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Voltage-gated $K^+$ channels contributing to temporal precision at the inner hair cell-auditory afferent nerve fiber synapses in the mammalian cochlea
Oak. Min-Ho, Yi. Eunyoung 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 13 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2014, Vol.37 No.7 821-833 (13 pages)
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Brainstem auditory evoked potential findings in a French bulldog with bilaterally congenital sensorineural deafness
Dae Gi An , Dong In Jung , Ha Jung Kim , Ji Houn Kang , Dong Woo Chang , Mhan Pyo Yang , Byeong Teck Kang 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 3 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2013, 제 53권 제 4호 13 265-267 (3 pages)
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Nitric Oxide Modulation of GABAergic Synaptic Transmission in Mechanically Isolated Rat Auditory Cortical Neurons
Jong-JuLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 9 461-467 (7 pages)
a transmitter molecule and can alter neural activity without direct synaptic connections. We used whole-cell recordings under voltage clamp to investigate the effect of NO on spontaneous GABAergic synaptic transmission in mechanically isolated rat auditory cortical neurons preserving functional presynaptic nerve terminals. GABAergic spontaneous inhibitory postsynaptic currents (sIPSCs) in the A1 were completely blocked by bicuculline. The NO donor, S-nitroso-N-acetylpenicillamine (SNAP), reduced... -
Changes in Vestibular Nerve Activity Following Acute Hypotension in Rats
ByungRimPark, MinSunKim, GueHyunYee, MyoungJinMoon, JaeHyoKim, YuanZheJin, YoSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 6 85-89 (5 pages)
simulating hemorrhage was a greater increase than in control animals. The gain of the vestibular nerve with sinusoidal rotation following acute hypotension increased significantly compared to control animals. The acute hypotension induced by SNP or hemorrhage did not change the activity of the afferent vestibular nerve after kynurenic acid injection. These results suggest that acute hypotension produced excitation of the vestibular hair cells via glutamate excitotoxicity in response to ischemia. -
Effect of Stimulus Rate and Gender on Auditory Brainstem Response in Korean Young Adults
Chul-Hee Choi, Ki-Hyeon Jang, Seong Hee Choi 한국청각언어재활학회 Audiology and Speech Research 16 Pages
한국청각언어재활학회 Audiology and Speech Research 2015, 제 11권 제 2호 5 140-155 (16 pages)
The main objective of this study was to determine the effect of stimulus rate and gender on auditory brainstem response (ABR) latency and amplitude in Korean young adults. A total of thirty young adults consisting of fifteen males and fifteen females participated in the study. We performed this study by analyzing the latencies and amplitudes of ABR wave I, Ⅲ, and V as a function of low stimulus rate and gender. The stimulus repetition rate was changed in five steps: 8, 16, 21, 32, and 64/s.... -
정상과 고심도 감각신경성난청에서 청성지속반응(Auditory Steady-State Response)에 영향을 주는 변수에 관한 고찰
조수진, 이정학, 김형종, 조소현, 임덕환, 김진숙 한국청각언어재활학회 Audiology and Speech Research 7 Pages
한국청각언어재활학회 Audiology and Speech Research 2005, 제 1권 제 1호 5 28-34 (7 pages)
청성지속반응(auditory steady-state response, ASSR)은 연속적인 음 자극(continuous acoustic stimuli)에 대한 청각전도로의 반응으로 특히 고심도 난청의 청력을 추정할 수 있는 대표적인 객관적 검사로 알려져 있다.12) 이러한 ASSR은 변조된 순음(pure tone)에 의해서 유발되기 때문에 청성뇌간반응(auditory brainstem response, ABR) 측정 시 주로 사용하는 클릭음(click)보다 와우의 좁은 부위를 자극하게 되어 주파수 특이성이 더 높고,9) 자동반응탐지 알고리즘(automatic response detection algorithm)을 사용하기 때문에... -
청각통합능력검사(Meaningful Auditory Integration Scale, MAIS)의 이해와 해석본 연구
김진숙, 김지민, 문형아, 박성혜, 박영덕, 배미란, 이미소, 이지연, 장선아, 장현숙, 허명진 한국청각언어재활학회 Audiology and Speech Research 26 Pages
한국청각언어재활학회 Audiology and Speech Research 2014, 제 10권 제 2호 2 99-124 (26 pages)
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ICR 마우스에서 Auditory Brainstem Response(ABR)의 Validation 연구
홍빛나, 박태규, 홍하나, 강동호 한국청각언어재활학회 Audiology and Speech Research 6 Pages
한국청각언어재활학회 Audiology and Speech Research 2008, 제 4권 제 1호 10 58-63 (6 pages)
방법은 크게 두 가지로 나뉘는데, 피검자의 반응이 필수적인 주관적 방법과, 피검자의 능동적참여가 필요치 않고 결과를 객관적으로 분석할 수 있는 객관적 방법이 있다.11) 객관적인 검사 중 청성유발전위(auditory evoked potential, AEP)검사는 청력선별검사, 청력역치의 추정, 청각신경계의 다양한 진단과 관련하여 많이 사용되고 있다. AEP는 전기생리학적으로 전달되는 청신경계의 전기신경자극을 두피에서 기록하여 청력의 손실유무, 손실의 정도와 유형, 손실의 부위를 진단하게 된다. AEP의 종류는 소리자극 후 반응이 나타나는... -
Effect of backward walking training using an underwater treadmill on muscle strength, proprioception and gait ability in persons with stroke
Dong-Min Kum, Won-Seob Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 3호 3 120-126 (7 pages)
Objective: The purpose of this study was to investigate the effects of backward treadmill gait training between underwater and ground environments on strength, proprioception, and walking ability in persons with stroke. Design: Randomized control trial. Methods: Twenty eight subjects participated in the study in which they were randomly assigned to either the underwater backward treadmill training (UBTT) group (n=13) or the BTT group (n=15). In both groups, forward gait training was performed... -
The effect of applying a head-weight device on cervical angle and pain of neck muscles
Jin-Hong Kim, Jong-Gun Kim, Kwang-Sun Do, Jong-eun Yim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 8 101-105 (5 pages)
Objective: The purpose of this study was to measure the change in pain threshold of levator scapular muscle, carniovertebral angle, and head position angle when applying a head-weight device on healthy adult. Design: Cross-sectional study. Methods: This study was conducted with 21 healthy adult male and female who voluntarily agreed to participate in this study after being informed of the purpose and method of this study. After measuring the cervical angle and pain threshold of levator scapular... -
Effects of mobile texting and gaming on gait with obstructions under different illumination levels
Jae-yun Cha, Hyun-jin Kim, Jae-myoung Park, Chang-ho Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 6 32-37 (6 pages)
Objective: This study was conducted to test the effects of mobile texting and gaming on gait with obstructions under different illumination levels. Design: Cross-sectional study. Methods: Twelve healthy adults aged 20 to 36 years (mean 23.5 years) were tested under six different conditions. All participants used touchscreen smartphones. Testing conditions included: 1) Walking with an obstruction under a bright illumination level; 2) walking with an obstruction with a low level of illumination;... -
Predicting Attention and Memory Ability based on the Combination of EEG and HRV data in Children
Hyeong Seok Jeon, Junhee Lee, June Lee, You Jin Hwang, Siyoung Lee, Hee Yang, Jung Han Yoon, Jun Soo Kwon, Jung Ho Won, Jun Dong Cho, Ki Won Lee 한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 8 Pages
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning 2019, 제 9권 제 3호 1 105-112 (8 pages)
Good performance is important element not only in workplace but also in daily activities. Performance of the human depends on the mental capacity and mental workload. Especially, children in concrete operational stage is critical for further learning ability that they develop their ability to distinguish between quality and quantity. However, the reason that mental workload is difficult to quantify through physiological measures, makes it more complicated to demonstrate the mental workload. When... -
구순구개열 및 가로얼굴파열을 동반한 Goldenhar Syndrome 환자에서 수술적 치료: 증례보고
박종열, 김준영, 박진후, 정휘동, 정영수 대한구순구개열학회 대한구순구개열학회지 6 Pages
대한구순구개열학회 대한구순구개열학회지 2019, 제 22권 1호 4 21-26 (6 pages)
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Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling
TaoJiang, Xiu-qinWang, ChuanDing, Xue-lianDu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 2 579-589 (11 pages)
Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic AMP response element-binding protein (CREB) are involved in learning and memory processes. Genistein, a plant-derived isoflavone, has been shown to exhibit neuroprotective effects. The present study... -
Effect of Stimulus Waveform of Biphasic Current Pulse on Retinal Ganglion Cell Responses in Retinal Degeneration (rd1) mice
KunNoAhn, JeongYeolAhn, Jae-hyungKim, KyoungrokCho, Kyo-inKoo, SolomonS.Senok, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 12 167-175 (9 pages)
A retinal prosthesis is being developed for the restoration of vision in patients with retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Determining optimal electrical stimulation parameters for the prosthesis is one of the most important elements for the development of a viable retinal prosthesis. Here, we investigated the effects of different charge-balanced biphasic pulses with regard to their effectiveness in evoking retinal ganglion cell (RGC) responses. Retinal... -
Potassium Currents in Isolated Deiters' Cells of Guinea Pig
JongWooChung, EuiCholNam, WonTaeKim, JaeBoumYoum, ChaeHunLeem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 10 537-546 (10 pages)
Deiters' cells are the supporting cells in organ of Corti and are suggested to play an important role in biochemical and mechanical modulation of outer hair cells. We successfully isolated functionally different K+ currents from Deiters’ cells of guinea pig using whole cell patch clamp technique. With high K+ pipette solution, depolarizing step pulses activated strongly outward rectifying currents which were dose-dependently blocked by clofilium, a class III anti-arrhythmic K+ channel blocker.... -
Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons
YunjuJin, JunKim, JiyeonKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 10 211-217 (7 pages)
Recent studies have demonstrated that nitric oxide (NO) activates transient receptor potential vanilloid subtype 1 (TRPV1) via S-nitrosylation of the channel protein. NO also modulates various cellular functions via activation of the soluble guanylyl cyclase (sGC)/protein kinase G (PKG) pathway and the direct modification of proteins. Thus, in the present study, we investigated whether NO could indirectly modulate the activity of TRPV1 via a cGMP/PKG-dependent pathway in cultured rat dorsal root... -
The Effects of Glutamate NMDA Receptor Antagonist MK-801 on Gastrointestinal Motility after Middle Cerebral Artery Occlusion in Rats
NasirHussinAmeer, JaeHeeLee, MyoungAeChoi, Guang-ShiJin, MinSunKim, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 6 151-156 (6 pages)
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Effects of Saccharin Intake on Hippocampal and Cortical Plasticity in Juvenile and Adolescent Rats
Jong-SilPark, SangBaeYoo, JinYoungKim, SungJoongLee, Seog-BaeOh, Joong-SooKim, Jong-HoLee, KyungpyoPark, JeongWonJahng, Se-YoungChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 8 113-118 (6 pages)
The sensory system is developed and optimized by experiences given in the early phase of life in association with other regions of the nervous system. To date, many studies have revealed that deprivation of specific sensory experiences can modify the structure and function of the central nervous system; however, the effects of sensory overload remains unclear. Here we studied the effect of overloading the taste sense in the early period of life on the synaptic plasticity of rat hippocampus and... -
Multiple Residues in the P-Region and M2 of Murine Kir 2.1 Regulate Blockage by External Ba2＋
YoungMeeLee, GarethA.Thompson, IanAshmole, MarkLeyl, InsukSo, PeterR.Stanfield 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 10 61-69 (9 pages)
We have examined the effects of certain mutations of the selectivity filter and of the membrane helix M2 on Ba2＋ blockage of the inward rectifier potassium channel, Kir 2.1. We expressed mutant and wild type murine Kir 2.1 in Chinese hamster ovary (CHO) cells and used the whole cell patch-clamp technique to record K＋ currents in the absence and presence of externally applied Ba2＋. Wild type Kir2.1 was blocked by externally applied Ba2＋ in a voltage and concentration dependent manner. Mutants... -
Temporal Changes of the Calcium-binding Proteins in the Medial Vestibular Nucleus following Unilateral Labyrinthectomy in Rats
SeokMinHong, JaeHeeLee, SeungGeunYeo, ChangIlCha, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 2 95-100 (6 pages)
Calcium (Ca2＋) is an intracellular second messenger associated with neuronal plasticity of the central nervous system. The calcium-binding proteins regulate the Ca2＋-mediated signals in the cytoplasm and buffer the calcium concentration. This study examined temporal changes of three calcium-binding proteins (calretinin, calbindin and parvalbumin) in the medial vestibular nucleus (MVN) during vestibular compensation after unilateral labyrinthectomy (UL) in rats. Rats underwent UL, and the... -
White Matter Damage and Hippocampal Neurodegeneration Induced by Permanent Bilateral Occlusion of Common Carotid Artery in the Rat: Comparison between Wistar and Sprague-Dawley Strain
Seul-KiKim, Kyung-OkCho, SeongYunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 1 89-94 (6 pages)
In order to reproduce chronic cerebral hypoperfusion as it occurs in human aging and Alzheimer's disease, we introduced permanent, bilateral occlusion of the common carotid arteries (BCCAO) in rats (Farkas et al, 2007). Here, we induced BCCAO in two different rat strains in order to determine whether there was a strain difference in the pathogenic response to BCCAO. Male Wistar and Sprague-Dawley (SD) rats (250-270 g) were subjected to BCCAO for three weeks. Klüver-Barrera and cresyl violet... -
Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats
Han-SeongJeong, HaeRyongHuh, Myung-JooJang, Seol-HeeHong, SujeongJang, JinPark, Seung-HanLee, Jae-HaKim, Jong-SeongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 3 131-136 (6 pages)
Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular nuclear neurons of rat by whole-cell patch-clamp technique. Sprague-Dawley rats, aged 14 to 16 days, were used. After enzymatic digestion, dissociated medial vestibular neurons were transferred to a recording chamber mounted on an inverted microscope, and spontaneous... -
Effects of a δ-opioid Agonist on the Brainstem Vestibular Nuclear Neuronal Activity of Rats
Tae-SunKim, MeiHuang, Myung-JooJang, Han-SeongJeong, Jong-SeongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.3 1 137-142 (6 pages)
This study was undertaken to investigate the effects of [D-Ala2, D-Leu5]-enkephalin (DADLE) on the spontaneous activity of medial vestibular nuclear neurons of the rat. Sprague-Dawley rats, aged 14 to 16 days, were anesthetized with ether and decapitated. After enzymatic digestion, the brain stem portion of medial vestibular nuclear neuron was obtained by micropunching. The dissociated neurons were transferred to a recording chamber mounted on an inverted microscope, and spontaneous action... -
Presynaptic Mechanism Underlying Regulation of Transmitter Release by G Protein Coupled Receptors
TomoyukiTakahashi, YoshinaoKajikawa, MasahiroKimura, NaotoSaitoh, TetsuhiroTsujimoto 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 1 69-76 (8 pages)
A variety of G protein coupled receptors (GPCRs) are expressed in the presynaptic terminals of central and peripheral synapses and play regulatory roles in transmitter release. The patch-clamp whole-cell recording technique, applied to the calyx of Held presynaptic terminal in brainstem slices of rodents, has made it possible to directly examine intracellular mechanisms underlying the GPCR-mediated presynaptic inhibition. At the calyx of Held, bath-application of agonists for GPCRs such as GABAB... -
Changes in Excitability of Neurons in Rat Medial Vestibular Nucleus Following Vestibular Neurectomy
SangWooChun, JeongHeeChoi, ShinHyungLee, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 2 287-291 (5 pages)
Intrinsic excitabilities of acutely isolated medial vestibular nucleus (MVN) neurons of rats with normal labyrinth and with undergoing vestibular compensation from 30 min to 24 h after unilateral vestibular deafferentation (UVD) were compared. In control rats, proportions of type A and B cells were 30 and 70%, respectively, however, the proportion of type A cells increased following UVD. Bursting discharge and irregular firing patterns were recorded from 2 to 12 h post UVD. The spontaneous... -
Neuronal Activity of the Vestibular Nuclei Following Acute Hypotension in Rats
ByungRimPark, MinSunKim, KumHyunBaik, MoonYoungLee, MyungAeChoi, JaeHyoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.4 5 199-206 (8 pages)
The role of peripheral vestibular receptors in acute hypotension was investigated in anesthetized rats. Acute hypotension was induced by either intravenous infusion of sodium nitroprusside (SNP) or by experimental hemorrhage, and electrical activity and expression of cFos-like immunoreactive (cFL) protein were measured in the medial vestibular nuclei (MVN). Blood pressure decreased proportionately to the does of intravenous SNP and to the volume of the hemorrhage. Blood pressure decreased 10,... -
Electrical Stimulation Can Facilitate Vestibular Compensation Following Unilateral Labyrinthectomy in Rats
ByungRimPark, JinOkKim, MinSunKim, MoonYoungLee, JaeHyoKim, Yuan-ZheJin, MyungAeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 2 123-131 (9 pages)
To investigate the effects of electrical stimulation on vestibular compensation, which is the recovery of vestibular symptoms following unilateral labyrinthectomy (UL), intermittent electrical stimulation was applied to the injured vestibular portion in Sprague-Dawley rats. Vestibuloocular and vestibulospinal reflexes, electrical activity and expression of c-Fos protein in medial vestibular nuclei (MVN) were measured with time following UL. Spontaneous nystagmus occurred with frequency of... -
Characteristic Intracelluar Response to Lidocaine And MK-801 of Hippocampal Neurons An In Vivo Intracellular Neuron Recording Study
Byung-JuChoiJin-HwaCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 4 297-305 (9 pages)
This study used in vivo intracellular recording in rat hippocampus to evaluate the effect of lidocaine and MK-801 on the membrane properties and the synaptic responses of individual neurons to electrical stimulation of the commissural pathway. Cells in control group typically fired in a tonic discharge mode with an average firing frequency of 2.4⁑0.9 Hz. Neuron in MK-801 treated group (0.2 mg/kg, i.p.) had an average input resistance of 32.8⁑5.7 MΩ and a membrane time constant of... -
Correlation Between Electrical Activity of Type I Neuron and c-Fos Expression in the Medial Vestibular Nuclei Following Unilateral Labyrinthectomy in Rats
ByungRimPark, NamYongDoh, MinSunKim, SangWooChun, MoonYoungLee, SungHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 5 505-513 (9 pages)
To search the correlations between electrical activity and c-Fos expression in the process of vestibular compensation, we examined the changes of those two parameters in the medial vestibular nuclei (MVN) of unilaterally labyrinthectomized (ULX) rats. Spontaneous nystagmus with fast component toward the intact side disappeared gradually within 48 hours. Fourty eight hours after ULX, directional preponderance of the eye movement induced by sinusoidal rotation of the whole body which represents... -
경두개 자기 자극(Transcranial Magnetic Stimulation)의 신경정신과적 응용
채정호, 전태연 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 1호 1 3-11 (9 pages)
연구목적： 두부 표면에서 유도시킨 국소 자기장 파동을 이용하여 두뇌 피질을 자극할 수 있도록 하는 새로운 비침습 적 시술 방법인 경두개 자기 자극(Transcranial Magnetic Stimulation：이하 TMS)은 중추 및 말초 신경계의 전도도, 시각 정보 처리, 언어, 기억, 감정 및 운동 등 다양한 두뇌 기능을 국재화하는 데에 널리 사용되고 있으며 특히 두뇌 피질을 국소적으로 자극할 수 있다는 특징으로 인해 여러 신경정신과적 질환의 새로운 치 료 방법으로도 이용될 수 있다는 가능성이 대두되고 있다. 본 논문은 TMS의 발달 과정, 기전... -
치료 저항성 환청을 호소하는 정신분열병 환자에 대한 반복 경두개 자기자극(rTMS)과 전기충격요법 (Modified ECT)의 연속적인 치료 경험 1례
권준수, 전홍진, 윤탁 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 17 734-741 (8 pages)
정신분열병에서 치료에 반응하지 않으며 지속되는 환청은 환자에게 매우 불쾌한 감정을 유발할 수 있으며 환청의 내용에 따라 위험한 경우도 있다. 환청에 대한 기능적 뇌영상 연구 결과로 환청이 정상 청각 경로의 비정상적인 활성으로 발생하며, 환청이 들리는 동안에 좌측 상부 측두엽 등이 활성화 된다는 사실을 알게 되 었다. 본 증례에서는 항정신병 약물에 대한 치료 저항성 환청을 가진 35세 기혼 여자 환자에 대해서, 좌측 상부 측두엽을 국재화한 후 뇌의 국소적 자극이 가능한 Magstim 200 장비와 Double cone shaped coil을... -
간경변증 환자의 정신과적 특성 및 아임상적 간성뇌병증 진단을 위한 연구 - 인지기능 및 유발전위를 중심으로 -
유승호, 이소영, 김진세, 변관수, 정인과 대한신경정신의학회 신경정신의학 15 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 5호 9 842-856 (15 pages)
연구목적： 본 연구는 명백한 간성뇌병증이 없는 간경변증 환자에서 불안, 우울기분 및 삶의 질 등 정신과적 특징과 신경심리학적인 결손의 양상을 밝히기 위해서 고안되었다. 그리고 아임상적 간성뇌병증의 평가에서 체성감각 유발전위 검사의 역할을 연구하고자 하였다. 방 법： 간경변증으로 진단된 41명의 환자군과 정상 대조군 31명을 대상으로 하였다. 이들에서 우울기분 및 불안 을 평가하기 위해 Beck Depression Inventory와 State & Trait Anxiety Inventory를 시행하였고 삶의 질 의 평가를 위해 Health-related Quality of... -
흡연에 의한 체성감각유발전위의 변화
대한신경정신의학회 신경정신의학 1996, 제 35권 제 4호 20 927-935 (9 pages)
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만성주정중독자의 시각유발전위반응
설석구, 김종길 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 1991, 제 30권 제 4호 8 703-709 (7 pages)
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환청이 있는 정신분열증 환자의 뇌간 청각유발전위
송정중, 김광수, 유태열 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 1991, 제 30권 제 2호 2 271-277 (7 pages)
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Effects of the Occupational Therapy Using the Music-Based Cognitive Stimulation Digital Device Program on Elderly’s Cognitive Function, Depression and Hand Function
Lee Bo-Min, Sung Yoon-Jeong, Lee Jung-Hwa, Han Eun-Young, Yang Yeong-Ae 대한고령친화산업학회 대한고령친화산업학회지 11 Pages
대한고령친화산업학회 대한고령친화산업학회지 2021, 제 13권 제 1호 1 1-11 (11 pages)
Objective : The purpose of this study is to find the influence of the occupational therapy that uses a music-based cognitive stimulation digital device on normal elderly’s cognitive function, depression and hand function. Methods : From May to July 2019, the intervention was carried out twice a week for a total of 10 sessions and 60 minutes per session for five weeks. The experimental group(n=14) participated in the occupational therapy using the music-based cognitive stimulation digital device... -
Comparison of Brain Connectivity in Mental Practice and Physical Performance of Bilateral Upper Extremity Function in a Healthy Adult: A Case Study
Jeong Eun-Hwa, Kim Hee 대한신경계작업치료학회 재활치료과학 10 Pages
대한신경계작업치료학회 재활치료과학 2019, 제 8권 1호 3 41-50 (10 pages)
Objective: The purpose of this study was to investigate whether there is a difference in the brain connectivity in mental practice and physical performance of training bilateral upper extremity function. Method: The subject performed activities involving mental tasks and physical exercise for bilateral upper extremity functioning during each phase of EEG measurements. The subject performed a symmetrical task(lifting a box and placing it back) that involved moving both arms at the same time and... -
누적 청취 음량 측정을 위한 스마트폰 어플리케이션의 개발
신지훈, 김기쁨, 한우재, 송창근 한국청각언어재활학회 Audiology and Speech Research 8 Pages
한국청각언어재활학회 Audiology and Speech Research 2017, 제 13권 제 4호 4 287-294 (8 pages)
산업 기술의 발달로 인해 현대인의 삶은 보다 편리해졌으나, 기계를 사용하는 과정에서 발생되는 과도한 소음은 청력을 손 실 시키는 등 현대인들에게 부정적인 영향을 주고 있다(Kim, 2003). 특히, 스마트폰의 광범위한 보급 및 확산으로 인해 현대 인들은 일상생활 속에서 별도의 음향기기의 구매 없이도 자체 내장된 MP3 플레이어 기능을 활용한 음악 청취 및 동영상 시청 이 용이해졌다. 그러나 음악 청취 시 일정 강도 이상의 볼륨으로 고강도의 소리에 지속적으로 노출됨에 따라 무분별한 음악 청 취는 현대인의 소음성 난청... -
이명의 요양과 장애 보상: 전역 군인의 군 소음으로 인한 이명 장애를 중심으로
김규상 한국청각언어재활학회 Audiology and Speech Research 7 Pages
한국청각언어재활학회 Audiology and Speech Research 2017, 제 13권 제 3호 2 209-215 (7 pages)
이명은 외부의 음원으로부터의 자극 없이 소리를 느끼는 상 태, 혹은 신체 내부에서 들리는 원하지 않는 청각적 자극이다. 이명은 실제 소리가 나지 않음에도 불구하고 소리가 들리는 것 을 호소하는 일종의 증상이다. 이명은 난청, 현기증과 더불어 중요한 청각 증상의 하나이다. 산업의 발달로 인한 소음 증가, 노령화 추세, 복잡한 생활과 약물남용 등 이명의 유발인자는 증 가하는 추세에 있다. 이명은 생명에 위협적이거나 다른 질병을 유발하는 위험한 장애는 아니지만, 이명으로 인해 나타나는 집 중력 장애, 수면장애, 불안 및... -
이명에 대한 심리적 측정과 심리음향학적 측정
최철희 한국청각언어재활학회 Audiology and Speech Research 12 Pages
한국청각언어재활학회 Audiology and Speech Research 2012, 제 8권 제 2호 1 137-148 (12 pages)
