분리된 미생물은 pH 4.5내지 pH 8.0에서 100% 안정성을 나타내며 에너지원이 전혀 공급되지 않은 상태에서도 37$^{circ}C$의 용액중에서 48시간 이고 경과시도 80% 이상의 높은 생존율을 나타낸다. 생리식염수에서는 4$0^{circ}C$에서 한 시간 방치하는 경우도 90% 이상의 높은 생존율을 나타낸다는 것을 알수 있었다. 이러한 조건들을 검토해볼 때 생장내 조건에서 상당히 안정하며 경구투여제로 투여하기에 충분히 적당하다고 결론지을 수 있겠다. 특히 포만시에 투여하는 것이 더욱 효과적인 것으로 사료되므로 소화제등과 혼용한 약제로 축발하는 것이 바람직하리라 기대된다.
A microbial strain capable of producing lactic acid was isolated and identified as Streptococcus faecium. During the incubation of the isolated bacterium in a synthetic medium (Petterson broth), the optimal temperature was 36 to 39$^{circ}C$ and the cell concentration at stationary growth phase was 2.1${ imes}$10$^$8/ viable cells/ml. When it was dried in vacuum and diluted with avicel, the Viability of Streptococcus faecium in physiological saline solution was decreased to 80％ after incubation for 48 hr at 37$^{circ}C$, whereas the viability was above 90％ after incubation for 1 hr at 40$^{circ}C$ and the viability in M buffer solution (pH 4.5∼9.0) at 37$^{circ}C$ was above 95％. From these data it was concluded that the isolated microbe must be adoptible for pharmaceutical preparation such as solid dosage form.
