- 해당화 지하부의 혈청 Cholesterol치 저하효과
- The Serum Cholesterol Level Lowering Effect from the Underground Parts of Rosa rugosa
- ㆍ 저자명
- 양한석,박종철,최재수,정해영
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 1987년|31권 6호|pp.394-398 (5 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The present paper describes the serum cholesterol level lowering effect of the underground parts of Rosa rugosa(Rosaceae) which have been used in a folkloric medicine for treating diabetics. The methanol extract was shown to lower the serum lipid level against the normal and 1% cholesterol and 0.5% cholic acid diet feeding to rats, respectively. When various fractions prepared from the above methanol extract was administered, the ethyl acetate-soluble fractions lowered the serum cholesterol level most remarkably. And when (+)-catechin from the ethyl acetate-soluble fractions was only administered to them, the serum cholesterol level was significantly lowered to 260$pm$9.3mg/dl, the decrease of 17% for the control group. Therefore, it is suggested that (+)-catechin is one of the active principles of this plant.