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Effects of Angiotensin Converting Enzyme Inhibition on Gene Expression of the Renin-Angiotensin System in Rats
YoungRaeLee, MiYoungLee, WoonJungKim, WonJungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 14 771-778 (8 pages)
To investigate interaction of angiotensin converting enzyme (ACE) inhibitor with local tissue renin- angiotensin system (RAS), changes in gene expression of the RAS components in various tissues in response to chronic administration of an ACE inhibitor, enalapril, were examined in Sprague-Dawley male rats. Enalapril was administered in their drinking water (3∼4 mg/day) over 8 wk. Plasma and renal ACE activity increased significantly after 4 and 8 wk of enalapril treatment. Renin levels of the... -
주요우울증과 세로토닌수송단백질 유전자의 다형성
임신원, 손성은, 김도관, 김이영 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 1호 18 199-207 (9 pages)
연구목적: 세로토닌 수송단백질(serotonin transporter, 5-hydroxytryptamine transporter, 5-HTT)은 세로토닌 계에서 이루어 지는 신경전달을 시냅스전 신경세포로 재흡수함으로써 종결시키는 데 중요한 역할을 하고, 삼 환계 항우울제나 선택적인 세로토닌 재흡수 차단제 등의 주요 항우울제의 작용 개시 부위로 알려져 왔다. 본 연구에서는 5-HTT 유전자와 주요 우울증 간의 관련성을 알아보고 이 유전자의 유전자형 특성이 항우울제 에 대한 반응정도와 관련이 있는지 알아보고자 하였다. 방 법: 142명의 우울증 환자들(주요... -
Effect of Hydroxocobalamin on Contractile Responses to Phenylephrine during Administration of Inhalational Anesthetics in Lipopolysaccharide-Treated Rat Aortae
김인겸(In Kyeom Kim), 양은경(Eun Kyoung Yang) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 9 381-388 (8 pages)
The hemodynamic changes in septic patients produced by inhalational anesthetics are sufficient to threaten the anesthesiologists. The effect of hydroxocobalamin, a vitamin B12a, on contractile responses to phenylephrine during administration of inhalational anesthetics were evaluated in aortic ring preparations obtained from LPS-treated rats. The sepsis was developed by intraperitoneal injection of LPS (1.5 mg/kg for l8h) and confirmed by iNOS expression using RT-PCR. Statistical significances... -
Oxidative Stress and HSP70 Expression Upon Cerebral Isehemia-Reperfusion in Mongolian Gerbil
박영미(Young-Mee Park), 김철훈(Chul-Hoon Kim), 도윤정(Yun-Jeong Do), 최은미(Eun-Mi Choi), 안영수(Young-Soo Ahn) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1996, 제 32권 제 3호 5 335-346 (12 pages)
A critical role of oxygen-derived free radicals has been implicated in ischemia/reperfusion (I/R)-induced brain damage. In this study, we have produced experimental I/R to the brains of Mongolian gerbil (Meriones unguiculatus) by a transient occlusion and release of the common carotid arteries. We have attempted to determine whether the oxidative stress is generated upon I/R and whether this oxidative stress is linked to the cell damage. Since hippocampus has been suggested as one of the most... -
Identification of strA-strB Genes in Streptomycin-Resistant Pseudomonas syringae pv. actinidiae Biovar 2 Strains Isolated in Korea
Young Sun Lee, Gyoung Hee Kim, Young Jin Koh, Jae Sung Jung 한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 5호 8 489-493 (5 pages)
Bacterial canker is a devastating disease of kiwifruit caused by the bacterium Pseudomonas syringe pv. ac- tinidiae. Canker disease of kiwifruit in Korea has been controlled using streptomycin for more than two de- cades. Four streptomycin-resistant strains, belonging to biovar 2, which are found only in Korea, were col- lected between 2013 and 2014 from different orchards located in Jeju, Korea. The genetic background for streptomycin resistance among P. syringe pv. actinidiae strains were... -
Variability of Stem-Base Infestation and Coexistence of Fusarium spp. Causing Crown Rot of Winter Wheat in Serbia
Radivoje Jevtić;Nemanja Stošić;Vesna Župunski;Mirjana Lalošević;Branka Orbović 한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 2 553-563 (11 pages)
Investigations related with factors influencing root and crown rot are rare and mainly related to farming practice and soil management. The main objective of this study was to examine broader range of factors influencing stem-base infestation of winter wheat in the field conditions. The effect of spatial distribution of infected plants on disease index (DIs) assessments was also investigated. Analysis of factors influencing DIs of crown rot of wheat demonstrated significant influence of the... -
Comparative Genome Analysis of Rathayibacter tritici NCPPB 1953 with Rathayibacter toxicus Strains Can Facilitate Studies on Mechanisms of Nematode Association and Host Infection
한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 4호 3 370-381 (12 pages)
Rathayibacter tritici, which is a Gram positive, plant pathogenic, non-motile, and rod-shaped bacterium, causes spike blight in wheat and barley. For successful pathogenesis, R. tritici is associated with Anguina tritici, a nematode, which produces seed galls (ear cockles) in certain plant varieties and facilitates spread of infection. Despite significant efforts, little research is available on the mechanism of disease or bacteria-nematode association of this bacterium due to lack of genomic... -
Efficient Transmission and Propagation of Tomato Chlorosis Virus by Simple Single-Leaflet Grafting
한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 3호 13 345-349 (5 pages)
Tomato chlorosis virus (ToCV), a member of the genus Crinivirus, has caused an epidemic disease in tomato worldwide. ToCV is phloem-limited and transmitted by whiteflies in a semi-persistent manner, but not by mechanical inoculation. Experimental propagation of ToCV has been performed primarily by using whitefly-mediated inoculation. To develop a simple and convenient method for transmission of ToCV, we investigated grafting single-leaflets from tomato plants infected with ToCV to recipient... -
Efficacy of Tissue Culture in Virus Elimination from Caprifig and Female Fig Varieties (Ficus carica L.)
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 3호 7 288-295 (8 pages)
Fig mosaic disease (FMD) is a viral disease that spreads in all Tunisian fig (Ficus carica L.) orchards. RT-PCR technique was applied to leaf samples of 29 fig accessions of 15 fig varieties from the fig germplasm collection of High Agronomic Institute (I.S.A) of Chatt-Mariem, to detect viruses associated to FMD. Analysis results show that 65.5% of the accessions (19/29) and 80.0% (12/15) of the fig varieties are infected by FMD-associated viruses. From all fig accessions, 41.4% of them are with...


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