Eighty-eight patients who presented with a variety of head and neck symptoms were examined with intravenous or intraarterial digital subtraction angiography(IV or IA DSA), using the DSA equipment developed by Seoul National University Hospital. A grading system was used to evaluate the ability of DSA to answer specific diagnostic questions. Diagnostic information without need of further study was obtained in 71% with IV DSA, in 86% with aortic arch DSA and in 81% with selective arterial DSA, showing a total of 79% of diagnostic accuracy with DSA. It is concluded that IV DSA is useful in the evaluation of the cervical carotid and vertebral arterial disease, and pituitary mass lesion, while IA DSA is useful in the evaluation of most of the intracranial lesions, spinal arteriography and intra-arterial embolization. DSA is both an accurate and safe imaging modality in the study of head and neck diseases.