The authors studied anxiety-depression using New Anxiety-Depression Scale(NADS), in the subjects of 3,499male and 1,335 female college freshmen of Yeungnam University. The authors collected the reports of NADS during the periods from January to February, 1986, and applied ANOVA and t-test on anxiety-depression scores in order to compare them between various psychosocial factors, and sexs. The results are as follows : There was significant difference in the mean awerages of total scores between male and female students: male students scored $31.49{pm}6.57$ female students scored $33.37{pm}6.84$ (P<0.001) The anxiety-depression scores relating to the items of sleep disturbance, apprehension, decreased libido and fatigue were relatively higher in both groups. Ninety-nine male students(2.8%) showed seriously high degree anxiety-depression scores of 50 or higher, while forty female students(3.0%) showed the same scores. There was a strong tendency toward higher anxiety-depression scores in the students who were dissatisfied with their home atmosphere, colleges, departments and familiarity of parents, and those who had pessimistic views of self image in the past, present, or fartare in both groups (P<0.001) The students whose maturation locations were below city level, showed higher level of anxiety-depression scores in both groups (P<0.05) NADS and SAS, SDS, and Leeds scale were correlated significantly in 0.64, 0.61, and 0.77 of correlation coefficient.