This experiment was conducted to examine the $PGF{2{alpha}}$-induced changes in concentrations of ovarian and pituitary hormones of Korean native goats. Each goats received two injections of $PGF{2{alpha}}$ (5mg each ; 3 hours apart) on day 10 of the estrous cycle. Jugular venous blood samples were collected at 0, 3, 6, 12, 24, 48 and 72 hours postinjection for quantification of LH, FSH, prolactin, progesterone and estradiol-$17{eta}$. The results were summarized as follows ; The blood serum concentration of progesterone was decreased from pretreatment level of $4.15{pm}1.8ng/ml$ to $2.52{pm}1.2ng/ml$ (about 60%) within 3 hours and to $0.81{pm}0.3ng/ml$ at 12 hours of the $PGF{2{alpha}}$ injection. After 12 hours, the concentrations of progesterone were less than 1.02ng/ml by 72 hours postinjection. The concentrations of estradiol-$17{eta}$ following treatment increased (p < 0.05) over the 72 hours. Initial concentration of LH was $3.0{pm}0.3{mu}IU/ml$. After treatment with $PGF{2{alpha}}$, concentrations of LH increased within 12 hours but declined 12 and 72 hours from $4.1{mu}IU/ml$ to $2.5{mu}IU/ml$. Prior to administration of $PGF{2{alpha}}$, mean concentration of FSH was $3.5{pm}0.5{mu}IU/ml$. Concentrations of FSH declined over time in goats treated with $PGF{2{alpha}}$ on day 10 postestrus. The mean prolactin concentrations in the blood serum after $PGF{2{alpha}}$ treatment were not significantly different from those of the pretreatment. It is concluded that the initial increase in LH is dependent on a decrease in serum progesterone and differences in patterns of secretion of gonadotropins might be caused by differences in progesterone or progesterone-estradiol ratio when luteal regression is induced on day 10 of the estrous cycle.