Studies were aimed to analyse computed tomography images and time-density curve reconstructed from the serial CT images in experimentally induced acute renal failure of the rabbits using dynamix CT, and to try to evaluate inthe functional aspect, and finally to promote the better understanding of pathophysiology of ARF. RESULTS : 1. On the sequential CT image, the cortical and the medullary densities of group I were rapidly increased and decreased. 2. In the TDCs of group I, the densities of aorta, cortex and medulla increased sequentially to form peaks and then declined rapidly in order. 3. The cortical curves of group II and III were increased to form high peaks and decreased rapidly. Themedullary curves were low and flat. 4. In group IV, both cortex and medulla showed lower curves than thoses in group I. 5. Between the curves of aorta and cortex, and the curves of cortex and medulla in ARF groups, junction times were delayed or the curves did not intersect apparently. These studies were able to demonstrate meaningful differences I both the dynamic CT mages and the functional curves of the control and two experimental ARF models.