The improvement of volumetric efficiency of air charging into combustion chamber is a primary requirement to obtain better mean effective pressure of an engine. Since parameters such as the air resistances in intake and exhaust flow passages, valve lift and valve timing influence greatly to the volumetric efficiency, it is very convenient and time saving if we can optimize these parameters by computation before we enter into long time fact finding engine tests. In this study we have developed a semi-empirical engine simulation program for the determinations of intake and exhaust valve timings, valve lifts, intake and exhaust port diameters in order to obtain highest volumetric efficiency. In this computation it requires only the measured variational pressures in intake and exhaust port. Using these variational pressures as an input data for our simulation program, we can calculate volumetric efficiency more accurately and can save computing time drastically. To confirm the validity of our simulation program we have made engine operation test in parallel and taken the experimental data. Comparing the computation result with the experimental data obtained through real engine test it has shown only the difference of 3%.