Toxohormone-L 유도 지방 분해 활성은 인삼의 지용성 추출물(LGX)에 의하여 증가되나 인삼의 수용성 추출물(WGX)에 의하여는 다소 (P<0.1) 방해되었다. Adrenaline 유도 지방 분해 활성은 LGX나 WGX에 의한 영향을 받지 않았다. 체내 총지질함량은 정상 생쥐의 복강에 LGX를 주사했을 때 변화가 없었으나 Salcoma 180 cell들을 갖는 생쥐에게 LGX를 주사하면 주사하지 않은 생쥐보다 더욱 낮아졌다.
This work examined the effect of light petroleum ginseng extract (LGX) and water soluble ginseng extract (WGX) on the lipolytic substance (toxohormone-L) in the ascites fluid of mice with Salcoma ISO cells and adrenaline induced lipolysis. In vitro test, the toxohormone-L induced lipolysis was clearly stimulated by LGX but was slightly inhibited(P<0.1) by WGX. While, adrenaline induced lipolysis in fat cells was not affected by LGX or WGX. In vivo test, there were no changes of total body lipid contents in LGX treated mice compared with control mice, but total body lipid contents in Salcoma 180 cells bearing mice.
