- 제조및 포장조건에 따른 비등정의 안정성 비교
- The Effect of Manufacturing and Packaging Conditions on the Stability of Effervescent Tablets
- ㆍ 저자명
- 차봉진,김근혁,권종원,양중익,민신홍
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 1987년|31권 2호|pp.60-63 (4 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The effect of manufacturing and packaging conditions on the stability of effervescent tablets has been studied. Mixtures of sodium bicarbonate and tartaric acid were compressed at tabletting forces of 3,6, and 9 ton force. Tablets were more than simple physical mixture but the effect of tabletting force has not been found in this force range. "Curing" the tablet by heating it to $90^{circ}C$ was effective on increasing the stability and the silica gel in the aluminium pouch stabilized the system. The equipment measuring the carbon dioxide pressure in this experiment was very useful in evaluation of the effervescent tablets.t tablets.