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1261.

지연성 운동장애 환자에서 뇌 척수액 丫-Aminobutyric Acid 농도에 관한 연구

권준수, 김재진, 우종인 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1990, 제 29권 제 6호 5 1245-1254 (10 pages)

권준수, 김재진, 우종인 저
...
- 3,000원
1262.

Ethanol 및 Acetaldehyde Patch Test 결과에 대한 H I, H2-Histamine Antagonist와 Disulfiram의 영향에 관한 연구

정신, 김학렬, 이민규 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 1991, 제 30권 제 1호 6 54-65 (12 pages)

정신, 김학렬, 이민규 저
...
- 4,100원
1263.

Regulatory Action of Protein Tyrosine Kinase in Intracellular Calcium Mobilization in C5a-stimulated Neutrophils

최원태(Won-Tae Choi), 한은숙(Eun-Sook Han), 이정수(Chung-Soo Lee) 대한약리학회 대한약리학잡지 8 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 13 417-424 (8 pages)

최원태(Won-Tae Choi), 한은숙(Eun-Sook Han), 이정수(Chung-Soo Lee) 저
...
- 3,000원
The present study was done to examine the involvement of protein kinase C and protein tyrosine kinase in intracellular Ca2+ mobilization in C5a-stimulated neutrophils. Although protein kinase C inhibitors, staurosporine and H-7 inhibited intracellular Ca2+ release in C5a-stimulated neutrophils, they did not affect Ca2+ influx across the plasma membrane and elevation of [Ca2+]i C5a-induced intracellular Ca2+ release and Ca2+ influx were inhibited by protein tyrosine kinase inhibitors, genistein...
1264.

Effect of Hydroxocobalamin on Contractile Responses to Phenylephrine during Administration of Inhalational Anesthetics in Lipopolysaccharide-Treated Rat Aortae

김인겸(In Kyeom Kim), 양은경(Eun Kyoung Yang) 대한약리학회 대한약리학잡지 8 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 9 381-388 (8 pages)

김인겸(In Kyeom Kim), 양은경(Eun Kyoung Yang) 저
...
- 3,000원
The hemodynamic changes in septic patients produced by inhalational anesthetics are sufficient to threaten the anesthesiologists. The effect of hydroxocobalamin, a vitamin B12a, on contractile responses to phenylephrine during administration of inhalational anesthetics were evaluated in aortic ring preparations obtained from LPS-treated rats. The sepsis was developed by intraperitoneal injection of LPS (1.5 mg/kg for l8h) and confirmed by iNOS expression using RT-PCR. Statistical significances...
1265.

Effects of Extracellular Ca++on PKC or cAMP-stimulated Increases in LH Release and LHβSubunit mRNA Levels in Rat Anterior Pituitary Cells

박덕배(Deok-bae Park), 김창미(Chang-mee Kim), 천민석(Min-seok Cheon), 유경자(Kyung-za Ryu) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 6 347-356 (10 pages)

박덕배(Deok-bae Park), 김창미(Chang-mee Kim), 천민석(Min-seok Cheon), 유경자(Kyung-za Ryu) 저
...
- 3,000원
We examined the effects of EGTA and verapamil on phorbol ester-and forskolin-stimulated LH releases and LHβ subunit mRNA levels in order to verify the role of extracellular Ca++ on PKC- or cAMP-induced increases in LH release and LHβ subunit mRNA levels in cultured anterior pituitary cells of rat. Forskolin-stimulated LHβ subunit mRNA levels as well as LH release were all suppressed by prevention of Ca++ mobilization from extracellular environment, after the treatment of EGTA as a Ca++...
1266.

Oxidative Stress and HSP70 Expression Upon Cerebral Isehemia-Reperfusion in Mongolian Gerbil

박영미(Young-Mee Park), 김철훈(Chul-Hoon Kim), 도윤정(Yun-Jeong Do), 최은미(Eun-Mi Choi), 안영수(Young-Soo Ahn) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 5 335-346 (12 pages)

박영미(Young-Mee Park), 김철훈(Chul-Hoon Kim), 도윤정(Yun-Jeong Do), 최은미(Eun-Mi Choi), 안영수(Young-Soo Ahn) 저
...
- 4,100원
A critical role of oxygen-derived free radicals has been implicated in ischemia/reperfusion (I/R)-induced brain damage. In this study, we have produced experimental I/R to the brains of Mongolian gerbil (Meriones unguiculatus) by a transient occlusion and release of the common carotid arteries. We have attempted to determine whether the oxidative stress is generated upon I/R and whether this oxidative stress is linked to the cell damage. Since hippocampus has been suggested as one of the most...
1267.

Effects of Site-Mutagenesis of an Amino Acid Triplet Repeat atM1 and M2 Muscarinic Receptors on Receptor Function

이석용(Seok-Yong Lee), 이상복(Sang-Bok Lee) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 3 311-322 (12 pages)

이석용(Seok-Yong Lee), 이상복(Sang-Bok Lee) 저
...
- 4,100원
Both M1 and M2 muscarinic receptors contain a triplet of amino acid residues consisting of leucine (L), tyrosine (Y) and threonine (T) at C-terminus ends of the second putative transmembrane domains. This triplet is repeated as LYT-LYT in M2 receptors at the interface between the second transmembrane domain and the first extracellular loop. Interestingly, however, it is repeated in a transposed fashion (LYT-TYL) in the sequence of M1 receptors. In this work, we employed site-directed mutagenesis...
1268.

Effect of K+-channel Blockers on the A1-adenosine Receptor-Coupled Regulation of Electrically-Evoked Norepinephrine Release in the Rat Hippocampus

최봉규(Bong Kyu Choi), 김상훈(Sang Hoon Kim) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 2 301-310 (10 pages)

최봉규(Bong Kyu Choi), 김상훈(Sang Hoon Kim) 저
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- 3,000원
Since it has been reported that the depolarization-induced NE release is inhibited by activation of presynaptic A1-adenosine heteroreceptor in hippocampus, a large body of experimental data on the post-receptor mechanism of this process has been accumulated. But, the post-receptor mechanism of presynaptic A1-adenosine receptor on the NE release has not been clearly elucidated yet. Therefore, it was attempted to clarify the participation of K+-channel in the post-receptor mechanisms of the...
1269.

Pharmacological Action Mechanism(s) of Vasodilator Effect of Calcitonin Gene-related Peptide in Rat Basilar Arteries

임병용(Byung Yong Rhim), 홍선화(Sun Hwa Hong), 김치대(Chi Dae Kim), 이원석(Won Suk Lee), 김동헌(Dong Heon Kim), 홍기환(Ki Whan Hong) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 5 39-50 (12 pages)

임병용(Byung Yong Rhim), 홍선화(Sun Hwa Hong), 김치대(Chi Dae Kim), 이원석(Won Suk Lee), 김동헌(Dong Heon Kim), 홍기환(Ki Whan Hong) 저
...
- 4,100원
In the present study, we observed change in intracellular Ca2+([Ca2+]i) as measured with the fluorescent Ca2+-indicator fura-2 in association with force development of the rat basilar arteries during activation byK+ depolarizing solution and U46619, a thromboxane analogue, in the absence and the presence of calcitonin-gent related peptide (CGRP). CGRP (30 and 100 nM) caused a concentration-dependent inhibition of U46619-induced contraction with decrease in [Ca2+]i, whereas it did not exert any...
1270.

Role of Adenosine and Protein Kinase C in the Anti-ischemic Process of Ischemic Preconditioning in Rat Heart

유호진(Ho-Jin You), 박종완(Jong-Wan Park), 김명석(Myung-Suk Kim) 대한약리학회 대한약리학잡지 8 Pages

대한약리학회 대한약리학잡지 1996, 제 32권 제 1호 4 31-38 (8 pages)

유호진(Ho-Jin You), 박종완(Jong-Wan Park), 김명석(Myung-Suk Kim) 저
...
- 3,000원
The protective effect of ischemic preconditioning (IP) on ischemia-reperfusion injury of heart has been reported in various animal species, but the mechanism is unclear. In an attempt to elucidate the mechanism of IP, we examined the effects of blockers against adenosine and protein kinase C in preconditioned heart of rat. The hearts perfused with oxygen-saturated Krebs-Henseleit solution by Langendorff method were exposed to 30 min global ischemia followed by 20 min reperfusion. IP was...

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