It is necessary to improve new silkworm variety suitable for the artificial diet different from the mulberry leaves in physical and chemical natures. The silkworms fed on artificial diet show low productivity in general. So the effectiveness of selection for cocoon characters was studied when the silkworms were reared on the artificial diet for several generations. The results obtained are as fellows: 1. There is no correlation between the cocoon shell weight and the cocoon shell percentage in female cocoons of both Sa and Y strains but in male cocoons. 2. No correlation exists between the weight of a cocoon and a cocoon shell percentage of male cocoons in Sa strain. 3. There is a specific effect of the artificial diet on selection between Japanese and Chinese strains compared with the mulberry leave rearing. 4. The cocoon quality of first generation in artificial diet rearing was very inferier to that of previous generation in mulberry leave rearing in both Sa and Y strains, but the effect of selection rapidly increased in first and second generation.5. Very high mortality was noted in 4th generation to the degree of hardness for successive generation. 6. From 6th generation to 10th generation, the effectiveness of selection for cocoon characters increased continuously except the cocoon shell percteage.