In this study, finely divided vanadium pentoxide was prepared by carrying vapor of vanadyl trichloride into the flame of an C3H8-O2-H2 with a specially designed burner. The flame-synthesized oxide particles had a nonporous spherical shape with nearly constant diameter in the range of 200-600$AA$. The surface area of these particles depends on the residence time and the concentration of metal chloride vapor in the burner. The experimental results showed that the growth of particles is controlled by fusion rather than collision. The crystal size of finely divided V2O5 particle was increased after calcination at temperature above 50$0^{circ}C$.