자료유형
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전체 선택해제
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Reliability and validity of the patellofemoral disability index as a measure of functional performance and subjective pain in subjects with patellofemoral pain syndrome
Mastour Saeed Alshaharani, Everett Bernell Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Noha S. Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 3 61-66 (6 pages)
(ODI) at baseline after two weeks, and after four weeks. Pearson correlation coefficient was used to assess the criterion validity. Cronbach’s α was used to examine the internal consistency. Intraclass correlation coefficients with 95% confidence interval were computed to examine test-retest reliability. Results: Subjects’ responses within both the PDI and the ODI yielded Pearson correlation coefficient values that were positive and highly significant (range, 0.73-0.97; p<0.001). There was a... -
Predictive analyses for balance and gait based on trunk performance using clinical scales in persons with stroke
Young-keun Woo 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 1호 6 29-34 (6 pages)
of >45 for regression equation for predicting BBS score using TIS score, the coefficient of determination (R2) was 0.234, and the R2 was 0.500 in the group with a BBS score of ≤45. In the group with an FGA score >15 for regression equation for predicting FGA score using TIS score, the R2 was 0.193, and regression equation for predicting FGA score using TIS score, the R2 was 0.181 in the group of FGA score ≤15. In the group of FGA score >15 for regression equation for predicting FGA score using... -
The effect of single trial transcutaneous electrical nerve stimulation on balance and gait function in elderly people with dementia
Ju Yeon Jung, Jin-Hwa Jung, Suk-Chan Hahm, Kyoung-sim Jung, Sung-Jin Kim, Hye Rim Suh, Hwi-young Cho 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 2 59-64 (6 pages)
Objective: Elderly people with dementia experience not only cognitive dysfunction but also motor function deficits, such as balance and gait impairments. Recently, transcutaneous electrical nerve stimulation (TENS) has been used to reduce pain as well as to control muscle spasm, spasticity and motor performance in various types of subjects. The purpose of this study determined the effect of a single trial TENS on balance and gait function in elderly people with dementia. Design: A randomized... -
Immediate effect of self-myofascial release on hamstring flexibility
Ji-hye Jung, Won-jae Choi, Yong-hyuk Lee, Ji-woo Kim, Hyun-ju Kim, Kyoung-ho Lee, Jae-woo Lee, Seung-won Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 8 45-51 (7 pages)
Objective: This study aimed to identify the area with greatest effect using self-myofascial release technique (self-MFR) in the hamstring, suboccipital, and plantar regions. Design: Cross-sectional study. Methods: Twenty-two adult subjects were evaluated for flexibility and hamstring pain threshold after self-MFR. Based on the superficial back line, the self-MFR application areas were the suboccipital region, hamstring, and plantar regions. Self-MFR was applied to each area using a wooden pole... -
Relationship between the quality of life of the caregiver and motor function of children with cerebral palsy
Chang-Kyo Yun 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 5 26-32 (7 pages)
Objective: The purpose of this study was to evaluate the relationship between quality of life (QoL) of the caregiver and disease severity with motor function in children with cerebral palsy (CP). Design: Cross-sectional study. Methods: Research data were collected in the Rehabilitation Clinic of Daegu University. The Gross Motor Function Measure (GMFM-88) and the functional independence measure (FIM) were used for assessment by three occupational therapists, and the 36-item short form health... -
The effect of hip joint exercise using an elastic band on dynamic balance, agility and flexibility in healthy subjects
Dong Hyun Kang, Woo Hyung Lee, Song Lim, Yu Yeong Kim, Soung Wook An, Chang Gyeong Kwon, Gyeong Hee Lee, Nu Ri Choi, Na Yeong Lee, Bo Min 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 6 198-204 (7 pages)
Objective: The purpose of this study was to examine the effects of hip joint exercise using an elastic band on dynamic balance, agility, and flexibility in healthy subjects. Design: Randomized controlled trial. Methods: Thirty-five subjects (between 19 and 23 years) were randomly allocated to two groups: hip flexion exercise (HFE)group (n=17) and the hip abduction exercise (HAE) group (n=18). The HFE group participated in flexion exercise of the hip joint using an elastic band for 50 minutes a... -
Effects of sit-to-stand imagery group training on balance performance in individuals with chronic hemiparetic stroke
Jeong-won Lee, Su-jin Hwang, Sin-ae Ahn 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 2 63-69 (7 pages)
Objective: To evaluate the effects of sit-to-stand (STS) imagery group training (IGT) on STS movement and balance performance for chronic hemiparetic stroke. Design: Randomized controlled trial. Methods: A total of 30 people with chronic hemiparetic stroke (15 for STS-IGT group and 15 for control) were recruited in this study. The STS-IGT group participated in a videotape-based STS-IGT for 30 minutes a day, five days a week for six weeks, while the control group watched a documentary on... -
The comparison of muscle activity according to various conditions during smartphone use in healthy adults
You Lim Kim, Jae-hyun Yoo, Sin-woo Kang, Tae-rim Kim, Nam-yeol Kim, So-jeong Hong, Won-jeong Hwang, Suk Min Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 1호 3 15-21 (7 pages)
Objective: The purpose of this study was to see the changes in muscle activity of the upper limb in persons using a smartphone. Design: Cross-sectional study. Methods: An experiment was conducted to target 15 right-handed university students. Experiments were carried out for students using cell phones for more than a year. In this study, experiments were carried out with one-handed and both handed operation of smartphone use in a sitting position, the same parameters with smartphone use in a... -
Predictive validity of the gait scale in the Performance Oriented Mobility Assessment for stroke survivors
Seung-heon An, Young-ju Jee, Dong-geon Lee, Sun-hae Song, Gyu-chang Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 1호 1 1-8 (8 pages)
Objective: The present study was to investigate the discrimination capacity of the Performance Oriented Mobility Assessment-Gait Scale (POMA-GS), for predicting falls in stroke survivors. Design: Retrospective cohort study. Methods: Data including the characteristics and number of falls of 52 chronic stroke patients from a rehabilitation center were collected. The number of falls each subject had experienced in the previous year were investigated through interviews. The subjects were divided... -
The immediate effects of patellar taping on balance and gait ability in individuals with chronic stroke
Jin Shin, Mee-Hyang Mun, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 9 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 8 125-133 (9 pages)
Objective: The aim of this study is to investigate the effect of patellar taping on balance and gait abilities in chronic stroke patients. Design: Randomized placebo-controlled trial. Methods: Thirty chronic stroke patients who have been diagnosed at least six months or before were recruited from R hospital. These study subjects were randomized to the experimental group (n=15) or placebo group (n=15). In the experimental group, patellar taping was applied while for the placebo group, placebo... -
Wheelchair martial arts practitioners have similar bone strength, sitting balance and self-esteem to healthy individuals
Shirley S. M. Fong, Shamay S. M. Ng, Anthony O. T. Li, X. Guo 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 5 27-32 (6 pages)
Objective: The aim of this study was to compare the radial bone strength, sitting balance ability and global self-esteem of wheelchair martial arts practitioners and healthy control participants. Design: Cross-sectional study. Methods: Nine wheelchair martial art practitioners with physical disabilities and 28 able-bodied healthy individuals participated in the study. The bone strength of the distal radius was assessed using the Sunlight Mini-Omni Ultrasound Bone Sonometer; sitting balance was... -
Relationship of neck disability index, shoulder pain and disability index, and visual analogue scale in individuals with chronic neck pain
Su-jin Hwang, Mee-Hyang Mun 물리치료재활과학회 Physical Therapy Rehabilitation Science 4 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 9 111-114 (4 pages)
Objective: Several muscles surrounding neck are vital not only for neck motion, but for upper extremities motions as well. Neck pain would affect neck and shoulder disability. The Neck Disability Index (NDI), Shoulder Pain and Disability Index (SPADI), and Visual Analogue Scale (VAS) are increasingly used to evaluate treatment effectiveness after chronic neck pain. The purpose of this study was to analyze the correlation of neck pain, shoulder pain, and quality of life in patients with chronic... -
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Yiming Shen, Seong Kyu Han, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 2 483-491 (9 pages)
＜ 0.05). The PVNRVLM neurons showed smaller resting membrane potential, slower rise and decay times, and greater duration of spontaneous action potentials (p ＜ 0.05). The PVNRVLM neurons received greater inhibitory synaptic inputs (frequency, p ＜ 0.05) with a shorter rise time (p ＜ 0.05). Taken together, the results indicate that the two pre-sympathetic neurons differ in their intrinsic and extrinsic electrophysiological properties, which may explain the lower firing activity of the PVNRVLM... -
Alginate encapsulation preserves the quality and fertilizing ability of Mediterranean Italian water buffalo (Bubalus bubalis) and Holstein Friesian (Bos taurus) spermatozoa after cryopreservation
Sara Perteghella, Alessandro Gaviraghi, Silvia Cenadelli, Valeria Bornaghi, Andrea Galli, Barbara Crivelli, Barbara Vigani, Dani 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 11 81-88 (8 pages)
semen, low resistance of sperm cells in the female tract, difficulties in estrus detection, and variable estrus duration. Although AI procedures are commonly used in bovine, use of AI has been limited in buffalo. In the zootechnical field, different studies have been conducted to develop techniques for improvement of fertilizing ability of buffalo spermatozoa after AI. In this study, for the first time, the use of alginate encapsulation and cryopreservation of buffalo spermatozoa is described,... -
Quantitative CT assessment of bone mineral density in dogs with hyperadrenocorticism
Donghoon Lee, Youngjae Lee, Wooshin Choi, Jinhwa Chang, Ji-Houn Kang, Ki-Jeong Na, Dong-Woo Chang 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 18 531-542 (12 pages)
Canine hyperadrenocorticism (HAC) is one of the most common causes of general osteopenia. In this study, quantitative computed tomography (QCT) was used to compare the bone mineral densities (BMD) between 39 normal dogs and 8 dogs with HAC (6 pituitary-dependent hyperadrenocorticism [PDH]; pituitary dependent hyperadrenocorticism, 2 adrenal hyperadrenocorticism [ADH]; adrenal dependent hyperadrenocorticism) diagnosed through hormonal assay. A computed tomogaraphy scan of the 12th thoracic to 7th... -
Tissue Doppler and strain imaging of left ventricle in Beagle dogs with iatrogenic hypercortisolism
Heejin Oui, Sunghoon Jeon, Gahyun Lee, Seungjo Park, Kyoung-Oh Cho, Jihye Choi 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 14 357-365 (9 pages)
Changes in radial and longitudinal left ventricular (LV) function were investigated in beagles with iatrogenic hypercortisolism. A total of 11 normal dogs were used, and 2 mg/kg prednisone was administered per oral q12 h for 28 days to 7 out of 11 dogs to induce iatrogenic hypercortisolism. Body weight, blood pressure, conventional echocardiography and tissue Doppler imaging (TDI) of normal and iatrogenic hypercortisolism groups were conducted. The myocardial wall velocity of the LV was measured... -
Association of the time that elapsed from last vaccination with protective effectiveness against foot-and-mouth disease in small ruminants
Ehud Elnekave, Boris Even-Tov, Boris Gelman, Beni Sharir, Eyal Klement 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 11 87-92 (6 pages)
the average time that elapsed since last vaccination and the disease incidence (n = 5; Spearman correlation coefficient: rs = 1.0, p＜ 0.01). In addition, non-vaccinated lambs fed colostrum from dams vaccinated more than 2 months before parturition had a mortality rate of 33%. Administration of emergency vaccination 2 days after the occurrence of the index case was the probable reason for the rapid blocking of the FMD spread within 6 days from its onset in the pen. -
Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry
Joon-Hyeok Jeon, Hae-Won Jung, Hyo-Mi Jang, Jong-Hyun Moon, Ki-Tae Park, Hee-Chun Lee, Ha-Young Lim, Jung-Hyang Sur, By 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 10 75-85 (11 pages)
(IL)-6 with clinical prognosis was assessed. Ischemic stroke was induced by permanent middle cerebral artery occlusion (MCAO) in nine healthy experimental dogs. The dogs were divided into three groups according to survival time and duration of the experimental period: group A (survived only 1 day), group B (1-week experimental period), and group C (2-week experimental period). Neurologic status was evaluated daily. Magnetic resonance imaging (MRI) was performe... -
Assessing PCV2 antibodies in field pigs vaccinated with different porcine circovirus 2 vaccines using two commercial ELISA systems
Min-Kyoung Shin, Seung Hyun Yoon, Myung Hwui Kim, Young Soo Lyoo, Seung Won Suh, Han Sang Yoo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 4 25-29 (5 pages)
and 42 negative samples, indicating 78.7% agreement. In addition, the Pearson coefficient (0.636) indicated a moderate correlation between data from the two ELISAs. Results from the farms with pigs vaccinated with the three different PCV2 vaccines demonstrated that most of the vaccinated animals underwent seroconversion. However, the increase and duration of antibody titers varied depending on the vaccine, the presence of maternal antibodies, and the vaccination... -
C-reactive protein as an indicator of inflammatory responses to experimentally induced cystitis in dogs
Kyoung-won Seo, Jong-bok Lee, Jin-Ok Ahn, Hee-woo Lee, Cheol-yong Hwang, Hwa-young Youn*, Chang-woo Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 9 179-185 (7 pages)
The aim of this study was to demonstrate and assess C-reactive protein (CRP) changes in dogs with induced bacterial cystitis with or without antibiotics. We also evaluated availability of CRP levels to serve as an indicator for monitoring or diagnosing bacterial cystitis. Serial CRP concentrations in dogs with induced bacterial cystitis were higher than those of controls (p ＜ 0.001). CRP concentrations peaked on day 7 and gradually decreased thereafter. In the treatment group, CRP... -
Autoantibodies against thyroid hormones and their influence on thyroxine determination with chemiluminescence immunoassay in dogs
Marion Piechotta*, Michael Arndt, Hans-Otto Hoppen 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 3 191-196 (6 pages)
= 110). The incidence of T4AA and T3AA, determined using radiometric assay, was low (0.5% and 3.8%) and higher in hypothyroid dogs compared to dogs suspicious for hypothyroidism (Group 2-4) (p＜0.05). T4AA was not detected in dogs with normal T4 and elevated TSH. T4 concentrations of T4AA positive samples determined using HPLC were comparable to results obtained by chemiluminescence immunoassay. These findings indicate that the probability of interference of T4AA leading to falsely elevated T4... -
Disposition kinetics and dosage regimen of levofloxacin on concomitant administration with paracetamol in crossbred calves
Vinod K. Dumka* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 7 357-360 (4 pages)
declined to 6.39±0.16 ■g/ml at 10 min. The drug level above the MIC90 in plasma, was detected for up to 10 h. Levofloxacin was rapidly distributed from blood to the tissue compartment as evidenced by the high values of the distribution coefficient, ■ (17.3 ± 1.65 /h) and the ratio of K12/K21 (1.83 ± 0.12). The values of AUC and Vdarea were 12.7±0.12 ■g.h/ml and 0.63 ± 0.01 l/kg. The high ratio of the AUC/ MIC (126.9±1.18) obtained in this study indicated the... -
Disposition kinetics and urinary excretion of cefpirome after intravenous injection in buffalo calves
Neetu Rajput, Vinod K. Dumka, Harpal S. Sandhu 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 4 21-25 (5 pages)
the high distribution coefficient values (8.67 ± 0.46/h), and by the drug’s rate of transfer constant from the central to the peripheral compartment, K12 (4.94 ± 0.31/h). The elimination halflife and the volume of distribution were 2.14 ± 0.02 h and 0.42 ± 0.005 l/kg, respectively. Once the distribution equilibrium was reached between the tissues and plasma, the total body clearance (ClB) and the ratio of the drug present in the peripheral to the central compartment (T/P ratio) were 0.14 ±... -
Surgical treatment of spinal cord compression in client owned dogs with different grades of neurological dysfunction
Maria Kuricova , Valent Ledecky , Tomas Liptak 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 2호 9 113-116 (4 pages)
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Comparative pharmacokinetics of norfloxacin-glycine acetate after single oral administration and medication with drinking water in broilers
JongHwanLim, ByoungYongLim, ByungKwonPark, MyongSeokKim, BeomSuJang, SeungChunPark, HyoInYun 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2004, 제 44권 제 2호 7 201-206 (6 pages)
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두부방사선 분석에 의한 상악전치부 후방이동시 연조직 변화 예측에 대한 연구
최진희(Jin-Hee Choi), 이진우(Jin-Woo Lee), 차경석(Kyung-Suk Cha) 대한치과교정학회 The Korean Journal of Orthodontics 14 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 1호 6 65-78 (14 pages)
본 연구는 성장에 의한 효과를 배제한 교정치료시의 연조직 변화와 치아 및 악골의 수평적, 수직적 움직임과의 상관관계를 알아보고 예측 가능성을 검토하기 위해 Angle씨 2급 1류 부정교합 환자 41명을 대상으로 치아 및 악골, 연조직의 수평, 수직이동의 평균 변화량을 측정하고 연조직에 대한 계단식 다중 회귀분석을 시행하였으며 다음과 같은 결론을 얻었다 1. 경조직 계측항목 중 상악 중절치의 수평이동 및 기울기, 하악 중절치의 수평 및 수직이동, 수평피개량, 수직피개량, interincisal angle, 하악골 위치 변화, A, B 경조직... -
Korean Music Performance Anxiety Scale: Validation and Reliability
Su-Young Bae 한국음악교육학회 음악교육연구 21 Pages
한국음악교육학회 음악교육연구 2020, 제 49권 제 3호 2 29-49 (21 pages)
The purpose of the present study was to develop a Korean Music Performance Anxiety Scale (K-MPAS) to measure music performance anxiety of college music major students in Korea. Items were developed based on previous scales: the Music Performance Anxiety Inventory for Adolescents (MPAI-A) by Osborne & Kenny (2005) and the Personal Report of Confidence as a Speaker (PRCS) by Paul (1966). The preliminary K-MPAS comprising 26 items was conducted to 230 college music major students to verify the... -
Comparison of electrophysiological effects of calcium channel blockers on cardiac repolarization
Hyang-AeLee, Sung-AeHyun, Sung-GurlPark, Ki-SukKim, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 15 119-127 (9 pages)
of action potential duration (APD) due to the reduction of Ca2+ channel current (ICa) might increase the risk of arrhythmia. In this study we investigated the electrophysiologicaleffects of nicardipine (NIC), isradipine (ISR), and amlodipine (AML) on the cardiac APD in rabbit Purkinje fibers, voltage-gated K+ channel currents (IKr, IKs) and voltage-gated Na+ channel current (INa). The concentration-dependent inhibition of Ca2+ channel currents (ICa) was examined in rat cardiomyocytes; these CCBs... -
Blockade of Kv1.5 by paroxetine, an antidepressant drug
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 10 75-82 (8 pages)
and a Hill coefficient of 4.11 µM and 0.98, respectively. Paroxetine accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between –30 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to 0 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance d of 0.32. The binding (k+1) and unbinding (k–1) rate... -
Effect of Stimulus Waveform of Biphasic Current Pulse on Retinal Ganglion Cell Responses in Retinal Degeneration (rd1) mice
KunNoAhn, JeongYeolAhn, Jae-hyungKim, KyoungrokCho, Kyo-inKoo, SolomonS.Senok, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 12 167-175 (9 pages)
of the pulse. For intensities (or duration) modulation, duration (or amplitude) of the pulse was fixed to 500 μs (30 μA), changing the intensities (or duration) from 2 to 60 μA (60 to 1000 μs). RGCs were classified as response-positive when PSTH showed multiple (3∼4) peaks within 400 ms post stimulus and the number of spikes was at least 30% more than that for the immediate pre-stimulus 400 ms period. RGC responses were well modulated both with anodic and cathodic phase-1st biphasic pulses.... -
A Computational Model of the Temperature-dependent Changes in Firing Patterns in Aplysia Neurons
NamGyuHyun, Kwang-HoHyun, Kwang-BeomHyun, Jin-HeeHan, KyungminLee, Bong-KiunKaang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 8 371-382 (12 pages)
We performed experiments using Aplysia neurons to identify the mechanism underlying the changes in the firing patterns in response to temperature changes. When the temperature was gradually increased from 11oC to 31oC the firing patterns changed sequentially from the silent state to beating, doublets, beating-chaos, bursting-chaos, square-wave bursting, and bursting-oscillation patterns. When the temperature was decreased over the same temperature range, these sequential changes in the firing... -
Response of IKr and hERG Currents to the Antipsychotics Tiapride and Sulpiride
Su-HyunJo, So-YoungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 9 305-310 (6 pages)
The human ether-a-go-go-related gene (hERG) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of two antipsychotics, tiapride and sulpiride, on hERG channels expressed in Xenopus oocytes and also on delayed rectifier K＋ currents in guinea pig cardiomyocytes. Neither the amplitude of the hERG outward currents measured at the end of the voltage pulse, nor the amplitude of hERG tail currents, showed any... -
Effect of Defibrotide on Rat Reflux Esophagitis
HyoungKiKim, SooRanChoi, SangJinChoi, MyungSupChio, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 5 319-328 (10 pages)
This study was aimed at evaluating the effect of defibrotide on the development of the surgically induced reflux esophagitis, on gastric secretion, lipid peroxidation, polymorphonuclear leukocytes (PMNs) accumulation, polymorphonuclear leukocytes adherence, superoxide anion and hydrogen peroxide production in PMNs, scavenge of hydroxyl radical and hydrogen peroxide, cytokine (interleukin-1β, tumor necrosis factor-α) production in blood, and intracellular calcium mobilization in PMNs.... -
Effect of Capsaicin on Delayed Rectifier K+ Current in Adult Rat Dorsal Root Ganglion Neurons
JunghyunHahn, SungkwonChung, HyoweonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 2 9-14 (6 pages)
K currents play multiple roles in the excitability of dorsal root ganglion (DRG) neurons. Influences on these currents change the shape of the action potential, its firing threshold and the resting membrane potential. In this study, whole cell configuration of patch clamp technique had been applied to record the blocking effect of capsaicin, a lipophilic alkaloid, on the delayed rectifier K current in cultured small diameter DRG neurons of adult rat. Capsaicin reduced the... -
Effects of Cl Channel Blockers on the Cardiac ATP-sensitive K+ Channel
Yong-GeunKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 8 305-313 (9 pages)
To explore whether Cl channel blockers interact with the ATP-sensitive K (KATP) channel, I have examined the effect of two common Cl channel blockers on the KATP channel activity in isolated rat ventricular myocytes using patch clamp techniques. In inside-out patches, 4,4'-diisothio-cyanatostilbene- 2,2'-disulfonic acid (DIDS) and niflumic acid applied to bath solution inhibited the KATP channel activity in a concentration-dependent manner with IC50 of 0.24 and 927μM,... -
Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery
TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)
and inactivation of IK(V) was at the more hyperpolarized range than that of Ito contrary to the reports in other vascular SMCs. Tetraethylammonium chloride (TEA; 10 mM) markedly inhibited IK(V) but little affected Ito. 4-Aminopyridine (4-AP) had similar inhibitory potency on both currents. While a low concentration of Cd2+ (0.5 mM) shifted the current- voltage relationship of Ito to the positive direction without change of maximum conductance, Cd2+ did not cause any appreciable change for IK(V). -
酒精依存에서 性機能障碍의 機轉：外陰部神經 感覺誘發電位(Pudendal SEP) 硏究
대한신경정신의학회 신경정신의학 1997, 제 36권 제 1호 13 135-144 (10 pages)
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항정신병 약물 비복용 정신분열증 환자의 99m-Tc-ECD SPECT로 측정한 국소뇌혈류량과 증상과의 관계
안석균, 전덕인, 이종두, 민성길 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 1997, 제 36권 제 3호 3 433-443 (11 pages)
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정신분열증 환자의 인지재활을 위한 사회지각척도의 개발
안석균, 손석한, 이만홍, 이희상, 안혜리 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 1998, 제 37권 제 2호 7 261-272 (12 pages)
연구목적： 저자들은 정신분열증 환자군 및 정상인을 대상으로 하여 Brenner등의 인지재활전략에 합당하며, 시각지각 과 분위기지각으로 세분화하여 사회지각 결핍을 발견할 수 있고, 바람직한 신뢰도 및 변별력을 갖춘 사회지 각척도를 개발하고자 본 연구를 수행하였다. 방 법： 저자들은 다양한 사회적 상황을 나타내는 사진 30장 중에서 통합심리치료연구팀의 구성원들의 의견 일치 에 따라서 10장의 사진을 선정하였다. 그런 다음에 저자들은 시각지각 소척도와 분위기지각 소척도로 이루 어진 문항을 개발하였고 이를 사회지각척도... -
정신분열병 환자의 병식과 정신병리
정두훈, 송지영, 염태호, 윤도준, 반건호, 김종우 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 1998, 제 37권 제 6호 1 1013-1022 (10 pages)
연구목적： 정신분열병 환자에서 병식의 결여는 매우 흔한 증상이며, 치료 예후에 큰 영향을 미치는 바, 정신분열병 환자의 병식결여가 어떠한 정신병리적 특성이 있는지를 규명하고자 하였다. 이로서 병식결여환자에 대한 이 해와 치료적 접근에 기여하고자 한다. 방 법： 연구대상은 DSM-Ⅳ에 의거한 정신분열병 환자 69명으로서, 이들에게 병식 평가검사척도(Scale to Assess Unawareness of Mental Disorder)와 다양한 정신병리적 측면을 측정할 수 있는 경희-프랑크푸르 트(Kyung Hee-Frankfurter Beschwerde Fragebogen；K-FBF)... -
항정신병 약물치료하에서 주관적 안녕감을 평가하는 한국형 척도의 개발
윤진상, 국승희, 이형영, 이철, 백인호 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 6호 2 987-998 (12 pages)
연구목적： 본 연구의 목적은 1994년 Naber등이 개발한 38문항의‘항정신병 약물치료하에서 주관적 안녕감을 평가 하는 자가평정척도(a self-rating scale to measure subjective well-being under neuroleptic treatment： SWN)’를 문항수를 줄이고 문항내용을 수정하여 한국형으로 개발하고자 하였다. 방 법： 204명의 정신분열병 환자들에게 22문항의 KmSWN과 General Health Questionnaire/Quality of Life- 12(GHQ/QL-12)를 실시하였고, 사회인구학적 및 임상적 특징을 조사하였다. 자료분석에는 척도에 대한 반 응과 정보가... -
정신분열병 입원 환자에서 단축형 증상관리 훈련의 효과：예비적 연구
최충식, 채정호, 우동원, 최영희, 함웅, 이규항, 장미화 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 1호 7 72-80 (9 pages)
연구목적： 정신분열병 환자에서의 재활치료는 개인의 극복 기술과 능력을 향상시키고 재발을 유발시킬 수 있는 스트 레스의 부정적인 영향을 중화시킴으로써 질병의 만성화를 막고 사회기능을 호전시킬 수 있기에 점차 그 중 요성이 대두되고 있다. 본 연구는 만성 정신분열병 입원 환자에서 재활치료의 하나인 단축형 증상관리 훈련 이 정신장애에 대한 자기 인식에 미치는 효능을 알아보기 위하여 시행되었다. 방 법： 정신분열병으로 진단받고 입원 중인 환자들에게 재발경고징후를 규명하는 것, 재발경고징후를 관리하는 것,... -
만성 남자 정신분열병 환자의 병식 정도와 기질 및 성격 유형과의 관계
강여화, 김봉조, 손진욱 대한신경정신의학회 신경정신의학 15 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 5호 15 908-922 (15 pages)
연구목적： 남자 만성 정신분열병 입원 환자에서의 병식 정도와 기질 및 성격유형간의 관련성을 규명하고자 한다. 부 가적으로 병식 정도에 따른 사회 인구학적 변인 및 질병 연관 변인의 차이를 알아보고자 한다. 연구방법： 병식 평가를 위해 McEvoy등이 고안한‘병식과 치료태도에 대한 설문(ITAQ：Insight and Treatment Attitudes Questionnaire)’과 Amador 등이 고안한 병식 평가 검사(SUMD：Scale to Assess Unawareness of Mental Disorder)를 이용한 구조화된 면담을 시행하였다. 다음, Cloninger의 기질-성격 척도(TCI：... -
정신분열병 환자의 삶의 질과 정신병리： 주관 및 객관적 평가
서호석, 김찬형, 이홍식, 정영철, 최영희, 허시영, 이철 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 11 1122-1131 (10 pages)
연구목적： 삶의 질은 정신분열병의 치료에서 임상 결과의 다원적인 평가, 재활 프로그램의 평가 등과 함께 최근 개발되 고 있는 새로운 항정신병 약물의 임상 평가에 중요하다. 이전 연구에서 삶의 질에 대한 평가는 주관적 평가 및 객관적 평가 단독으로 각각 시행되어지긴 했으나, 함께 평가된 연구나 이들의 관련성에 대한 연구는 별로 없다. 본 연구에서는 정신분열병 환자의 자기 평정이 의미 있고 신뢰적인지 알아보기 위하여 삶의 질에 대한 주관적인 평가와 객관적인 평가 사이에 어떤 상관관계가 있는지를 밝혀 보고, 또한 삶의... -
한국판 양성 및 음성증후군 척도(Positive and Negative Syndrome Scale)의 신뢰도와 타당도
이중서, 안용민, 신현균, 안석균, 주연호, 김승현, 윤도준, 조경형, 구영진, 이지연, 조인희, 박영환, 김광수, 김용식 대한신경정신의학회 신경정신의학 16 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 8 1090-1105 (16 pages)
연구목적： 본 연구는 양성 및 음성 증후군 척도(Positive and Negative Syndrome Scale, PANSS)를 국어로 번역하여 우리 나라 환자들을 대상으로 신뢰도와 타당도를 검토함으로써 한국판 PANSS를 개발하는데 그 목적을 두 었다. 방 법： 11개 병원에서 DSM-Ⅳ를 기준으로 정신분열병 또는 정신분열형장애로 진단받고 입원 또는 외래 치료 중인 환자 101명을 대상으로 PANSS 평가를 실시하였다. 이중 38명에 대해서는 준거타당도를 확인하기 위 해 Scale for the Assessment of Positive Symptoms(SAPS)와 Scale for the Assessment of... -
스트레스 반응 척도의 수정판 개발 및 타당화 연구：근로자 대상
최승미, 강태영, 우종민 대한신경정신의학회 신경정신의학 13 Pages
대한신경정신의학회 신경정신의학 2006, 제 45권 제 6호 8 541-553 (13 pages)
