Since moore diagnosed brain tumor with radioiodine labelled fluoroscein in 1948, many authors have reported high diagnostic accuracy of brain scanning with radioisotope of sup 32P, sup 42K, sup 206Bi, sup 203Hg, sup 99mTc etc. In 1967, Stern and Wagner first described sup 113mIn chelate, and other authors reported clinical value of sup 11mIn DTPA for brain scanning. Since February, 1970, 140 sup 113mIn brain scan have been carried out and anayzed at Dept. of Radiology and Nuclear medicine of yonsei university. Brain scan is much better to detect optical accuracy in size, shape and location of intracranial lesions without premedication ; therfore. The scan is easier for any type of patients including emergency without complication. On comparison with other radioactive isotopes, In 113m DTPA tracer for brain scan makes not only good resolution for scan image, but also does not collect in the other organ such as choroid plexuses.