General purpose programs are essential elements for the computerization of structural analysis. This paper is associated with actual formulation of such programs by matrix analysis. The basic theory of matrix analysis for skeletal structures, its implementation and techniques for developing efficient programs are discussed in this paper. Any shape of skeletal structure can be included in a single program for space frames. But in order to economize computing time and computer memory space, it is desirable to develop and operate seperate programs specialized into four categories; truss, planar frame, grid and space frame. As for general purpose programs, simplicity of input format and flexibility of output format should be duly considered. Compaction and solution of system equations are the most important aspects in computer programming of matrix analysis, and worth further study for more efficient computerization.