Endoscopic retrograde cholangiopancreatography (ERCP) is an new diagnostic method for pancreatic and biliary disease which has been made possible by the development of fiberoptic duodenoscopy. It has been thought that ERCP which serve an important in the early detection of pancreatic cancer, but in order to detect minor lesions of the pancreas and improve the diagnostic accuracy of resectable pancreatic cancer, Endoscopic Retrograde Parenchymography of the pancreas (ERPP) was developed recently. The authors analyzed 117 cases of ERCP performed at the Kwangju Christian Hospital between January and December 1980 , and compared them with the final diagnosis. The results were as follows : 1. Out of 117 cases, successful visualization of the duct of concern was achieved in 105 cases. Of these, 25 cases were ERPP. 2. The ratio of males to female was 1.44 : 1, Most patients were in the 4th to 6th decade. 3. The commonest clinical manifestations were upper abdominal pain (77 cases), aundice (23 cases), indigestion, vomiting and abdominal mass, in order of frequency. 4. Out of 46 cases of suspected pancreatic disease, the pancreatic duct was visualized in 36 cases, and 24 cases revealed pathognomonic findings, These were diagnosed as 16 cases of pancreatic cancer, 4 cases of chronic pancreatis, 2 cases of pancreatic pseudocyst and 2 cases of periampullary cancer with pancreas invasion . In pancreatic cancer findings were ; encasement, local dilatation, delayed extretion, poor filling, obstruction of pancreatic duct, accompanying C.B.D. obstruction or stenosis and so called double duct sign. The chronic pancreatitis findings included ; ductal dilatation (with or without) obstruction , tortuosity with dilated saccular lateral branching, stone formation and the parenchymal filling defect. 5. Out of 71 cases of suspected biliary tract disease, the biliary tract was visualized in 57 cases , and in 31 cases abnormalities were suggested ; such as 20 cases of biliary st ne, 1 cases of ascariasis, 1 case of clonorchiasis with cholangitis, 1 case of clonorchiasis with stone , 2 cases of C.B.D. ca. 2 cases of G.B ca, 3 cases of intrahepatic disease, 1 cases of stones in the biliary tree with ampullary ca. 6. Complications of ERCP and ERPP were extremely rare. TRansient abdominal distention, abdominal discomfort and elevated serum amylase were noted, but were not clinically signifianct.