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전체 선택해제
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본문검색 결과만 보기
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재료상수가 상이한 요소로 이루어진 적층평판형구조물의 Brazier효과에 관한 연구
김재열, 한상을, 권택진 한국전산구조공학회 전산 구조 공학 9 Pages
한국전산구조공학회 전산 구조 공학 1996, Vol.9 No.3 199-207 (9 pages)
Brazier현상과 유사한 현상이 발생한다. 본 논문에서는 평판에서의 Brazier현상을 규명하기 위하여 3층 적층모델을 만들어 각층의 재료정수가 현저히 다른 경우 어떠한 현상이 일어나는 가를 실험적으로 규명하였고, 이론해석을 위하여 스프링모델을 사용하였다. 본 논문의 모델에서 알 수 있듯이 중간층의 재료상수가 상하층 요소의 재료상수 보다 뚜렷하게 작은 경우 중간층의 거동이 현저히 크게됨을 알 수 있었다. 즉, 본 논문에서 채택한 모델의 경우에 있어서도 원통관에서 일어나는 Brazier형상이 일어나고 있음이 실험적 그리고... -
Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model
Se Eun Kim, Tae Hyun Kim, Shin Ae Park, Won Tae Kim, Young Woo Park, Jae Sang Ahn, Manbok Jeong, Min-Young Kim, Kangmoon Seo 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 15 245-251 (7 pages)
a key role in the prevention and reduction of periodontitis progression. Horse chestnut (Aesculus hippocastanum L.) extracts have been used as treatments for inflammatory disease, traditionally. This study assessed the clinical effect as a MMP inhibitor of horse chestnut leaf extract ALH-L1005 on periodontitis. ALH-L1005 was obtained from horse chestnut leaf and its MMP inhibitory activities estimated. Periodontitis was induced in beagles assigned to 4 groups and medicated for 6 weeks: low dose... -
Involvement of the Ca signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
Yingxiao Fu, Jianhong Gu, Yi Wang, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zong-Ping Liu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 3 151-156 (6 pages)
The purpose of this study was to determine whether the Ca signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were incubated with macrophage colony-stimulating factor (M-CSF) + receptor activator of nuclear factor-κB ligand (RANKL) to stimulate osteoclastogenesis and then treated with different concentrations of OPG, an inhibitor of osteoclast differentiation. The intracellular Ca concentration [Ca]i and... -
원저 : 말의 운동 스트레스에 관한 새로운 생물지표
이승우, 오다영, 김명철, 김용백, 류덕영 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 4호 6 247-252 (6 pages)
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Effects of Watercress Containing Rutin and Rutin Alone on the Proliferation and Osteogenic Differentiation of Human Osteoblast-like MG-63 Cells
HanbitHyun, HeajinPark, JaehoonJeong, JihyeKim, HaesungKim, HyunIlOh, HyeSeongHwang, HaHyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 10 347-352 (6 pages)
Most known osteoporosis medicines are effective for bone resorption, and so there is an increasing demand for medicines that stimulate bone formation. Watercress (N. officinale R. Br.) is widely used as a salad green and herbal remedy. This study analyzed a watercress extract using ultra-performance liquid chromatography/mass spectrometry, and identified a rutin as one of its major constituents. Osteogenic-related assays were used to compare the effects of watercress containing rutin (WCR) and... -
Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells
YoungRanPark, JaeSoonEun, HwaJungChoi, ManojNepal, DaeKeunKim, Seung-YongSeo, RihuaLi, WooSungMoon, Nam-PyoCho, Sung-DaeCho, TaeSungBae, By 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 2 417-424 (8 pages)
Osteoclasts, derived from multipotent myeloid progenitor cells, play homeostatic roles in skeletal modeling and remodeling, but may also destroy bone in pathological conditions such as osteoporosis and rheumatoid arthritis. Osteoclast development depends critically on a differentiation factor, the receptor activator of NF-ՊB ligand (RANKL). In this study, we found that the hexane soluble fraction of the common fig Ficus carica (HF6-FC) is a potent inhibitor of osteoclastogenesis in... -
Effects of R. Glutinosa and E. Senticosus on Postmenopausal Osteoporosis
SooYeonOh, DipendraKumarAryal, Yoon-GyoonKim, , Hyung-GunKim, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 7 121-127 (7 pages)
In this study, we investigated the therapeutic effects of a novel formulation of low-dose calcium and vitamin D3, blended with Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max (RE), in postmenopausal women. The controls were given either a placebo or high dose calcium and vitamin D3 (CaD). Bone mineral density (BMD) in the L2-3 lumber spines and femur regions was assessed, and serum osteocalcin, bone-specific alkaline phosphatase (BALP), and cross-linked N-telopeptide... -
Involvement of ERK1/2 and JNK Pathways in 17β-estradiol Induced Kir6.2 and SK2 Upregulation in Rat Osteoblast-like Cells
Jung-WookKim, Eun-KyoungYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 6 199-206 (8 pages)
In addition, treatment of cells with U0126, a specific inhibitor of extracellular receptor kinases (ERK)1/2, and SP600125, a specific inhibitor of c-jun N-terminal kinase (JNK) blocked the enhancing effects of 17β-E2 on SK2 and Kir6.2 protein expressions. On the other hand, blocking of p38 mitogen-activated protein kinase had no effect. Taken together, these results indicate that 17β-E2 modulates SK2 and Kir6.2 expressions through the estrogen receptor, involving ERK1/2 and JNK activations. -
불면증시의 저혈소판 Serotonin 치
최번숙, 정희연, 한선호 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1988, 제 27권 제 3호 5 487-495 (9 pages)
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백서에서 동통에 미치는 Phenobarbital 효과의 재평가
소병겸(Byoung-Gyoum So), 김기원(Kee-Won Kim), 고명규(Myoung-Kyu Ko), 양원모(Won-Mo Yang), 조규박(Kyu-Park Cho) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1986, 제 22권 제 2호 2 88-95 (8 pages)
Kd치와는 달리 Bmax를 현저히 감소시켰다. 5) Phenobarbital 장기처리에 의한 HPL변동, 뇌내 β-endorphin함량변동 그리고 opiate receptor Bmax변동 삼자간에는 유의한 상관관계가 있었다. 6) 적출vas deferens 표본에서 phenobarbital 장기처리는 morphine의 ID50은 증가시키고 maximum effect는 감소시키나 naloxone에 대한 pA2 치에는 영향을 미치지 못하였다. 이상의 실험성적은 phenobarbital이 일시적인 과민동통 효과에 이어 진통효과를 갖고 있으며, phenobarbital의 진통효과는 뇌내 β-endorphin함량 증가와 이로 인한...
