A multiple box model which is suitable for the prediction of water quality in shallow lakes with active mixing is a water quality model expected to be used widely in estuary reservoir. In this study, a multiple box water quality model for estuary reservoirs (MBQER) was developed arid the applicability of the MBQER was tested by applying data obtained from Asan-estuary reservoir. The results of this study can be summarized as follows. 1. The MBQER, dynamic water quality model, was developed to estimate 10-day water qualities of estuary reservoirs. For the proper analysis and the application of hydraulics needed to build a model, lake hydraulics was simplified by condisering only hydrological inflow and lake mixing currents. The box division in the MBQER is longitudinal one dimension for upper and middle part, and two layers for lower part of the reservoir. 2. The methods of box division for the multiple box model were ekamined and applied to Asan-estuary reservoir. For determining the number of boxes, Pe number and Pk number were used. In case of three boxes, the error by the model simplification would be estimated about 5 % Therefore, in Asan reservoir, the proper number of boxes was three. 3. The MBQER was calibrated and verified using measured data in Asan-estuary reservoir from 1986 to 1988. The Root Mean Squares(RMS) for the differences between measured data and simulated results by the MBQER were 1.10$^{circ}$C C for water temperature, 75.8mg/1 for salinity, 0.082mg/1 for total-phosphorus showing good estimations. 4. Through the simulation of water temperature and salinity by the MBQER, the exchange flow and the mixing coefficients for the estuary lake were determined. As a result of simulation, the horizontal mixing coefficients in Asan-estuary reservoir were in the range of 1.07X 105 to 1.12X 105 cm$^2$/sec and vertical mixing coefficient was 2.90X 10-1 cm$^2$/sec.