- Indomethacin 제제(製劑)의 용출(溶出)에 관한 연구(硏究)
- ㆍ 저자명
- 백완숙,김희준,김길수,이해빈,Paik. W.S.,Kim. H.J.,Kim. K.S.,Lee. H.B.
- ㆍ 간행물명
- 藥劑學會誌
- ㆍ 권/호정보
- 1983년|13권 3호|pp.104-109 (6 pages)
- ㆍ 발행정보
- 한국약제학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The effect of diluents on the dissolution rate of indomethacin was studied and the dissolution rate for the marketed products was compared to establish the quality standard for indomethacin preparation. The results are as fellows 1. The effect of test methods was not significant in the case of paddle method but was greatly effected in the case of basket method. 2. The effect of diluents was not significant generally, but in the case of starch dissolution rate was greatly effected. 3. The dissolution rate was remarkably decreased in proprotion to increase of capsule size. 4. The marketed products met the KP dissolution requirement but showed a little difference due to manufacturers.