The authors studied anxiety-depression using New Anxiety-Depression Scale (NADS) in the subjects of 2.564 male and 1,252 female college freshmen of Yeungnam University. The authors collected the reports of NADS during the periods from January to February 1987, and applied NAOVA and t-test on anxiety depression scores in order to compare them between various psychosocial factors and sexes. The results are as follows : There was significant difference in the mean average of total scores between male and female students : male students scored $33.41{pm}8.76$ and female students scored $35.34{pm}9.02$ (P<0.001). The anxiety-depression scores relating to the items of sleep disturbance, apprehension, facial flushing and fatigue were relatively scored higher in both groups. One hundred and thirty nine male students (5.4%) showed seriously higher degree of anxiety-depression scores of 50 or more, while eighty eight female students (7.0%) showed the sane scores. There was a strong tendency toward higher anxiety-depression scores in the students who were dissatisfied with their home atmosphere, colleges, departments, familiarity of parents am those who had pessimistic views of self image in the past, presents and future in both groups (P<0.001).