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A case of protein Losing nephropathy in a dog infected with canine Babesia gibsoni
HaJungKim, ChulPark, DongInJung, ByeongTeckKang, JuWonKim, ChaeYoungLim, HeeMyungPark 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2006, 제 46권 제 1호 14 77-81 (5 pages)
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개에 발생한 반음양증
권영삼, 박천호, 장광호, 토시후미오야마다 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 3호 14 411-416 (6 pages)
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Therapeutic effects of orally administered CJLP55 for atopic dermatitis via the regulation of immune response
KyeongEunHyung, SooJeongKim, YeWonJang, DaKyoungLee, KeeHyeobHyun, ByoungSeokMoon, BongjoonKim, HeeyoonAhn, So-YoungPark, UyDongSohn, EonS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.3 8 335-343 (9 pages)
Atopic dermatitis (AD) is an inflammatory skin condition accompanied by symptoms such as edema and hemorrhage. Kimchi is a traditional fermented Korean dish consisting of various probiotics. In this study, the therapeutic effect of Lactobacillus plantarum CJLP55 isolated from Kimchi was studied in AD-induced mice. Orally administered Lactobacillus strain, CJLP55, suppressed AD symptoms and high serum IgE levels. CJLP55 administration reduced the thickness of the epidermis, infiltration of mast... -
Increasing injection frequency enhances the survival of injected bone marrow derived mesenchymal stem cells in a critical limb ischemia animal model
WoongCholKang, PyungChunOh, KyounghoonLee, TaehoonAhn, KyungheeByun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 12 657-667 (11 pages)
Critical limb ischemia (CLI) is one of the most severe forms of peripheral artery diseases, but current treatment strategies do not guarantee complete recovery of vascular blood flow or reduce the risk of mortality. Recently, human bone marrow derived mesenchymal stem cells (MSCs) have been reported to have a paracrine influence on angiogenesis in several ischemic diseases. However, little evidence is available regarding optimal cell doses and injection frequencies. Thus, the authors undertook... -
CTLA-4-Tg/CD-28-KO Mice Exhibit Reduced T Cell Proliferation in vivo Compared to CD-28-KO Mice in a Graft-versus-host Disease Model
Jong-SunYoo, Yun-JungLee, JooWonYoon, KyeongEunHyung, KwangWooHwang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 10 349-353 (5 pages)
Activated T cells express inhibitory receptors such as CTLA-4 that can downregulate immune responses. Blockade of or genetic deficiency in CTLA-4 can result in autoimmunity. Therefore, strategies to increase the inhibitory function of CTLA-4 may be attractive in settings of undesirable T cell responses such as autoimmunity or transplant rejection. We have tested the hypothesis that transgenic constitutive expression of CTLA-4 can further attenuate immune responses when compared with normal... -
Curcumin Attenuates Glial Cell Activation But Cannot Suppress Hippocampal CA3 Neuronal Cell Death in i.c.v. Kanic Acid Injection Model
JaeyoungCho, Pil-JaeKong, WanjooChun, Yeo-OkMoon, Yee-TaePark, So-YoungLim, Sung-SooKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 3 307-310 (4 pages)
Kainic acid (KA) is a structural analogue of glutamate that interacts with specific presynaptic and postsynaptic receptors to potentiate the release and excitatory actions of glutamate. Systemic or intracerebroventricular (i.c.v.) administration of KA to experimental animals elicits multifocal seizures with a predominantly limbic localization, and results in neuronal death of cornu ammonia 1 (CA1), reactive gliosis and biochemical changes in the hippocampus and other limbic structures. Several... -
Prevention of Diabetes Using Adenoviral Mediated Hepatocyte Growth Factor Gene Transfer in Mice
Hye-JeongLee, Hyun-JeongKim, Mee-SookRoh, Jae-IkLee, Sung-WonLee, Dong-SikJung, Duk-KyuKim, Mi-KyoungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 3 261-266 (6 pages)
Type 1 diabetes is an organ-specific autoimmune disease caused by the cytotoxic T cells-mediated destruction of the insulin-producing beta cells in the Langerhans pancreatic islets. Hepatocyte growth factor (HGF) is a potent mitogen and a promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF via viral vector in the development of streptozotocin (STZ)-induced diabetes in mice, we have developed an adenoviral vector genetically engineered to carry... -
두부외상으로 인해 발생한 기면증 1예
박성근, 김진세, 김린, 정인과 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 1호 23 240-246 (7 pages)
검사상 특이한 이상소견은 없었다. 우선 저자들은 전환장애나 꾀병을 먼저 의심 하게 되었다. 그러나 자세한 병력청취와 관찰상 낮동안의 수면발작과 야간 수면에서의 어려움이 있었고, 야 간수면다원검사, 수면잠복기 반복검사, 그리고 탈력발작 삽화 동안의 근전도 검사 등을 통해 기면증으로 진 단되었다. 또한 human leukocyte antigen(HLA)-DR2 검사에서 음성 결과를 보여 본 환자의 기면증이 원 발성이 아님이 시사되었다. 치료약물로 imipramine을 투여하자 탈력발작의 증상은 급격히 감소하였다. 따라 서 두부외상 후 졸리움과... -
알코올에 의한 숙취상태에서 Cytokine 생성능의 변화
김원, 김대진, 윤수정, 최보문, 김정수, 임현국, 고효진 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2002, 제 41권 제 6호 4 991-997 (7 pages)
연구목적： 알코올을 섭취하고 8~16시간 후에 오는 불쾌한 효과를 일반적으로 숙취라고 한다. 본 연구자들은 정상인에서 실험적으로 숙취를 유도한 후 알코올 복용 전과 숙취 상태의 cytokine 생성능을 조사하여 숙취 상태와 면역계와의 연관을 알아보았다. 방 법： 본 연구는 최근 6개월 동안 내외과적 질환 및 정신과적 질환이 없는 정상 성인 남자 13명을 대상 으로 하였다. 대상군들이 1.5g/kg의 알코올을 섭취한 13시간 이후를 실험적 숙취상태로 정의하였다. 실험일 오전 8시에 혈액을 채취하였으며 알코올 섭취 13시간 이후인 다음...
