Osteogenesis imperfecta has been categorized as a heritable disorder of connective tissue affecting both bone and soft tissues and is characterized by fragility of bone, blue sclerae, and deafness, less frequently by dentinogenesis imperfecta and laxity of ligament. The goals of orthopedic management with osteogenesis imperfecta are the treatment of acute fractures and long-term rehabilitation in an effort to maintain ambulation. We report a case of osteogenesis imperfecta with anterior bowing of tibia which was successfully corrected by multiple osteotomies and intramedullary fixation by Sofield method and reviewed literatures.