This paper represent the design of a digital modem which transmits the ECG data from an ambulatory arrhythmia monitor over the telephone lines to a large hospital for the instantaneous interpretations. The digital modem provides on-line communications between the patient and the central computer located near cardiologists. For commercial telephone lines, the transmitting error rates of the digital modem were measured 200 times at a speed of 300 baud. In those measurements, the block errors-results, due to the misinterpretation of start and stop bits, did not occur, The data bit errors which were due to a single bit interpreted incorrectly were 0.78 (bits/10 ) . Since the acceptable data bit error limit is 10 per 106 bits transmitted, the digital modem designed in this paper can be used for the clinical applications without any difficulty.