자료유형
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간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(21)
- JOURNAL OF VETERINARY SCIENCE(12)
- THE KOREAN JOURNAL OF ORTHODONTICS(11)
- CARBON LETTERS(9)
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- 대한약리학잡지(3)
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- 대한생리학회지(2)
- 은행법연구(2)
- 한국초전도-저온공학회논문지(2)
- ASIA-PACIFIC JOURNAL OF RESEARCH IN EARLY CHILDHOOD EDUCATION(1)
- JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY(1)
- PHYSICAL THERAPY REHABILITATION SCIENCE(1)
- SMART STRUCTURES AND SYSTEMS(1)
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- 대한건축학회논문집 : JOURNAL OF THE ARCHITECTURAL INSTITUTE OF KOREA : STRUCTURE & CONSTRUCTION / 구조계(1)
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- 정보처리학회논문지. THE KIPS TRANSACTIONS. PART A. PART A(1)
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전체 선택해제
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Effects of hand grip strength on shoulder muscle activity in breast cancer patients
Tae-Won Yun, Byoung-Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 7 95-100 (6 pages)
Objective: The purpose of this study was to investigate effects of hand grip strength on the muscle activation of shoulder joint in breast cancer patients. Design: Cross-sectional study. Methods: Ten breast cancer patients who agreed to active participation were included. These patients were operated with either conservative surgery or segmental mastectomy, and then were treated with radiation therapy and chemotherapy. The activity of the upper trapezius, lower trapezius, supraspinatus and... -
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Yiming Shen, Seong Kyu Han, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 2 483-491 (9 pages)
The hypothalamic paraventricular nucleus (PVN) contains two types of neurons projecting to either the rostral ventrolateral medulla (PVNRVLM) or the intermediolateral horn (IML) of the spinal cord (PVNIML). These two neuron groups are intermingled in the same subdivisions of the PVN and differentially regulate sympathetic outflow. However, electrophysiological evidence supporting such functional differences is largely lacking. Herein, we compared the electrophysiological properties of these... -
Comparison of three skin-stretching devices for closing skin defects on the limbs of dogs
Vassiliki Tsioli, Lysimachos G. Papazoglou, Nikolaos Papaioannou, Dimitra Psalla, Ioannis Savvas, Leonidas Pavlidis, Ma 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 13 99-106 (8 pages)
Our objective was to evaluate the effectiveness of skin-stretching devices for closing defects on the extremities of dogs. Antebrachial skin defects were created on the limbs of 24 dogs randomly divided into three groups. Skin stretchers included staples and sutures passing through them (group A), sutures and hypodermic needles (group B), and Pavletic device (group C). Wounds on the left were further undermined in all groups. Tension and blood perfusion were assessed.... -
Molecular characterization of duck enteritis virus CHv strain UL49.5 protein and its colocalization with glycoprotein M
Meng Lin, Renyong Jia*, Mingshu Wang, Xinghong Gao, Dekang Zhu, Shun Chen, Mafeng Liu, Zhongqiong Yin, Yin Wang, Xiaoyue Chen, A 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 7 389-398 (10 pages)
The UL49.5 gene of most herpesviruses is conserved and encodes glycoprotein N. However, the UL49.5 protein of duck enteritis virus (DEV) (pUL49.5) has not been reported. In the current study, the DEV pUL49.5 gene was first subjected to molecular characterization. To verify the predicted intracellular localization of gene expression, the recombinant plasmid pEGFP-C1/pUL49.5 was constructed and used to transfect duck embryo fibroblasts. Next, the recombinant plasmid pDsRed1-N1/ glycoprotein M (gM)... -
Mitochondrial and DNA damage in bovine somatic cell nuclear transfer embryos
In-Sun Hwang, Hyo-Kyung Bae, Hee-Tae Cheong 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 1 235-240 (6 pages)
＜ 0.05). The mitochondria morphology of SCNT embryos was diffused within the cytoplasm. The ΔΨ of SCNT embryos was significantly lower (p ＜ 0.05) than that of IVF embryos (0.95 ± 0.04 vs. 1.21 ± 0.06, red/green). Moreover, the comet tail length of SCNT embryos was longer than that of IVF embryos (515.5 ± 26.4 μm vs. 425.6 ± 25.0 μm, p ＜ 0.05). These results indicate that mitochondrial and DNA damage increased in bovine SCNT embryos, which may have been induced by increased ROS levels. -
The effect of melanocortin (Mc3 and Mc4) antagonists on serotonin-induced food and water intake of broiler cockerels
Morteza Zendehdel*, Farshid Hamidi, Vahab Babapour, Kasra Mokhtarpouriani, Ramin Mazaheri Nezhad Fard 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 3 229-234 (6 pages)
The current study was designed to examine the effects of intracerebroventricular injections of SHU9119 [a nonselective melanocortin receptor (McR) antagonist] and MCL0020 (a selective McR antagonist) on the serotonin-induced eating and drinking responses of broiler cockerels deprived of food for 24 h (FD24). For Experiment 1, the chickens were intracerebroventricularly injected with 2.5, 5, and 10 mg serotonin. In Experiment 2, the chickens received 2 nmol SHU9119 before being injected with 10... -
Comparison of bare metal stent and paclitaxel-eluting stent using a novel rat aorta stent model
Jin Sook Kwon, Rho Kwan Park, Tae Jin Shim, Myung Ho Jeong, Myeong Chan Cho, Youngkeun Ahn, Dong-Woon Kim 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 6 143-150 (8 pages)
The purpose of our study was to create a novel rat aorta stent implantation model. Stainless steel bare metal stents (BMS) or paclitaxel-eluting stents (PES) were implanted in male Sprague-Dawley rats (BW 400 ± 20 g). Two and four weeks after stent implantation, the aorta were collected, fixed with 2% glutaraldehyde, and cut into two segments. One segment was used for scanning electron microscopy analysis to evaluate re-endothelialization, and the other segment was used to calculate the... -
Organotypic slice culture of the hypothalamic paraventricular nucleus of rat
Eun Seong Cho, So Yeong Lee, Jae-Yong Park, Seong-Geun Hong, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 3 15-20 (6 pages)
Organotypic slice cultures have been developed as an alternative to acute brain slices because the neuronal viability and synaptic connectivity in these cultures can be preserved well for a prolonged period of time. This study evaluated a stationary organotypic slice culture developed for the hypothalamic paraventricular nucleus (PVN) of rat. The results showed that the slice cultures maintain the typical shape of the nucleus, the immunocytochemical signals for oxytocin, vasopressin, and... -
Comparative analysis of heart functions in micropigs and conventional pigs using echocardiography and radiography
Min Young Lee, Sang Hun Lee, Seung Gon Lee, Soo Hyun Park, Chai Yong Lee, Kye Hun Kim, Sun Ho Hwang, Sang Yub Lim, Young Keun Ah 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 2 7-14 (8 pages)
The production of miniature animals has been suggested for use in organ transplantation. At present, many of the studies about application of animal organs to human have been focused on pigs because of the number of advantages involved and due to their similarities with human. However, a physiological analysis of the organs to be transplanted has not yet been carried out. Therefore, this study analyzed whether or not there were physiological and morphological differences in the hearts of... -
Application of a temporary palatal prosthesis in a puppy suffering from cleft palate
Jae-il Lee, Young-suk Kim, Myung-Jin Kim, Jieun Lee, Jong-hyup Choi, Dong-bok Yeom, Jung-mi Park, Sung-Hyeok Hong 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 1호 19 93-95 (3 pages)
A 3-month-old Schnauzer was presented with congenital defects of the secondary palate.On the clinical examination, coughing, sneezing, drainage of nasal discharge from the external nares and poor growth were found.Vital signs and results of blood examination were within normal ranges.Thoracic radiography revealed mild pneumonia in the right lung lobes.In a puppy suffering from cleft palates, a palatal prosthesis was applied to the hard palate in order to protect the surgical wound, because a... -
Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat
Jeoung-Woo Kang, Tae-Wan Kim, Jun-Ho La, Tae-Sik Sung, Hyun-Ju Kim, Young-Bae Kwon, Jeum-Yong Kim, Il-Suk Yang 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 3호 2 189-195 (7 pages)
The effect of electroacupuncture (EA) on experimental colitis was investigated in Sprague-Dawley rats. Colitis was induced by intracolonic instillation of 4% acetic acid. EA (2 Hz, 0.05 ms, 2 V for 20 min) was applied to bilateral Hoku (LI-4) and Zusanli (ST-36) on 12 hrs and 36 hrs after induction of colitis. EA-treatment significantly reduced the macroscopic damage and the myeloperoxidase activity of colonic samples at 3 days post-induction of colitis. Colitic colon showed a decreased in vitro... -
Mechanism of UV light-induced photorelaxation in isolated rat aorta
Joo-heon Kim, Yonggeun Hong, Cheol-soo Shim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 2호 4 81-86 (6 pages)
long wave length UV-light. The aim of the present study was to characterize the mechanism of UV-light induced by photorelaxation in the rat aorta. 1. UV light relaxed both endothelium-intact and -denuded rat aortic rings contracted by phenylephrine. The magnitude of relaxation on UV light was dependent on the exposure time and slightly greatly in endothelium-denuded rings than in endothelium-intact preparations. 2. L-NAME (10 nM-100 uM) but not D-NAME completely inhibited the photorelaxation in... -
Establishment of normal reference of radiological morphology of renal artery in mini-pigs by renal angiography
Won Jae Lee , Ji Yeon Kim , Jae Hyung Park , Lisa Soyeon Park , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 3호 7 177-181 (5 pages)
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Intrahepatic portosystemic shunt with a second degree atrioventricular block fixed by transvenous coil embolization in a dog
Seung Gon Lee , So Jeong Nam , Hyun Wook Kim , Chang Baig Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2008, 제 48권 제 4호 15 493-500 (8 pages)
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Effects of continuous force application for extrusive tipping movement on periapical root resorption in the rat mandibular first molar
Yoshiro Matsumoto, Siripen Sringkarnboriboon, Takashi Ono 대한치과교정학회 The Korean Journal of Orthodontics 7 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 8 339-345 (7 pages)
as a non-treated control group to examine the body effect of the appliance. Active root resorption lacunae, identified using tartrate-resistant acid phosphatase, were evaluated in terms of the length, depth, and area. Results: The rat mandibular first molars were mesially tipped and extruded in the occlusal direction. This mesio-occlusal tipping movement and occlusion resulted in the formation of a compression zone and active root resorption lacunae in the distoapical third of the distal roots.... -
Displacement and stress distribution of the maxillofacial complex during maxillary protraction using palatal plates
Jusuk Eom, Mohamed Bayome, Jae Hyun Park, Hee Jin Lim, Yoon-Ah Kook, Seong Ho Han 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 4 304-315 (12 pages)
Objective: The purpose of this study was to analyze initial displacement and stress distribution of the maxillofacial complex during dentoskeletal maxillary protraction with various appliance designs placed on the palatal region by using three-dimensional finite element analysis. Methods: Six models of maxillary protraction were developed: conventional facemask (Type A), facemask with dentoskeletal hybrid anchorage (Type B), facemask with a palatal plate (Type C), intraoral traction using a... -
골격성 III급 부정교합자의 편악수술과 양악수술후 재발경향에 관한 비교연구
김정록(Jeong-Rog Kim), 손우성(Woo-Sung Son) 대한치과교정학회 The Korean Journal of Orthodontics 13 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 5호 10 613-625 (13 pages)
본 연구는 골격성 III급 부정교합 환자에서 술전 상태와 수술방법 사이의 관계 및 악교정 수술후 재발경향을 조사하기 위하여 시행하였다. 연구 대상으로는 악교정수술을 받은 31명(남자 17명, 여자 14명)을 선택하였고, 이중 20명은 편악수술, 11명은 양악 수술을 시행하였으며, 평균연령은 22.5세였다. 각 대상에서 술전, 수술직후, 1년 이상 경과 후의 측모두부방사선 규격사진을 채득하여, 투사도를 작성하고, 분석하여 다음과 같은 결과를 얻었다. 1. 하악만을 수술한 군보다 양악 동시수술군에서 하악체의 길이가 4.24mm, 하안모... -
청소년 석고 모형 분석에 의한 하악절치 형태와 치아밀집의 상관관계에 관한 연구
서정은(Jeong-Eun Surh), 백형선(Hyoung-Seon Balk) 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 5호 8 593-604 (12 pages)
discrepancy, 치관 근원심 폭경 총화와는 순상관 관계를, 하악 견치간 폭경과 제 1 소구치간 폭경과는 역상관관계를 나타내었다. 3. 상하악의 arch length discrepancy는 하악 절치의 근원심 폭경, overbite과 유의성있는 상관관계를 나타내었고 순설측 폭경과는 상관관계가 나타나지 않았다. 하악의 arch length discrepancy는 하악 절치의 MD/FL index와, 상악의 arch length discrepancy는 측절치의 MD/FL index에서 상관관계를 나타내었다. 4. 정상군과 밀집군의 각 계측항목의 t-검정 결과 하악의 arch length discrepancy,... -
Report on a case treated with lingual multibracket appliance
Hee-Moon Kyung 대한치과교정학회 The Korean Journal of Orthodontics 11 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 6호 6 705-715 (11 pages)
The lingual multibracket appliance was developed to overcome the unesthetic nature of traditional fixed orthodontic labial appliances; however, treatment with this appliance was regarded as very difficult as well as a time-consuming. Recently, these problems have been reduced because of advances in lingual bracket systems, improved indirect bonding technique and the development of more flexible wires. There has been a marked increase in the number of adults desiring orthodontic treatment over... -
A comparative study of the angles between crown axis and root axis in mesiodistal direction by using orthopantomogram
Young-Joon Kim, Hyun-Sil Choi 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 6호 2 657-666 (10 pages)
Orthopantomogram is commonly used to evaluate root parallelism. “Good parallelism” between roots is widely accepted as one of the guidelines of a successful orthodontic treatment. In case there was a large angle between crown axis and root axis, and if we valued only the position of crown in establishing occlusal relationship without considering of the situation of root, the problem of root arrangement between adjacent teeth would be occurred. The estimate of root parallelism in mesiodistal... -
FACE MAS의 치료 효과에 대한 후향적 고찰
김태우(Tae-Woo Kim), 장영일(Young-Il Chang), 남동석(Dong-Seok Nahm) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 5호 7 547-556 (10 pages)
본 연구는 성장기의 골격성 III급 부정교합 환자에서 face mask를 이용하여 상악골을 전방 견인하였을 때, 골격 및 치아관계와 연조직 측모의 변화를 관찰하고 face mask 사용전후의 경조직과 연조직 변화의 유의성을 검정하여 상악골 열성장을 보이는 골격성 III급 부정교합 환자의 진단과 치료계획 수입에 도움을 주고자 하였다. 서울대학교병원 치과진료부 교정과에 내원하여 상악골 열성장에 의한 골격성 III급 부정교합으로 진단받고 face mask를 사용하여 양호한 치료결과를 보인 환자 15명을 대상으로 face mask 사용전후 두부... -
한국인 6-17세 아동의 성장과 발육에 관한 준종단적 연구
황충주(Chung-Ju Hwang), 길재경(Jea-Kyoung Kil), 임선아(Seon-A Lim) 대한치과교정학회 The Korean Journal of Orthodontics 17 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 5호 1 469-485 (17 pages)
교정 환자들은 성장과 발육을 하는 개체이므로 교정치료의 시기 선택은 가장 어렵고 중요한 요소이며, 측모두부방사선 사진의 개발에 따라 안면 성장의 양상과 연령 증가에 따른 성장 변화량은 성장 예측 등의 교정적 분야에 유용하게 이용되어왔다. 이에 6세에서 17세까지의 한국인 남녀 아동 각 연령군에서의 두개 안면부의 경조직 계측치 평균과 신장, 체중과의 연관성을 파악하고자 하였다. 교정치룔르 받은 적이 없고, 성장과 발육에 장애가 없는 6세에서 17세까지의 소년 409명, 소녀 437명을 연구대상으로 만 3년간 두부방사선... -
상악 전치부 견인시 치근 흡수 발생 양상에 관한 연구
기세호(Se-Ho Kee), 이진우(Jin-Woo Lee), 차경석(Kyung-Suk Cha) 대한치과교정학회 The Korean Journal of Orthodontics 7 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 4호 10 441-447 (7 pages)
본 연구는 상악 전돌증을 보이는 환자에게서 상악 제1소구치를 발치한 후 견인시 bracket 종류에 따른 치근흡수 차이, 이동양상에 따른 치근 흡수 차이, 각 치아간에 따른 전치부의 치근 흡수 정도를 연구하기 위해 단국 대학교 부속 치과 병원 교정과에 내원한 남녀 환자 32명을 대상으로 연구하여 다음과 같은 결과를 얻었다. 1. 상악 전치 후방 견인시 치근 흡수를 보이지 않는 것은 31.77%, 약간의 흡수는 33.33%, 치근의 1/4이하 흡수는 23.96%, 1/4이상은 10.94%를 보였다. 2. Apical tipping, lingually bodily movement, ant-post... -
3차원 두부방사선규격사진의 정확성에 관한 연구
배기선(Gi-Sun BAE), 박수병(Soo-Byung Park), 손우성(Woo-Sung Son) 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 1호 11 129-140 (12 pages)
본 연구는 교정 임상에서 흔히 촬영되는 측모와 정모 두부방사선규격사진을 사용하여 3차원적인 두개안면 형태를 재현하였을 때 그 방법의 정확성을 고찰해 보고, 기존의 측모 두부방사선규격사진과 비교하여 어떠한 차이를 보이는지 알아보고자 하였다. 이를 위해 두개안면 골격모형의 3차원 두부방사선규격사진을 형성하고, 선계측과 각도 계측을 시행하였다. 여기서 얻어진 계측치들을 실제 계측치 및 측모 두부방사선규격사진에서의 계측치와 비교하여 다음과 같은 결론을 얻었다. 1. 3차원 두부방사선규격사진의 선 계측 평균 오차는... -
성인 Cleidocranial Dysplasia 환자의 교정치료: 증례보고
이수현, 백승학, 성상진 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2019, 제 22권 1호 8 45-51 (7 pages)
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선천성 구순구개열 환자의 장기적인 교정 치료 및 음성언어학적 고찰
홍지숙, 김윤지, 황용인, 김대성, 박양호 대한구순구개열학회 대한구순구개열학회지 13 Pages
대한구순구개열학회 대한구순구개열학회지 2009, 제 12권 1호 2 7-19 (13 pages)
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MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation
SeongmiLee, SeungTackOh, HaJinJeong, SokCheonPak, Hi-JoonPark, JongpilKim, Hyun-seokCho, SongheeJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 7 625-632 (8 pages)
Familial Parkinson’s disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this study, we developed a new PD model in the transgenic mice expressing mutant hemizygous (hemi) or homozygous (homo) A53T α-synuclein (α-syn Tg) and their wildtype (WT) littermates by treatment with sub-toxic (10 mg/kg, i.p., daily for 5 days) or toxic (30 mg/kg, i.p., daily for 5... -
Facilitation of serotonin-induced contraction of rat mesenteric artery by ketamine
SangWoongPark, HyunJuNoh, JungMinKim, BokyungKim, Sung-IlCho, YoonSooKim, NamSikWoo, SungHunKim, YoungMinBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 6 605-611 (7 pages)
Ketamine is an anesthetic with hypertensive effects, which make it useful for patients at risk of shock. However, previous ex vivo studies reported vasodilatory actions of ketamine in isolated arteries. In this study, we reexamined the effects of ketamine on arterial tones in the presence and absence of physiological concentrations of 5-hydroxytryptamine (5-HT) and norepinephrine (NE) by measuring the isometric tension of endothelium-denuded rat mesenteric arterial rings. Ketamine little... -
Dexmedetomidine inhibits vasoconstriction via activation of endothelial nitric oxide synthase
LidanNong, JueMa, GuangyanZhang, ChunyuDeng, SongsongMao, HaifengLi, JianxiuCui 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 1 441-447 (7 pages)
Despite the complex vascular effects of dexmedetomidine (DEX), its actions on human pulmonary resistance arteries remain unknown. The present study tested the hypothesis that DEX inhibits vascular tension in human pulmonary arteries through the endothelial nitric oxide synthase (eNOS) mediated production of nitric oxide (NO). Pulmonary artery segments were obtained from 62 patients who underwent lung resection. The direct effects of DEX on human pulmonary artery tension and changes in vascular... -
Extremely Low Frequency Magnetic Field Modulates the Level of Neurotransmitters
YoonHeeChung, YoungJooLee, HoSungLee, SuJinChung, CheolHeeLim, KeonWoongOh, UyDongSohn, EonSubPark, JiHoonJeong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 3 15-20 (6 pages)
This study was aimed to observe that extremely low frequency magnetic field (ELF-MF) may be relevant to changes of major neurotransmitters in rat brain. After the exposure to ELF-MF (60 Hz, 2.0 mT) for 2 or 5 days, we measured the levels of biogenic amines and their metabolites, amino acid neurotransmitters and nitric oxide (NO) in the cortex, striatum, thalamus, cerebellum and hippo-campus. The exposure of ELF-MF for 2 or 5 days produced significant differences in norepinephrine and vanillyl... -
Streptozotocin Diabetes Attenuates the Effects of Nondepolarizing Neuromuscular Relaxants on Rat Muscles
LinaHuang, DanChen, ShitongLi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 3 461-468 (8 pages)
The hypothesis of this study was that diabetes-induced desensitization of rat soleus (SOL) and extensor digitorum longus (EDL) to non-depolarizing muscle relaxants (NDMRs) depends on the stage of diabetes and on the kind of NDMRs. We tested the different magnitude of resistance to vecuronium, cisatracurium, and rocuronium at different stages of streptozotocin (STZ)-induced diabetes by the EDL sciatic nerve-muscle preparations, and the SOL sciatic nerve-muscle preparations from rats after 4 and... -
Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats
JiSeonSon, YoungBaeKwon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 2 359-364 (6 pages)
Many therapeutic roles have been proposed for sigma-1 receptor (Sig-1R), but the involvement of Sig-1R in neuropathic pain has currently not been well explored. The present study aimed to evaluate the anti-nociceptive effect of Sig-1R antagonist (BD1047) in a rat model of chronic compression of the dorsal root ganglion (CCD), which is a model of human foraminal stenosis and radicular pain. When stainless steel rods were inserted into the intervertebral foramen of lumbar vertebrae 4 and 5, the... -
P2X and P2Y Receptors Mediate Contraction Induced by Electrical Field Stimulation in Feline Esophageal Smooth Muscle
YoungRaeCho, HyeonSoonJang, WonKim, SunYoungPark, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 10 311-316 (6 pages)
It is well-known that electrical field stimulation (EFS)-induced contraction is mediated by a cholinergic mechanism and other neurotransmitters. NO, ATP, calcitonin gene-related peptide (CGRP), and substance P are released by EFS. To investigate the purinergic mechanism involved in the EFS-induced contraction, purinegic receptors antagonists were used. Suramine, a non-selective P2 receptor antagonist, reduced the contraction induced by EFS. NF023 (10−7∼10−4 M), a selective P2X... -
Are Spinal GABAergic Elements Related to the Manifestation of Neuropathic Pain in Rat?
JaeheeLee, SeungKeunBack, EunJeongLim, GyuChongCho, MyungAhKim, HeeJinKim, MinHeeLee, HeungSikNa 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 1 59-69 (11 pages)
Impairment in spinal inhibition caused by quantitative alteration of GABAergic elements following peripheral nerve injury has been postulated to mediate neuropathic pain. In the present study, we tested whether neuropathic pain could be induced or reversed by pharmacologically modulating spinal GABAergic activity, and whether quantitative alteration of spinal GABAergic elements after peripheral nerve injury was related to the impairment of GABAergic inhibition or neuropathic pain. To these aims,... -
YKP1447, A Novel Potential Atypical Antipsychotic Agent
SeonMinDong, YongGilKim, JoonHeo, MiKyungJi, JeongWooCho, ByongSungKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 1 71-78 (8 pages)
(S)-Carbamic acid 2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-1-phenyl-ethyl ester hydrochloride (YKP1447) is a novel "atypical" antipsychotic drug which selectively binds to serotonin (5-HT2A, Ki=0.61 nM, 5-HT2C, Ki=20.7 nM) and dopamine (D2, Ki=45.9 nM, D3, Ki=42.1 nM) receptors with over 10∼100-fold selectivity over the various receptors which exist in the brain. In the behavioral studies using mice, YKP1447 antagonized the apomorphine-induced cage climbing (ED50=0.93 mg/kg) and DOI-induced head... -
Nitric Oxide (NO) Inhibites the Neuronal Activities in the Rat Nucleus Tractus Solitarius
MiWonKim, MunSungPark, SunYoulRyu, JiYeonJung, YeonJinJeong, Sun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 2 7-15 (9 pages)
Nitric oxide (NO) system has been implicated in a wide range of physiological functions in the nervous system. However, the roleof NO in regulating the neural activity in the gustatory zone of nucleus tractus solitarius (NTS) has not been established. The present study was aimed to investigate the role of NO in the gustatory NTS neurons. Sprague-Dawley rats, weighing about 50 g, were used. Whole cell patch recording and immunohistochemistry were done to determine the electrophysiological... -
Neuroprotective Effect of 8-OH-DPAT on Long-term Sequelae from Prenatal Ischemia in Rats
SeoulLee, TieYuanZhang, GunTaeKim, HeeSooKim, JongDooLee, JeongWonJahng, DongGooKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 3 293-297 (5 pages)
The role of 5-hydroxytryptamine (5-HT)1A receptor activity in prenatal ischemia was studied, by injecting 8-hydroxy-dipropylaminotetraline (8-OH-DPAT; 50μg/kg, s.c.), a 5-HT1A agonist on gestation day 17, and 30 min later inducing transient ischemia by ligating the uterine vessels for 30 min. On postnatal day 95, rats that had experienced prenatal ischemia showed impaired motor coordination and reduced concentration of 5-HT in the cerebellum compared with Sham-operated controls. In addition,... -
Nitroxergic Nerve Relaxes Rat Gastric Smooth Muscle by NO-cGMP Pathway
YoongSamYoon, HyoungChulChoi, YoungSookJung, JongHoKim, KwangYounLee, UyDongSohn, JeoungHeeHa, WonJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 5 369-378 (10 pages)
of rat. Isometric tension study, the measurement of single cell length, NADPH diaphorase stain of smooth muscle layers and neuronal nitric oxide synthase (nNOS) western blotting were performed. Sodium nitroprusside (SNP), a nitric oxide donor, relaxed the muscle strips precontracted by acetylcholine (ACh) in a concentration-dependent manner. Pretreatment of L-arginine decreased the contraction induced by electric field stimulation (EFS). Pretreatment of NG-nitro-L-arginine methyl ester (L-NAME),... -
Differential Effects of Nitric Oxide Synthase Inhibitors in Rats
Jun-HeeLee, ChangYellShin, BongSuKang, JiHoonJeong, KyeongBumChoi, YoungSilMin, JinHakKim, InHoiHuh, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.2 3 99-104 (6 pages)
We investigated the action of NOS inhibitors on NOS in rats. Both of nitric oxide synthase inhibitors, NG-monomethyl-L-arginine (L-NMMA, 3μM) or NG-nitro-L-arginine methylester (L-NAME, 30μM), augmented phenylephrine (PE, 107 M)-induced contraction which was inhibited by acetylcholine (ACh) in rat thoracic aorta. This augmentation by L-NAME or L-NMMA was attenuated with the treatment of NO precursor, arginine. ACh, however, decreased the augmentation induced by L-NMMA, but not by... -
Electroencephalographic Correlation Dimension Changes with Depth of Halothane
MaanGeeLee, EunJuPark, JungMeeChoi, MoonHanYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 5 491-499 (9 pages)
This study was designed to evaluate the efficacy of dynamic parameters, such as correlation dimension D2, by comparing spectral electroencephalographic (EEG) parameters. These parameters are used to estimate the depth of halothane anesthesia as defined by the presence of body movement in response to a tail clamp. Six rats were used and each of them was exposed to halothane sequentially at the concentrations of 0%, 0.5%, 1.0% and 1.5% for 30 min. A tail clamp was applied every five min and the... -
Characteristics of Hypoxic Pulmonary Vasoconstriction of the Rat Study by the Vessel Size and Location in the Lung
Sang-JinLeeKiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 10 321-328 (8 pages)
Pulmonary blood vessels with diameters of 200∼400 μm produce considerably more force in response to vasoconstrictor drugs than those which are either smaller or larger. We have therefore investigated whether or not hypoxic pulmonary vasoconstriction (HPV) is more powerful in vessels of these diameters. We have also looked at the possibility that vessels from different regions of the lung respond differently. To do this we have grouped vessels according to their location within the lung as... -
신성 고혈압쥐의 전신성 동맥계와 폐동맥계에 대한 EDRF 기능의 차이
이병호(Byung-Ho Lee), 신화섭(Hwa-Sup Shin), 허인회(In-Hoe Huh) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 2호 7 213-224 (12 pages)
급성 신성 고혈압쥐 (2-kidney, 1-ligation type)의 전신성 동맥계와 폐 동맥계에 대한 내피 의존적 혈관반응성을 규명하기 위하여, 적출 혈관 및 마취상태의 흰쥐에 대한 acetylcholine (ACh)의 혈관이완작용 및 혈압강하 작용을 측정하였다. 혈장 renin 활성(PRA)은 신동맥 결찰전 7.31 ± 0.63 ng/ml/hr A I에 비해 결찰 6 ~ 8일후에는 19 ~ 22 ng/ml/hr A I으로 유의성있게 증가하였으며, 이는 수축기혈압의 상승과 (154 ± 1.83{\rightarrow}190 ~ 215 mmHg) 일정한 상관성을 유지하였다. 신성 고혈압쥐 및 정상 혈압쥐의 흉곽... -
가토 교감신경절에서 무스카린성 수용체 아형과 니코틴성 수용체의 상호작용에 대한 연구
김종근(Jong Keun Kim), 류춘식(Choon Sik Rhu), 강삼석(Sam Suk Kang) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1992, 제 28권 제 2호 6 171-180 (10 pages)
교감신경절 전달에 무스카린성 수용체 아형과 니코틴성 수용체가 기능적으로 어떻게 작용하는지를 알아 보기 위하여 척수가토에서 척수를 통한 교감신경절전섬유의 자극에 의한 승압반응과 신경절 M1수용체 및 니코틴성 수용체 흥분제인 McN-A-343과 DMPP의 승압반응에 대한 M1수용체 길항제인 pirenzepine, M2수용체 길항제인 AF-DX116 및 니코틴성 수용체 길항제인 mecamylamine의 영향을 조사하였다. 먼저 M1 및 M2수용체의 작용을 선택적으로 차단하는 pirenzepine과 AF-DX116의 용량을 구하기 위해 chlorisondamine-처리가토에서의... -
토끼 대동맥 내피에서 A23187에 의하여 유리되는 혈관이완물질의 특성에 관한 연구
김치대(Chi-Dae Kim), 임병용(Byung-Yong Rhim), 홍승철(Sung-Chul Hong), 홍기환(Ki-Whan Hong) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1991, 제 27권 제 2호 5 125-134 (10 pages)
내피세포가 제거된 토끼의 적출 장간막 동맥에서 토끼의 대동맥 내피세포로 부터 A23187과 acetylcholine은 NO와 유사한 혈관 이완성 물질 (EDRF)을 유리한다. 이에 첨가하여 A23187은 acetylcholine과는 달리 superoxide anion에 의하여 파괴되지 않는 EDRF도 유리시킴을 확인하고 이의 특성에 대하여 연구하였다. 정상적인 생리영양액에서는 A23187과 acetylcholine의 용량-반응 곡선은 내피세포에 의존하지 않는 sodium nitroprusside의 곡선과 유사하였다. 이들은 methylene blue에 의하여 억제되었다. Hypoxanthine (HX)과 xanthine... -
흰쥐에서 대상회전 제거가 위액분비에 미치는 영향
박형진(Park, Hyoung-Jin), 안병태(Ahn, Byung-Tae), 조양혁(Jo, Yang-Hyeok) 대한생리학회 대한생리학회지 6 Pages
대한생리학회 대한생리학회지 1977, 제 11권 제 2호 11 67-72 (6 pages)
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Morphometric Characterisation of Root-Knot Nematode Populations from Three Regions in Ghana
Seloame Tatu Nyaku, Hanif Lutuf, Eric Cornelius 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 6호 9 544-554 (11 pages)
a single nematode from Afrancho (AF4) that fell into Group Ⅲ. Biplots for male populations indicate, body length DEGO, greatest body width, and gubernaculum length serving as variables distinguishing Group 1 and Group 2 populations. These same groupings from the PCA were reflected in the dendogram generated using Agglomerative Hierarchical Clustering (AHC). This study provides the first report on morphometric characterisation of M. incognita male and juvenile populations in Ghana showing... -
Genetic Variability and Geographical Distribution of Mycotoxigenic Fusarium verticillioides Strains Isolated from Maize Fields in Texas
한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2015, 31권 3호 1 203-211 (9 pages)
Maize is the dominant cereal crop produced in the US. One of the main fungal pathogens of maize is Fusarium verticillioides, the causative agent of ear and stalk rots. Significantly, the fungus produces a group of mycotoxins - fumonisins - on infested kernels, which have been linked to various illnesses in humans and animals. Nonetheless, durable resistance against F. verticillioides in maize is not currently available. In Texas, over 2.1 million acres of maize are vulnerable to fumonisin...
