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681.

Cytochrome P450 2E1 Activity in a Korean Population

Dou-HyunMuhn, Ji-MinChae, Jae-YongBahn, Hae-JungSong, Hyung-KeeKim, Jun-TackKwon, Dong-RyulSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 16 597-602 (6 pages)

Dou-HyunMuhn, Ji-MinChae, Jae-YongBahn, Hae-JungSong, Hyung-KeeKim, Jun-TackKwon, Dong-RyulSohn 저
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- 3,000원
excreted in 8 hr urine expressed as the percentage was 48.2 13.8%. The frequency distribution of percentage of the administered dose excreted as the 6-hydroxy metabolite was unimodally distributed in the subjects studied. However, the values showed wide (7-fold) interindividual difference, ranged from 11.6% to 79.8% of the dose of chlorzoxazone. Thus, it was considered that the pharmacogenetic characteristics of CYP2E1 in a Korean population did not represent multimodal distribution in the...
682.

Nitric Oxide Prevents the Bovine Cerebral Endothelial Cell Death Induced by Serum-Deprivation

ChulHoonKimYoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 6 515-521 (7 pages)

ChulHoonKimYoungSooAhn 저
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- 3,000원
Endothelial cells play a central role in the inflammatory processes, and activation of nuclear factor kappa B (NF-κB) is a key component in that inflammatory processes. Previously, we reported that tumor necrosis factor alpha(TNFα) had protective effect of cell death induced by serum deprivation and this protection was related to NF-κB activation. Inducible nitric oxide synthase (iNOS) is a member of the molecules which transcription is regulated mainly by NF-κB. And the role of nitric...
683.

Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. II. Inhibitory Effects of ANG II on Na+ Uptake

HoJaeHan, SooHyunPark, HyunJuKoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 9 425-434 (10 pages)

HoJaeHan, SooHyunPark, HyunJuKoh 저
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- 3,000원
dose dependent biphasic effects on fluid transport in the proximal tubule. However, respective roles of different signaling pathways in mediating these effects remain unsettled. The aim of the present study was to examine signaling pathways at high doses of ANG II on the Na+ uptake of primary cultured rabbit renal proximal tubule cells(PTCs) in hormonally defined serum-free medium. High concentrations of ANG II (＞10-9 M) inhibited Na+ uptake and increased [Ca2+]i level in the PTCs. However, low...
684.

Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. I. Stimulatory Effects of ANG II on Na+ Uptake

HoJaeHan, HyunJuKoh, SooHyunPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 8 413-423 (11 pages)

HoJaeHan, HyunJuKoh, SooHyunPark 저
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- 4,000원
to examine signaling pathways of low dose of ANG II on the Na+ uptake of primary cultured rabbit renal proximal tubule cells (PTCs) in hormonally defined serum-free medium. The results were as follows: 1) 10-11 M ANG II has a significant stimulatory effect on growth as compared with control. Alkaline phosphatase exhibited significantly increased activity. However, leucine aminopeptidase and γ-glutamyl transpeptidase activity were not significant as compared with control. In contrast to 10-11 M...
685.

Platelet-Activating Factor Enhances Interleukin-1 Activity by Alveolar Macrophages Inhibition by PAF Specific Receptor Antagonists

JiheeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 10 201-208 (8 pages)

JiheeLee 저
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- 3,000원
It is becoming increasingly clear that the inflammatory reaction can be ascribed to a complex array of mediators generated and released from activated phagocytes. In this study, the effect of PAF on interleukin-1(IL-1) activity by rat alveolar macrophages(AM) was examined using thymocyte proliferation assay in the supernate of sample obtained after 24 hr culture. When AM were cultured with PAF alone, no change in IL-1 activity was observed. However, the combined addition of PAF and muramyl...
686.

Functional Characteristics of Neutral Amino Acid Transporter in Opossum Kidney (OK) Cells

JaeSukWoo, MoonHwanPark, SaeOkOh, JinSupJung, YongKeunKim, SangHoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 8 185-193 (9 pages)

JaeSukWoo, MoonHwanPark, SaeOkOh, JinSupJung, YongKeunKim, SangHoLee 저
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- 3,000원
The characteristics of Na+-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed a broad spectrum affinity to neutral amino acids regardless of their different side chains including branched or aromatic, indicating that the Na+-dependent cycloleucine uptake in OK cells is mediated by System Bo or System Bo-like transporter rather than the...
687.

Study on Ginseng Protopanaxadiol and Protopanaxatriol Saponins- Induced Antinociception

Young-HeeShin, Seok-ChangKim, Ji-WonHan, Dae-HoonKim, Sang-SubHan, Dong-HoShin, Seung-YeolNah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 4 143-149 (7 pages)

Young-HeeShin, Seok-ChangKim, Ji-WonHan, Dae-HoonKim, Sang-SubHan, Dong-HoShin, Seung-YeolNah 저
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- 3,000원
We studied the effects of ginseng protopanaxadiol (PD) and protopanaxatriol (PT) saponins on the analgesia using several pain tests such as writhing, formalin, and tail-flick test. Using mouse, pretreatment of PD or PT saponins (i.p.) induced inhibition of abdominal constrictions caused by 0.9% acetic acid administration(i.p.). The AD50 was around 27 (17-43) mg/kg for PD and 13.5 (3-61) mg/kg for PT saponins in writhing test. Both PD and PT saponins also showed the inhibition of bitings and...
688.

Pharmacological Evidence that Cromakalim Inhibits Ca2+ Release from Intracellular Stores in Porcine Coronary Artery

ByungYongRhim, SunHwaHong, ChiDaeKim, WonSukLee, KiWhanHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 4 27-34 (8 pages)

ByungYongRhim, SunHwaHong, ChiDaeKim, WonSukLee, KiWhanHong 저
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- 3,000원
In the present study, it was aimed to further indentify the intracellular action mechansm of cromakalim and levcromakalim in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine caused an increase in intracellular free Ca2⁢ ([Ca2⁢]i) in association with a contraction in a concentration-dependent manner. Cromakalim (1 ㄍM) caused a reduction in acetylcholine-induced increased [Ca2⁢]i not only in the mormal...
689.

Physical Activity of Patients with Chronic Schizophrenia and Related Clinical Factors

Sook-Hyun Lee, Gyurin Kim, Chul-Eung Kim, Seunghyong Ryu 대한신경정신의학회 Psychiatry Investigation 7 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 10 811-817 (7 pages)

Sook-Hyun Lee, Gyurin Kim, Chul-Eung Kim, Seunghyong Ryu 저
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- 3,000원
the low physical activity (PA) of patients with chronic schizophrenia. Methods_PA was measured in 50 outpatients with chronic schizophrenia using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Psychopathology, psychosocial functioning, and extrapyramidal symptoms were assessed using the 18 item-Brief Psychiatric Rating Scale (BPRS-18), Global Assessment of Functioning (GAF), and Drug-Induced Extrapyramidal Symptom Scale (DIEPSS), respectively. We examined differences in...
690.

항정신병약물에 의한 급성 추체외로증후군에서의 감각증상

신유호, 윤도준, 신영우, 장환일 대한신경정신의학회 신경정신의학 10 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 2호 13 358-367 (10 pages)

신유호, 윤도준, 신영우, 장환일 저
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- 3,000원

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