Fibiger 가 1913 년(年)에 저단백식이(低蛋白食餌)로 기른 백서(白鼠)의 전위부(前胃部)에 비후성(肥厚性) 궤양(潰瘍) 발생(發生)을 관찰(觀察)한 이래(以來) 많은 학자(學者)들에 의하여 같은 궤양(潰瘍)을 발생(發生)시키었다. 본교실(本敎室)에서는 저단백식이(低蛋白食餌)로 기른 백서(白鼠)에게 진동긴박(振動緊迫)을 가(加)하면 단시일(短時日)안에 전위부(前胃部)에 비후성궤양(肥厚性潰瘍)이 발생(發生)되는 것을 관찰(觀察)하였다. 본실험(本實驗)은 riboflavin 혹은 thiamine 결핍(缺乏) 백서(白鼠)에게 진동긴박(振動緊迫)을 가(加)하고 그 전위부(前胃部) 궤양(潰瘍) 발생(發生) 여하(如何)를 관찰(觀察)한 것이다.
Since the production of hyperplastic ulcers of forestomachs of rats fed on low protein diet by Fibiger in 1913, many investigators produced the same lesions on the rats. In this laboratory, the hyperplastic ulcers of forestomachs of rats fed on low protein diet was produced in a shorter period by shaking the rats. In this experiment, production of ulcers of forestomachs of the riboflavin or thiamine deficient rats by giving shaking stress was investigated. The results were follows; No ulceration of forstomachs of the riboflavin or thiamine deficient rats fed on 20% casein diet was produced by shaking the rats. However, severe hyperplastic ulcers of forestomachs of the thiamine deficient rats fed on 91% rice diet were produced by shaking the rats, while no change of those of rats fed 91 % rice diet were observed by the same treatment. So it is concluded that the thiamine deficiency accelerates the production of hyperplastic ulcers of the forestomachs of rats fed on low protein diet.
