virus-like particles of swine hepatitis E virus
Young-Jo Song, Woo-Jung Park, Seul-Kee Lee, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Kun-Ho Seo, Young-Sun 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 15 575-578 (4 pages)
Virus-like particles (VLPs) composed of the truncated capsid protein of swine hepatitis E virus (HEV) were developed and immune responses of mice immunized with the VLPs were evaluated. IgG titers specific for the capsid protein of swine HEV were significantly higher for all groups of mice immunized with the VLPs than those of the negative control mice. Splenocytes from mice immunized with the VLPs also produced significantly greater quantities of interferon (IFN)-γ than interleukin (IL)-4 and... -
Clinical applications and characteristics of apparent diffusion coefficient maps for the brain of two dogs
Boeun Kim, Kangjae Yi, Sunyoung Jung, Seoyeon Ji, Mincheol Choi, Junghee Yoon* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 17 455-458 (4 pages)
Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) mapping are functional magnetic resonance imaging techniques for detecting water diffusion. DWI and the ADC map were performed for intracranial lesions in two dogs. In necrotizing leukoencephalitis, cavitated lesions contained a hypointense center with a hyperintense periphery on DWI, and hyperintense signals on the ADC maps. In metastatic sarcoma, masses including a necrotic region were hypointense with DWI, and... -
Effect of Harderian adenectomy on the statistical analyses of mouse brain imaging using positron emission tomography
Minsoo Kim, Sang-Keun Woo, Jung Woo Yu, Yong Jin Lee, Kyeong Min Kim, Joo Hyun Kang, Kidong Eom, Sang-Soep Nahm* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 18 157-161 (5 pages)
Positron emission tomography (PET) using 2-deoxy-2-[F] fluoro-D-glucose (FDG) as a radioactive tracer is a useful technique for in vivo brain imaging. However, the anatomical and physiological features of the Harderian gland limit the use of FDG-PET imaging in the mouse brain. The gland shows strong FDG uptake, which in turn results in distorted PET images of the frontal brain region. The purpose of this study was to determine if a simple surgical procedure to remove the Harderian gland prior to... -
Percutaneous transplantation of human umbilical cord-derived mesenchymal stem cells in a dog suspected to have fibrocartilaginous embolic myelopathy
Wook-Hun Chung, Seon-Ah Park, Jae-Hoon Lee, Dai-Jung Chung, Wo-Jong Yang, Eun-Hee Kang, Chi-Bong Choi, Hwa-Seok Chang, Dae-Hyun 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 4호 18 495-497 (3 pages)
The use of human umbilical cord blood-derived mesenchymal stem cells for cell transplantation therapy holds great promise for repairing spinal cord injury. Here we report the first clinical trial transplantation of human umbilical cord (hUCB)-derived mesenchymal stem cells (MSCs) into the spinal cord of a dog suspected to have fibrocartilaginous embolic myelopathy (FCEM) and that experienced a loss of deep pain sensation. Locomotor functions improved following transplantation in a dog. Based on... -
Improved rat spinal cord injury model using spinal cord compression by percutaneous method
Wook-Hun Chung, Jae-Hoon Lee, Dai-Jung Chung, Wo-Jong Yang, A-Jin Lee, Chi-Bong Choi, Hwa-Seok Chang, Dae-Hyun Kim, Hyo Jin Chun 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 13 329-335 (7 pages)
Here, percutaneous spinal cord injury (SCI) methods using a balloon catheter in adult rats are described. A balloon catheter was inserted into the epidural space through the lumbosacral junction and then inflated between T9-T10 for 10min under fluoroscopic guidance. Animals were divided into three groups with respect to inflation volume: 20 μL (n = 18), 50 μL (n = 18) and control (Fogarty catheter inserted but not inflated; n = 10). Neurological assessments were then made based on BBB score,... -
Sporozoite proteome analysis of Cryptosporidium parvum by one-dimensional SDS-PAGE and liquid chromatography tandem mass spectrometry
AMAM Zonaed Siddiki* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 1 107-114 (8 pages)
Despite the development of new technologies, new challenges still remain for large scale proteomic profiling when dealing with complex biological mixtures. Fractionation prior to liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis is usually the preferred method to reduce the complexity of any biological sample. In this study, a gel LC-MS/MS approach was used to explore the stage specific proteome of Cryptosporidium (C.) parvum. To accomplish this, the sporozoite protein of C.... -
Use of canine small intestinal submucosa allograft for treating perineal hernias in two dogs
A-Jin Lee, Wook-Hun Chung, Dae-Hyun Kim, Kyung-Pil Lee, Hyun Jung Suh, Sun Hee Do, Ki-dong Eom, Hwi-Yool Kim* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 16 327-330 (4 pages)
Here, we describe two dogs in which canine small intestinal submucosa (SIS) was implanted as a biomaterial scaffold during perineal herniorrhaphy. Both dogs had developed severe muscle weakness, unilaterally herniated rectal protrusions, and heart problems with potential anesthetic risks. Areas affected by the perineal hernia (PH) located between the internal obturator and external anal sphincter muscles were reconstructed with naive canine SIS sheets. In 12 months, post-operative complications... -
Syringomyelia in three small breed dogs secondary to Chiari-like malformation: clinical and diagnostic findings
Chul Park, Byeong-Teck Kang, Jong-Hyun Yoo, Hee-Myung Park* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 16 365-367 (3 pages)
Three small breed dogs were referred for the evaluation of neurologic deficits. Upon physical and neurologic examination, all dogs displayed hyperesthesia, pain, and neck stiffness. Magnetic resonance imaging was performed on the brain and spinal cord, and all three dogs presented Chiari- like malformations and syringomyelia. These dogs were treated with prednisolone and furosemide, and showed rapid improvement of clinical signs. Chiari malformations and syringomyelia were not improved because... -
Charting the proteome of Cryptosporidium parvum sporozoites using sequence similarity-based BLAST searching
A.M.A.M.Z. Siddiki*, Jonathan M. Wastling 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 5 203-210 (8 pages)
Cryptosporidium (C.) spp. are important zoonotic parasites causing widespread diarrhoeal disease in man and animals. The recent release of the complete genome sequences for C. parvum and C. hominis has facilitated the comprehensive global proteome analysis of these opportunistic pathogens. The well-known approach for mass spectrometry (MS) based data analysis using the BLAST tool (MS BLAST) is a database search protocol for identifying unknown proteins by sequence similarity to homologous... -
Evaluation of partial cranial cruciate ligament rupture with positive contrast computed tomographic arthrography in dogs
Sungyoung Han, Haengbok Cheon, Hangmyo Cho, Juhyung Kim, Ji-Houn Kang, Mhan-Pyo Yang, Youngwon Lee, Heechun Lee, Dongwoo Chang* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 9 395-400 (6 pages)
Computed tomographic arthrography (CTA) of four cadaveric canine stifles was performed before and after partial cranial cruciate ligament rupture in order to verify the usefulness of CTA examination for the diagnosis of partial cranial cruciate ligament rupture. To obtain the sequential true transverse image of a cranial cruciate ligament, the computed tomography gantry was angled such that the scanning plane was parallel to the fibula. True transverse images of cranial cruciate ligaments were... -
Comparison of cardiac function and coronary angiography between conventional pigs and micropigs as measured by multidetector row computed tomography
Young Keun Ahn, Jung Min Ryu, Hea Chang Jeong, Yun Hyeon Kim, Myung Ho Jeong, Min Young Lee, Sang Hun Lee, Jae Hong Park, Seung 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 1 121-126 (6 pages)
Pigs are the most likely source animals for cardiac xenotransplantation. However, an appropriate method for estimating the cardiac function of micropigs had not been established. Computed tomography (CT) analysis aimed at estimating cardiac function and assessing the coronary arteries has not been carried out in micropigs. This study determined the feasibility of evaluating cardiac function in a micropig model using multidetector row computed tomography (MDCT) and compared the cardiac function... -
Transplantation of canine umbilical cord blood-derived mesenchymal stem cells in experimentally induced spinal cord injured dogs
Ji-Hey Lim, Ye-Eun Byeon, Hak-Hyun Ryu, Yun-Hyeok Jeong, Young-Won Lee, Wan Hee Kim, Kyung-Sun Kang, Oh-Kyeong Kweon 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 12 275-282 (8 pages)
evoked potentials and histopathological examinations were used to evaluate the functional recovery after transplantation. The Olby scores of all groups were zero at the 0-week evaluation. At 2 week after the transplantation, the Olby scores in the groups with the UCB-MSC and UCBG were significantly higher than in the CN and CP groups. However, there were no significant differences between the UCB-MSC and UCBG groups, and between the CN and CP groups. These comparisons remained stable at 4 and 8... -
Surgical treatment of spinal cord compression in client owned dogs with different grades of neurological dysfunction
Maria Kuricova , Valent Ledecky , Tomas Liptak 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 2호 9 113-116 (4 pages)
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Diagnostic imaging of malignant insulinoma in a dog
Ji Hye Choi , Seo Yeon Keh , Sung Soo Kim , Su Hyung Lee , Hye Jin Kim , Hee Yeon Choi , Youn Ji Lim , Hyun Wook Kim , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 3호 9 205-208 (4 pages)
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Cerebellar maturation ratio of forebrain and brainstem at magnetic resonance imaging in the micropig
Kang Jae Yi , Jun Young Kim , Nam Soon Lee , Mi Hyun Choi , Jung Hee Yoon , Min Cheol Choi 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 2호 4 83-87 (5 pages)


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