Ewing`s sarcoma is a highly malignant tumor which occurs most frequently in the diaphysis of the long bones, although any bone may be involved. Ewing`s sarcomas occurring in the rib are rare. Recently, we experienced one case of Ewing`s sarcoma which arose in the right second rib in a young female patient. She was treated with three principal treatment modalities-en bloc excision of chest wall followed by radiation therapy and chemotherapy. Clinical course is described with review of related literatures.