Cryptococcosis is a cosmopolitan mycotic disease caused by a yeast like fungus, Cryptococcuss neoformans. Resiratory tract, as portal of entry, is the initial focus of infection. Initial pulmonary lesion may heal with or without dissemination of the disease. Authors reviewed 8 cases of confirmed cryptococcosis during Jan. 1973 to June 1981 at Seoul National University Hospital. The results are as follows ; Majority of the cases are below 5 years old. The most common symptoms are fever, abdominal pain and distension, and repiratory symptoms in only 2 cases. The involved organs are liver, lymph node, spleen , meninges, and skin in the order of frequency. Chest P-A roentgenograms show both hilar enlargement with perihilar and basilar , linear and small nodular infiltrations. Miliary nodular lesions and mediastinal lymphadenopathy were also noted.