The study on cytotoxicities of domestic antitumour crude drugs were carried out in order to evaluate the antitumour activity. The eleven crude drugs were studied in this paper. No cytotoxicities were observed both at 0.1ml of water extracts and alcohol extracts deuted against monkey kidney cell and HeLa-cell after 3 days cultivation at $37^{circ}C$. The sample shown the heavy cytotoxicities against monkey kidney cell at 0.3ml alcohol extracts diluted sample solution are Lonicerae Flos and Puchrestae Radix.