Paragonimiasis is prevalent if Far East and a kind of endemic Korea diseases. The primary site of human paragonimiasis is the lung, but the ectopic infection of lung fluke has been reproted by many authors. We experienced one case of abdominal paragonimiasis in a 44 year old male with a complaint of left lower originating from the wall of descending colon. (intramural tumor). Postoperative specimen taken from the solid tumorous lesion showed parasitic granuloma, characteristic of Paragonimus Westermani. Here, we report a case of very peculiar ectopic paragonimiasis involved descending colon wall simulating neoplastic tumor, and also review the literatures briefly.