Irradiation at the Yonsei Cancer Center was carried out in 54 patients with laryngeal cancer. Of these 54 patients, 23 were reviewed in respect of tumor regression on the laryngogram after radiation therapy. On the laryngogram, minimal degree of tumor regression were observed in patients of 4 cases in supraglottic cancer, 1 case of glottic cancer and 6 cases of transglottic cancer. And, moderate degree of tumor regression was observed in patients of 2 and 8 cases in the supraglottic regions respectively. The value of the roentgenographic study of the larynx and hypopharynx lies in the determination of the precise anatomical location of the lesion, as well as its size and extent, and the delineation of involvement of adjacent structures. The degree of functional impairment of the involved structures can also be demonstrated. The roentgen findings confirm and supplement the clinical observations. Therefore, the contrast examination of laryngopharynx is invaluable to the radiothe apist and the otolaryngologist for diagnosis, treatment planning and follow-up studies of tumors of the larynx and hypopharynx.