Veronicastrum sibiricum (L.) Pennell (Scrophulariaceae) is a perennial herb growing in moist land. It has been used as a korean folk medicine in treating common cold, leucorrhea, cystitis and liver damage and as cholagogue. The present study dealt with the elucidation of the chemical components. From the roots of the plant, five iridoids were isolated and identified as minecoside $(mp;142{sim}3^{circ})$, 6-O-veratryl catalpol ester $(mp;216{sim}8^{circ})$, catalpol $(mp;204{sim}6^{circ})$, aucubin $(mp;180{sim}2^{circ})$ and 6-desoxy-8-isoferuloyl harpagide $(mp;139{sim}41^{circ})$. Furthermore, ${eta}-sitosteryl-3-O-D-glucoside$, campesteryl 3-O-D-glucoside, ${eta}-sitosterol$, campesterol, stigmasterol and mannitol were also isolated.